Both IRF3 and especially IRF7 play a key role to orchestrate an effective cerebral inflammatory response in a mouse model of herpes simplex virus encephalitis

Valacyclovir combined with artesunate or rapamycin improves the outcome of herpes simplex virus encephalitis in mice compared to antiviral therapy alone

(2015) Coraline Canivet et al.   ANTIVIRAL RESEARCH

Functional IRF3 deficiency in a patient with herpes simplex encephalitis

(2015) Line Lykke Andersen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Innate immune response during herpes simplex virus encephalitis and development of immunomodulatory strategies

(2015) Jocelyne Piret et al.   REVIEWS IN MEDICAL VIROLOGY

HSV-1 Targets Lymphatic Vessels in the Eye and Draining Lymph Node of Mice Leading to Edema in the Absence of a Functional Type I Interferon Response

(2013) Katie M. Bryant-Hudson et al.   AMERICAN JOURNAL OF PATHOLOGY

The combination of valacyclovir with an anti-TNF alpha antibody increases survival rate compared to antiviral therapy alone in a murine model of herpes simplex virus encephalitis

(2013) Nicolas Boivin et al.   ANTIVIRAL RESEARCH

TLR3 immunity to infection in mice and humans

(2013) Shen-Ying Zhang et al.   CURRENT OPINION IN IMMUNOLOGY

Recent issues in herpes simplex encephalitis

(2013) Peter G. E. Kennedy et al.   JOURNAL OF NEUROVIROLOGY

Both TRIF and IPS-1 Adaptor Proteins Contribute to the Cerebral Innate Immune Response against Herpes Simplex Virus 1 Infection

(2013) R. Menasria et al.   JOURNAL OF VIROLOGY

Synergistic control of herpes simplex virus pathogenesis by IRF-3, and IRF-7 revealed through non-invasive bioluminescence imaging

(2013) Aisling A. Murphy et al.   VIROLOGY

Antiviral Type I and Type III Interferon Responses in the Central Nervous System

(2013) Frédéric Sorgeloos et al.   Viruses-Basel

Interferon-α (IFNα) neurotoxicity

(2012) Cari Fritz-French et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Activation of host pattern recognition receptors by viruses

(2010) Kiva Brennan et al.   CURRENT OPINION IN MICROBIOLOGY

Interferon Regulatory Factor 3-Dependent Pathways Are Critical for Control of Herpes Simplex Virus Type 1 Central Nervous System Infection

(2010) V. D. Menachery et al.   JOURNAL OF VIROLOGY

Herpes simplex type I (HSV-1) infection of the nervous system: Is an immune response a good thing?

(2009) Christopher D. Conrady et al.   JOURNAL OF NEUROIMMUNOLOGY

Interferon-  Causes Neuronal Dysfunction in Encephalitis

(2009) A. R. Sas et al.   JOURNAL OF NEUROSCIENCE

Control of Herpes Simplex Virus Replication Is Mediated through an Interferon Regulatory Factor 3-Dependent Pathway

(2009) V. D. Menachery et al.   JOURNAL OF VIROLOGY

The Immune Response to Herpes Simplex Virus Type 1 Infection in Susceptible Mice Is a Major Cause of Central Nervous System Pathology Resulting in Fatal Encephalitis

(2008) P. Lundberg et al.   JOURNAL OF VIROLOGY

Characterization of the interferon regulatory factor 3-mediated antiviral response in a cell line deficient for IFN production

(2008) Tracy Chew et al.   MOLECULAR IMMUNOLOGY