Targeted production of secondary metabolites by coexpression of non-ribosomal peptide synthetase and prenyltransferase genes in Aspergillus

Tentative biosynthetic pathways of some microbial diketopiperazines

(2013) Binbin Gu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Catalytic Mechanism of Stereospecific Formation of cis-Configured Prenylated Pyrroloindoline Diketopiperazines by Indole Prenyltransferases

(2013) Xia Yu et al.   CHEMISTRY & BIOLOGY

CdpC2PT, a reverse prenyltransferase from Neosartorya fischeri with a distinct substrate preference from known C2-prenyltransferases

(2013) K. Mundt et al.   MICROBIOLOGY-SGM

A Branched Biosynthetic Pathway Is Involved in Production of Roquefortine and Related Compounds in Penicillium chrysogenum

(2013) Hazrat Ali et al.   PLoS One

Prenylation at the indole ring leads to a significant increase of cytotoxicity of tryptophan-containing cyclic dipeptides

(2012) Beate Wollinsky et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification of the Verruculogen Prenyltransferase FtmPT3 by a Combination of Chemical, Bioinformatic and Biochemical Approaches

(2012) Kathrin Mundt et al.   CHEMBIOCHEM

2,5-Diketopiperazines: Synthesis, Reactions, Medicinal Chemistry, and Bioactive Natural Products

(2012) Alan D. Borthwick   CHEMICAL REVIEWS

Structure and Catalytic Mechanism of a Cyclic Dipeptide Prenyltransferase with Broad Substrate Promiscuity

(2012) Jan Michael Schuller et al.   JOURNAL OF MOLECULAR BIOLOGY

Regulation of fungal secondary metabolism

(2012) Axel A. Brakhage   NATURE REVIEWS MICROBIOLOGY

Heterologous expression system in Aspergillus oryzae for fungal biosynthetic gene clusters of secondary metabolites

(2011) Kanae Sakai et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A Single Cluster of Coregulated Genes Encodes the Biosynthesis of the Mycotoxins Roquefortine C and Meleagrin in Penicillium chrysogenum

(2011) Carlos García-Estrada et al.   CHEMISTRY & BIOLOGY

NRPSpredictor2—a web server for predicting NRPS adenylation domain specificity

(2011) Marc Röttig et al.   NUCLEIC ACIDS RESEARCH

Anthranilate-Activating Modules from Fungal Nonribosomal Peptide Assembly Lines

(2010) Brian D. Ames et al.   BIOCHEMISTRY

Fungal secondary metabolites – Strategies to activate silent gene clusters

(2010) Axel A. Brakhage et al.   FUNGAL GENETICS AND BIOLOGY

Genome mining and biosynthesis of fumitremorgin-type alkaloids in ascomycetes

(2010) Shu-Ming Li   JOURNAL OF ANTIBIOTICS

Genome-Based Characterization of Two Prenylation Steps in the Assembly of the Stephacidin and Notoamide Anticancer Agents in a Marine-DerivedAspergillussp.

(2010) Yousong Ding et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reconstruction of pyrrolo[2,3-b]indoles carrying an α-configured reverse C3-dimethylallyl moiety by using recombinant enzymes

(2010) Wen-Bing Yin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Preparation of pyrrolo[2,3-b]indoles carrying a β-configured reverse C3-dimethylallyl moiety by using a recombinant prenyltransferase CdpC3PT

(2010) Wen-Bing Yin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Improved tryprostatin B production by heterologous gene expression in Aspergillus nidulans

(2009) Shubha Maiya et al.   FUNGAL GENETICS AND BIOLOGY

Prenylated indole derivatives from fungi: structure diversity, biological activities, biosynthesis and chemoenzymatic synthesis

(2009) Shu-Ming Li   NATURAL PRODUCT REPORTS

Metabolomics ofAspergillus fumigatus

(2008) Jens C. Frisvad et al.   MEDICAL MYCOLOGY