Multidisciplinary management of childhood brain tumors: a review of outcomes, recent advances, and challenges

Phase II trial of tipifarnib and radiation in children with newly diagnosed diffuse intrinsic pontine gliomas

(2011) D. A. Haas-Kogan et al.   NEURO-ONCOLOGY

A phase II study of gefitinib and irradiation in children with newly diagnosed brainstem gliomas: A report from the Pediatric Brain Tumor Consortium

(2011) I. F. Pollack et al.   NEURO-ONCOLOGY

Temozolomide in the treatment of children with newly diagnosed diffuse intrinsic pontine gliomas: a report from the Children's Oncology Group

(2011) K. J. Cohen et al.   NEURO-ONCOLOGY

Temozolomide in the treatment of high-grade gliomas in children: a report from the Children's Oncology Group

(2011) K. J. Cohen et al.   NEURO-ONCOLOGY

Primary Neurosurgery for Pediatric Low-Grade Gliomas: A Prospective Multi-Institutional Study From the Children's Oncology Group

(2011) Jeffrey H. Wisoff et al.   NEUROSURGERY

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children’s Oncology Group

(2010) Ian F. Pollack et al.   CHILDS NERVOUS SYSTEM

HDAC5 and HDAC9 in Medulloblastoma: Novel Markers for Risk Stratification and Role in Tumor Cell Growth

(2010) T. Milde et al.   CLINICAL CANCER RESEARCH

A phase I and biology study of gefitinib and radiation in children with newly diagnosed brain stem gliomas or supratentorial malignant gliomas

(2010) J. Russell Geyer et al.   EUROPEAN JOURNAL OF CANCER

Whole-Genome Profiling of Pediatric Diffuse Intrinsic Pontine Gliomas Highlights Platelet-Derived Growth Factor Receptor α and Poly (ADP-ribose) Polymerase As Potential Therapeutic Targets

(2010) Maryam Zarghooni et al.   JOURNAL OF CLINICAL ONCOLOGY

Lack of Efficacy of Bevacizumab Plus Irinotecan in Children With Recurrent Malignant Glioma and Diffuse Brainstem Glioma: A Pediatric Brain Tumor Consortium Study

(2010) Sridharan Gururangan et al.   JOURNAL OF CLINICAL ONCOLOGY

Integrated Molecular Genetic Profiling of Pediatric High-Grade Gliomas Reveals Key Differences With the Adult Disease

(2010) Barbara S. Paugh et al.   JOURNAL OF CLINICAL ONCOLOGY

Universal Poor Survival in Children With Medulloblastoma Harboring SomaticTP53Mutations

(2010) Uri Tabori et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase I Trial of Lenalidomide in Pediatric Patients With Recurrent, Refractory, or Progressive Primary CNS Tumors: Pediatric Brain Tumor Consortium Study PBTC-018

(2010) Katherine E. Warren et al.   JOURNAL OF CLINICAL ONCOLOGY

A lower-dose, lower-toxicity cisplatin–etoposide regimen for childhood progressive low-grade glioma

(2010) Maura Massimino et al.   JOURNAL OF NEURO-ONCOLOGY

Phase II TPDCV protocol for pediatric low-grade hypothalamic/chiasmatic gliomas: 15-year update

(2010) Kavita K. Mishra et al.   JOURNAL OF NEURO-ONCOLOGY

Cannula placement for effective convection-enhanced delivery in the nonhuman primate thalamus and brainstem: implications for clinical delivery of therapeutics

(2010) Dali Yin et al.   JOURNAL OF NEUROSURGERY

Postoperative cerebellar mutism syndrome following treatment of medulloblastoma: neuroradiographic features and origin

(2010) Elizabeth M. Wells et al.   Journal of Neurosurgery-Pediatrics

Atypical Teratoid or Rhabdoid Tumors: Improved Outcome With High-dose Chemotherapy

(2010) Tal Finkelstein-Shechter et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Cross-species genomics matches driver mutations and cell compartments to model ependymoma

(2010) Robert A. Johnson et al.   NATURE

Everolimus for Subependymal Giant-Cell Astrocytomas in Tuberous Sclerosis

(2010) Darcy A. Krueger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Initial testing (stage 1) of AZD6244 (ARRY-142886) by the pediatric preclinical testing program

(2010) E. Anders Kolb et al.   PEDIATRIC BLOOD & CANCER

Spectrum of SMARCB1/INI1 mutations in familial and sporadic rhabdoid tumors

(2010) Katherine W. Eaton et al.   PEDIATRIC BLOOD & CANCER

The Genetic Landscape of the Childhood Cancer Medulloblastoma

(2010) D. W. Parsons et al.   SCIENCE

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas

(2009) Christian Hartmann et al.   ACTA NEUROPATHOLOGICA

Association of molecular alterations, including BRAF, with biology and outcome in pilocytic astrocytomas

(2009) Craig Horbinski et al.   ACTA NEUROPATHOLOGICA

Frequent Amplification of a chr19q13.41 MicroRNA Polycistron in Aggressive Primitive Neuroectodermal Brain Tumors

(2009) Meihua Li et al.   CANCER CELL

Medulloblastoma Variants: Age-Dependent Occurrence and Relation to Gorlin Syndrome--A New Clinical Perspective

(2009) M. L. Garre et al.   CLINICAL CANCER RESEARCH

Neurologic Sequelae of Brain Tumors in Children

(2009) Nicole J. Ullrich   JOURNAL OF CHILD NEUROLOGY

Prognostic factors in pediatric high-grade astrocytoma: the importance of accurate pathologic diagnosis

(2009) Russell K. Hales et al.   JOURNAL OF NEURO-ONCOLOGY

Role of diffusion tensor imaging in resection of thalamic juvenile pilocytic astrocytoma

(2009) Yaron A. Moshel et al.   Journal of Neurosurgery-Pediatrics

Conformal radiotherapy after surgery for paediatric ependymoma: a prospective study

(2009) Thomas E Merchant et al.   LANCET ONCOLOGY

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

(2009) Paul A Northcott et al.   NATURE GENETICS

Treatment of Medulloblastoma with Hedgehog Pathway Inhibitor GDC-0449

(2009) Charles M. Rudin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Large cell/anaplastic medulloblastoma: Outcome according to myc status, histopathological, and clinical risk factors

(2009) Katja von Hoff et al.   PEDIATRIC BLOOD & CANCER

Rapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors

(2009) Catherine Lam et al.   PEDIATRIC BLOOD & CANCER

PET imaging in pediatric neuroradiology: current and future applications

(2009) Sunhee Kim et al.   PEDIATRIC RADIOLOGY

Magnetic resonance spectroscopy in pediatric neuroradiology: clinical and research applications

(2009) Ashok Panigrahy et al.   PEDIATRIC RADIOLOGY

Tandem Duplication Producing a Novel OncogenicBRAFFusion Gene Defines the Majority of Pilocytic Astrocytomas

(2008) David T.W. Jones et al.   CANCER RESEARCH

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

(2008) Stefan Pfister et al.   JOURNAL OF CLINICAL INVESTIGATION

Intensive Multimodality Treatment for Children With Newly Diagnosed CNS Atypical Teratoid Rhabdoid Tumor

(2008) Susan N. Chi et al.   JOURNAL OF CLINICAL ONCOLOGY

Expression of glioma-associated antigens in pediatric brain stem and non-brain stem gliomas

(2008) Hideho Okada et al.   JOURNAL OF NEURO-ONCOLOGY

A phase I trial of temozolomide and lomustine in newly diagnosed high-grade gliomas of childhood

(2008) Regina I. Jakacki et al.   NEURO-ONCOLOGY

Motexafin gadolinium and involved field radiation therapy for intrinsic pontine glioma of childhood: A Children's Oncology Group phase I study

(2008) Kristin A. Bradley et al.   NEURO-ONCOLOGY

Multifactorial analysis of predictors of outcome in pediatric intracranial ependymoma

(2008) Lee Ridley et al.   NEURO-ONCOLOGY

Outcome of children less than three years old at diagnosis with non-metastatic medulloblastoma treated with chemotherapy on the “Head Start” I and II protocols

(2008) Girish Dhall et al.   PEDIATRIC BLOOD & CANCER

Phase I study of SU5416, a small molecule inhibitor of the vascular endothelial growth factor receptor (VEGFR) in refractory pediatric central nervous system tumors

(2008) Mark W. Kieran et al.   PEDIATRIC BLOOD & CANCER

Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features

(2008) Marcel Kool et al.   PLoS One

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE