Article
Endocrinology & Metabolism
Alessio Basolo, Takafumi Ando, Douglas C. Chang, Tim Hollstein, Jonathan Krakoff, Paolo Piaggi, Susanne Votruba
Summary: The study found that lower serum albumin concentration was associated with greater daily energy intake and weight gain, suggesting albumin may be a marker of energy intake regulation.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Behavioral Sciences
Rosario B. Jaime-Lara, Alexis T. Franks, Khushbu Agarwal, Nafisa Nawal, Amber B. Courville, Juen Guo, Shanna Yang, Brianna E. Brooks, Abhrarup Roy, Karen Taylor, Valerie L. Darcey, James D. Lecheminant, Stephanie Chung, Ciaran G. Forde, Kevin D. Hall, Paule Joseph
Summary: This study found that a 2-week consumption of ultra-processed food did not have a significant impact on sweet or salty taste sensitivity or preference. However, a positive correlation was observed between salt taste preference and systolic blood pressure, body weight, and BMI following consumption of the ultra-processed diet.
Article
Cell Biology
Christoffer A. Hagemann, Malene S. Jensen, Stephanie Holm, Laerke S. Gasbjerg, Sarah Byberg, Kirsa Skov-Jeppesen, Bolette Hartmann, Jens J. Holst, Flemming Dela, Tina Vilsboll, Mikkel B. Christensen, Birgitte Holst, Filip K. Knop
Summary: This study investigates the effects of exogenous LEAP2 on postprandial glucose metabolism and ad libitum food intake. The results show that LEAP2 infusion lowers postprandial plasma glucose and growth hormone concentrations and decreases food intake.
CELL REPORTS MEDICINE
(2022)
Article
Clinical Neurology
Christopher M. Depner, Edward L. Melanson, Robert H. Eckel, Janine A. Higgins, Bryan C. Bergman, Leigh Perreault, Oliver A. Knauer, Brian R. Birks, Kenneth P. Wright
Summary: Insufficient sleep is believed to promote weight gain. However, increasing weekend sleep duration did not significantly impact energy balance according to this study.
Article
Clinical Neurology
Christopher M. Depner, Edward L. Melanson, Robert H. Eckel, Janine A. Higgins, Bryan C. Bergman, Leigh Perreault, Oliver A. Knauer, Brian R. Birks, Kenneth P. Wright
Summary: The study found that increasing weekend recovery sleep does not improve the positive energy balance and weight gain caused by insufficient sleep.
Article
Nutrition & Dietetics
Mette S. Nielsen, Christian Ritz, Anne Chenchar, Wender L. P. Bredie, Matthew P. Gillum, Anders Sjodin
Summary: The study investigated the impact of bariatric surgery on FGF21 levels and sweet food intake, concluding that there was no significant change in FGF21 levels post-surgery and individual changes in FGF21 did not mediate the effect of surgery on sweet food intake and preference.
Article
Behavioral Sciences
Emily E. Perszyk, Xue S. Davis, Dana M. Small
Summary: The fidelity of olfactory decoding is influenced by hunger/satiety state and food intake, but not by body weight regulation.
Article
Biochemistry & Molecular Biology
Kevin D. Hall, Juen Guo, Amber B. Courville, James Boring, Robert Brychta, Kong Y. Chen, Valerie Darcey, Ciaran G. Forde, Ahmed M. Gharib, Isabelle Gallagher, Rebecca Howard, Paule V. Joseph, Lauren Milley, Ronald Ouwerkerk, Klaudia Raisinger, Irene Rozga, Alex Schick, Michael Stagliano, Stephan Torres, Mary Walter, Peter Walter, Shanna Yang, Stephanie T. Chung
Summary: In an inpatient, randomized controlled crossover trial, participants consumed 550-700 fewer calories per day when following a plant-based, low-fat diet with a high glycemic load compared with an animal-based, low-carbohydrate diet with a low glycemic load; weight loss was comparable between the two diets and there were no significant differences in hunger or enjoyment of the meals.
Article
Behavioral Sciences
Angelica M. Monge, Danielle Ferriday, Simon Heckenmueller, Jeffrey M. Brunstrom, Peter J. Rogers
Summary: This study examined the impact of low-calorie sweeteners on compensatory responses. The results were inconsistent with the predicted effect, as there was no significant difference in snack intake between low-calorie sweetener and sugar soft drink consumers. Additionally, the sweetness of the beverage had an effect on snack intake, but there was minimal compensation for the energy content difference between low-calorie sweetener and sugar cola.
Article
Nutrition & Dietetics
Eric D. B. Goulet, Pascale Claveau, Ivan L. Simoneau, Thomas A. Deshayes, Antoine Jolicoeur-Desroches, Fedi Aloui, Martin D. Hoffman
Summary: Ad libitum water intake during consecutive exercise sessions can maintain similar fluid balance and physiological functions, without significant differences in heart rate, perceived thirst, heat stress, and exertion.
Article
Nutrition & Dietetics
Pernilla Lif Holgerson, Pamela Hasslof, Anders Esberg, Simon Haworth, Magnus Domellof, Christina E. West, Ingegerd Johansson
Summary: This study explores the impact of maternal innate driving forces on sweet taste preference and intake, and whether their children differ in their intake of sweets or traits related to sweet intake. The study identifies two genetic variations associated with preference for sweet taste and intake, which could be potential candidates for a genetic score for sweet intake.
Article
Cell Biology
Sharmili Edwin Thanarajah, Alexandra G. DiFeliceantonio, Kerstin Albus, Bojana Kuzmanovic, Lionel Rigoux, Sandra Iglesias, Ruth Hanssen, Marc Schlamann, Oliver A. Comely, Jens C. Bruening, Marc Tittgemeyer, Dana M. Small
Summary: Western diets rich in fat and sugar can lead to excessive calorie intake and weight gain. However, the exact mechanisms behind these effects are not yet fully understood. To address this, a controlled study was conducted, exposing normal-weight participants to either a high-fat/high-sugar or a low-fat/low-sugar snack for 8 weeks in addition to their regular diet. The high-fat/high-sugar intervention resulted in a decrease in preference for low-fat food, increased brain response to food, and enhanced associative learning, independent of food cues or reward. These neurobehavioral adaptations, unrelated to changes in body weight or metabolic parameters, suggest a direct effect of high-fat, high-sugar foods on the risk of overeating and weight gain.
Article
Nutrition & Dietetics
Fabienne Teysseire, Emilie Flad, Valentine Bordier, Aleksandra Budzinska, Nathalie Weltens, Jens F. Rehfeld, Christoph Beglinger, Lukas Van Oudenhove, Bettina K. Wolnerhanssen, Anne Christin Meyer-Gerspach
Summary: Oral erythritol reduces energy intake in subsequent ad libitum test meal and induces the release of cholecystokinin (CCK) before the meal. This makes erythritol a useful sugar alternative.
Article
Nutrition & Dietetics
Tetsuro E. Okada, Tony Quan, Marc R. Bomhof
Summary: This study investigated the effects of ketone ester on appetite-related hormones and appetite perception after exercise, finding that although ketone ester altered homeostatic regulators of appetite, it did not acutely affect energy intake during the post-exercise period in healthy adults.
FRONTIERS IN NUTRITION
(2021)
Article
Substance Abuse
Allison N. Baker, Alyssa J. Bakke, Steven A. Branstetter, John E. Hayes
Summary: The study found that flavored e-liquids have a significant impact on liking ratings of electronic cigarettes, but do not affect nicotine intake. Participants showed individual differences in liking electronic cigarettes, with flavor and sensory ratings closely associated with liking.
NICOTINE & TOBACCO RESEARCH
(2021)
Article
Nutrition & Dietetics
John D. Sorkin, Mark Manary, Paul A. M. Smeets, Amanda J. MacFarlane, Arne Astrup, Ronald L. Prigeon, Beth B. Hogans, Jack Odle, Teresa A. Davis, Katherine L. Tucker, Christopher P. Duggan, Deirdre K. Tobias
Summary: This article discusses the appropriate use of P values in accordance with the scientific method, as well as increasing transparency and reproducibility in nutrition research. The proper use of P values and research transparency are crucial for building trust and ensuring the replicability of study results.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Correction
Neurosciences
L. Charbonnier, F. van Meer, A. M. Johnstone, D. Crabtree, W. Buosi, Y. Manios, O. Androutsos, A. Giannopoulou, M. A. Viergever, P. A. M. Smeets
Article
Multidisciplinary Sciences
E. M. Postma, P. A. M. Smeets, W. M. Boek, S. Boesveldt
Summary: This study explored the impact of etiology and duration of olfactory loss (OL) on gray matter volume (GMV) in brain regions, finding significant differences in GMV between congenital anosmia and acquired OL patients, particularly in areas like the orbitofrontal cortex (OFC). The volume of the left OFC was significantly associated with olfactory function, indicating that changes in GMV in acquired OL patients mainly occur in the OFC and are dependent on olfactory function.
SCIENTIFIC REPORTS
(2021)
Letter
Nutrition & Dietetics
John D. Sorkin, Mark Manary, Paul A. M. Smeets, Amanda J. MacFarlane, Arne Astrup, Ronald L. Prigeon, Beth B. Hogans, Jack Odle, Teresa A. Davis, Katherine L. Tucker, Christopher P. Duggan, Deirdre K. Tobias
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Behavioral Sciences
L. N. van der Laan, E. K. Papies, A. Ly, P. A. M. Smeets
Summary: This study investigated the neural mechanisms of health goal priming using fMRI and a virtual reality food choice task. The results showed that virtual reality has potential for a more realistic assessment of food choice processes. However, the study did not find evidence of health goal priming triggering neural self-control mechanisms.
Article
Neurosciences
Esther Walton, Fabio Bernardoni, Victoria-Luise Batury, Klaas Bahnsen, Sara Lariviere, Giovanni Abbate-Daga, Susana Andres-Perpina, Lasse Bang, Amanda Bischoff-Grethe, Samantha J. Brooks, Iain C. Campbell, Giammarco Cascino, Josefina Castro-Fornieles, Enrico Collantoni, Federico D'Agata, Brigitte Dahmen, Unna N. Danner, Angela Favaro, Jamie D. Feusner, Guido K. W. Frank, Hans-Christoph Friederich, John L. Graner, Beate Herpertz-Dahlmann, Andreas Hess, Stefanie Horndasch, Allan S. Kaplan, Lisa-Katrin Kaufmann, Walter H. Kaye, Sahib S. Khalsa, Kevin S. LaBar, Luca Lavagnino, Luisa Lazaro, Renzo Manara, Amy E. Miles, Gabriella F. Milos, Alessio Maria Monteleone, Palmiero Monteleone, Benson Mwangi, Owen O'Daly, Jose Pariente, Julie Roesch, Ulrike H. Schmidt, Jochen Seitz, Megan E. Shott, Joe J. Simon, Paul A. M. Smeets, Christian K. Tamnes, Elena Tenconi, Sophia Thomopoulos, Annemarie A. van Elburg, Aristotle N. Voineskos, Georg G. von Polier, Christina E. Wierenga, Nancy L. Zucker, Neda Jahanshad, Joseph A. King, Paul M. Thompson, Laura A. Berner, Stefan Ehrlich
Summary: Our study found substantial reductions in cortical thickness, subcortical volumes, and cortical surface area in patients with AN. These deficits were associated with lower body mass index in the AN sample and were less pronounced in partially weight-restored patients. These findings underscore the importance of considering weight loss and renutrition in research on AN.
BIOLOGICAL PSYCHIATRY
(2022)
Article
Chemistry, Applied
Ruoxuan Deng, Aurimas Seimys, Monica Mars, Anja E. M. Janssen, Paul A. M. Smeets
Summary: Gastric digestion is essential for protein breakdown and magnetic resonance techniques show potential in studying this process. A novel MRI-compatible semi-dynamic gastric simulator was developed to monitor digestion under dynamic circumstances, showing high potential for future in vivo studies in monitoring nutrient hydrolysis and pH changes.
FOOD HYDROCOLLOIDS
(2022)
Review
Neurosciences
M. T. de Klerk, P. A. M. Smeets, S. E. la Fleur
Summary: Individuals with obesity exhibit poorer food-specific inhibitory control, especially when hungry, and less activation of inhibitory brain areas. Greater activation of inhibitory brain areas is predictive of weight loss success. Interventions targeting inhibitory control in obese individuals have diverse effects, including food-specific inhibitory control training, neuromodulation paradigms, and neurofeedback.
NUTRITIONAL NEUROSCIENCE
(2023)
Article
Chemistry, Applied
Morwarid Mayar, Julie L. Miltenburg, Kasper Hettinga, Paul A. M. Smeets, John P. M. van Duynhoven, Camilla Terenzi
Summary: In this study, we monitored in vitro gastric milk protein digestion using H-1 nuclear magnetic resonance (NMR) magnetization transfer (MT) and found that heated milk has a slower breakdown than unheated milk. This opens the way for future quantification of protein digestion in vivo by MRI.
Article
Neurosciences
Stephanie Kullmann, Ralf Veit, Daniel R. Crabtree, William Buosi, Odysseas Androutsos, Alexandra M. Johnstone, Yannis Manios, Hubert Preissl, Paul A. M. Smeets
Summary: This study investigated the effect of hunger state on the hypothalamus network using functional magnetic resonance imaging, and found that the hypothalamus showed higher functional connectivity with other brain regions in the sated state. Differences in hypothalamus to dorsolateral prefrontal cortex connectivity between individuals with obesity and normal weight were also observed in the fasted state.
HUMAN BRAIN MAPPING
(2023)
Article
Chemistry, Applied
Ruoxuan Deng, Monica Mars, Anja E. M. Janssen, Paul A. M. Smeets
Summary: The structure of food affects its digestion rate, and MRI parameters have been found to serve as markers of protein digestion. In a randomized crossover trial, it was found that high protein and high hardness of food slow down gastric emptying. Additionally, measurements of T1 and T2 provide extra information on the dilution and digestion of solid foods in the stomach.
FOOD HYDROCOLLOIDS
(2023)
Article
Gastroenterology & Hepatology
Elise J. M. van Eijnatten, Guido Camps, Mathilde Guerville, Vincenzo Fogliano, Kasper Hettinga, Paul A. M. Smeets
Summary: This study aimed to compare gastric emptying rate and protein coagulation after milk consumption between individuals reporting gastrointestinal symptoms and those without symptoms. The results showed no difference in gastric emptying rate between the two groups. The group reporting gastrointestinal symptoms started experiencing symptoms at 30 minutes and had the highest pain rating at 90 minutes. Image texture analysis showed a higher percentage of coagulum and lower percentage of liquid in the gastrointestinal symptom group.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Neuroimaging
Elbrich M. Postma, Julia M. H. Noothout, Wilbert M. Boek, Akshita Joshi, Theresa Herrmann, Thomas Hummel, Paul A. M. Smeets, Ivana Isgum, Sanne Boesveldt
Summary: The automatic segmentation method developed in this study accurately segmented the olfactory bulbs (OBs) and showed strong correlation with manual segmentation. OB volume was significantly related to age, duration and etiology of olfactory loss, and olfactory ability. The method can be applied in clinical and research populations, providing insight into the role of OB volume in diagnosis, prognosis, and treatment of olfactory loss.
NEUROIMAGE-CLINICAL
(2023)
Article
Chemistry, Applied
Dan Liu, Anja E. M. Janssen, Paul A. M. Smeets, Markus Stieger
Summary: The study found that the microstructure, mechanical properties, and macrostructure breakdown of protein gels have an impact on in vitro protein gastric digestion. The microstructure of the gels significantly affects the digestion rate of proteins, and the effect of Young's modulus on protein digestion depends strongly on the microstructure.
FOOD HYDROCOLLOIDS
(2024)
Proceedings Paper
Engineering, Biomedical
Julia M. H. Noothout, Elbrich M. Postma, Sanne Boesveldt, Bob D. de Vos, Paul A. M. Smeets, Ivana Isgum
Summary: A decrease in olfactory bulb volume may be related to neurodegenerative diseases, and the asymmetry in olfactory bulb volumes observed in COVID-19 patients suggests a potential role in disease progression. An automatic segmentation method shows promising results in assessing olfactory bulb volumes.
MEDICAL IMAGING 2021: IMAGE PROCESSING
(2021)