Article
Clinical Neurology
Cara E. Geoghegan, Shruthi Mohan, Elliot D. K. Cha, Conor P. Lynch, Caroline N. Jadczak, Kern Singh
Summary: This study found that meeting patient expectations or achieving a minimum clinically important difference (MCID) is significantly associated with patient satisfaction, with MCID achievement potentially being a more consistent and suitable predictor of satisfaction compared to meeting patient expectations.
WORLD NEUROSURGERY
(2021)
Article
Clinical Neurology
James W. Nie, Timothy J. Hartman, Omolabake O. Oyetayo, Keith R. MacGregor, Eileen Zheng, Vincent P. Federico, Dustin H. Massel, Arash J. Sayari, Kern Singh
Summary: A study was conducted to identify perioperative predictors of minimum clinically important difference (MCID) for patients undergoing lateral lumbar interbody fusion (LLIF). Preoperative patient-reported outcome measures were found to be the most consistent predictors for achieving MCID.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
James W. Nie, Timothy J. Hartman, Eileen Zheng, Omolabake O. Oyetayo, Keith R. MacGregor, Vincent P. Federico, Dustin H. Massel, Arash J. Sayari, Kern Singh
Summary: The objective of this study was to establish the minimum clinically important difference (MCID) in anterior lumbar interbody fusion (ALIF) for patient-reported outcome measures of physical function and pain. The results showed that MCID values greatly relied on the calculation method, and the minimum detectable change method was determined as the most appropriate calculation method. The MCID values for ALIF patients were found to be 7.3 for PROMIS-PF, 8.2 for SF-12 PCS, 7.8 for VR-12 PCS, 3.2 for VAS back, and 2.2 for VAS leg.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Conor P. Lynch, Elliot D. K. Cha, Madhav R. Patel, Kevin C. Jacob, Shruthi Mohan, Cara E. Geoghegan, Caroline N. Jadczak, Kern Singh
Summary: This study found that diabetes mellitus (DM) has an impact on outcomes following anterior cervical discectomy and fusion (ACDF), but regardless of DM status, patients may realize similar benefits of ACDF surgery.
WORLD NEUROSURGERY
(2021)
Article
Critical Care Medicine
Jude Moutchia, Robyn L. McClelland, Nadine Al-Naamani, Dina H. Appleby, Kristina Blank, Dan Grinnan, John H. Holmes, Stephen C. Mathai, Jasleen Minhas, Corey E. Ventetuolo, Roham T. Zamanian, Steven M. Kawut
Summary: The 6-minute-walk distance (6MWD) is a significant metric in pulmonary arterial hypertension (PAH), but there is no consensus on the clinically significant minimal change in 6MWD. This study aimed to determine the minimal clinically important difference in 6MWD and found it to be approximately 33 meters for adults with PAH.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Clinical Neurology
James W. Nie, Timothy J. Hartman, Keith R. MacGregor, Omolabake O. Oyetayo, Eileen Zheng, Kern Singh
Summary: This study calculated the minimum clinically important difference (MCID) values using anchor- and distribution-based methods to establish MCID for physical function and pain patient-reported outcome measures (PROMs) in patients undergoing minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) surgery, with the Oswestry Disability Index (ODI) as the anchor.
Article
Clinical Neurology
James W. Nie, Timothy J. Hartman, Keith R. MacGregor, Omolabake O. Oyetayo, Eileen Zheng, Kern Singh
Summary: This study aims to establish the minimum clinically important difference (MCID) for patient-reported outcome measures (PROMs) of physical function and pain for lateral lumbar interbody fusion (LLIF). The MCID thresholds varied widely depending on the calculation method, with the closest to (0,1) ROC approach being the most clinically appropriate.
ACTA NEUROCHIRURGICA
(2023)
Article
Clinical Neurology
James W. Nie, Vincent P. Federico, Timothy J. Hartman, Eileen Zheng, Omolabake O. Oyetayo, Keith R. MacGregor, Dustin H. Massel, Arash J. Sayari, Kern Singh
Summary: The objective of this study was to examine factors associated with delayed time to achieve minimum clinically important difference (MCID) in patients undergoing lumbar decompression (LD) for the Patient-Reported Outcomes (PROs) of Oswestry Disability Index (ODI), Visual Analog Scale (VAS) back, and VAS leg pain. The results revealed several factors associated with early and late achievement of MCID.
ACTA NEUROCHIRURGICA
(2023)
Article
Clinical Neurology
Adam Nessim, Woojin Cho, Xiuyi Alexander Yang, Ariella Applebaum, Richard Sekerak, Sam Brill, Soo Yeon Kim
Summary: The study aimed to determine the incidence and risk factors associated with the development of sacroiliac joint dysfunction following lumbosacral fusion surgery. Findings showed a significantly lower pelvic tilt and L5 incidence in patients with SIJ dysfunction compared to controls, possibly due to weakened hamstring muscles.
Article
Clinical Neurology
Adam Nessim, Woojin Cho, Xiuyi Alexander Yang, Ariella Applebaum, Richard Sekerak, Sam Brill, Soo Yeon Kim
Summary: This study retrospectively reviewed 2069 patients who underwent lumbosacral fusion surgery and found that the incidence of SIJ dysfunction was 3.9%. Patients with SIJ dysfunction had significantly lower PT and L5 incidence compared to controls. This suggests that hamstring muscle strengthening exercise may help decrease the incidence of SIJ dysfunction in these patients.
Article
Clinical Neurology
Vincent P. Federico, James W. Nie, Timothy J. Hartman, Eileen Zheng, Omolabake O. Oyetayo, Keith R. MacGregor, Dustin H. Massel, Arash J. Sayari, Kern Singh
Summary: This study compared anterior cervical discectomy and fusion (ACDF) with cervical disc replacement (CDR) for time to minimum clinically important difference (MCID) achievement and predictors of delayed MCID achievement. The majority of patients achieved MCID in physical function, disability, and back pain outcomes within 2 years, with CDR patients achieving MCID faster in physical function. Early predictors of MCID achievement were CDR procedure, Asian ethnicity, and elevated preoperative pain outcomes, while workers' compensation was a late predictor.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Conor P. Lynch, Elliot D. K. Cha, Nathaniel W. Jenkins, James M. Parrish, Shruthi Mohan, Caroline N. Jadczak, Cara E. Geoghegan, Kern Singh
Summary: This retrospective cohort study aimed to investigate the MCID for PHQ-9 among patients undergoing MIS TLIF. The study found MCID achievement rates at 2 years for PHQ-9, SF-12 MCS, and VR-12 MCS to be 89.2%, 85.6%, and 84.9%, respectively.
Article
Psychiatry
Pal Czobor, Barbara Sebe, Karoly Acsai, Agota Barabassy, Istvan Laszlovszky, Gyoergy Nemeth, Toshi A. Furukawa, Stefan Leucht
Summary: This study aimed to find the minimum clinically important difference (MCID) in patients with predominantly negative symptoms of schizophrenia at its earliest occurrence. The results varied depending on the methods used, indicating the uncertainty in defining MCID and the different criteria for measuring improvement in patients.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Orthopedics
Sze-Ee Soh, Ian A. Harris, Kara Cashman, Emma Heath, Michelle Lorimer, Stephen E. Graves, Ilana N. Ackerman
Summary: This study aimed to estimate the minimal clinically important changes (MCICs) for the HOOS-12 and KOOS-12 assessments among patients undergoing joint replacement for osteoarthritis. Multiple methods were used to calculate MCICs, and the estimates obtained from predictive modeling were found to be the most clinically applicable.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2022)
Review
Health Care Sciences & Services
Jennifer A. Watt, Areti Angeliki Veroniki, Andrea C. Tricco, Sharon E. Straus
Summary: The study explored a distribution-based method to approximate known minimum clinically important differences (MCIDs), which could aid clinical understanding of intervention effects, with baseline-derived MCIDs performing better.
BMC MEDICAL RESEARCH METHODOLOGY
(2021)