Neuroprotective and neurorestorative effects of thymosin β4 treatment initiated 6 hours after traumatic brain injury in rats

Erythropoietin promotes neurovascular remodeling and long-term functional recovery in rats following traumatic brain injury

(2011) Ruizhuo Ning et al.   BRAIN RESEARCH

Dose-dependent neurorestorative effects of delayed treatment of traumatic brain injury with recombinant human erythropoietin in rats

(2011) Yuling Meng et al.   JOURNAL OF NEUROSURGERY

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

(2011) Guo-li Ming et al.   NEURON

Maturation time of new granule cells in the dentate gyrus of adult macaque monkeys exceeds six months

(2011) S. J. Kohler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A randomized, placebo-controlled, single and multiple dose study of intravenous thymosin β4 in healthy volunteers

(2010) Dennis Ruff et al.   Annals of the New York Academy of Sciences

Thymosin β4: a candidate for treatment of stroke?

(2010) Daniel C. Morris et al.   Annals of the New York Academy of Sciences

Thymosin β4: structure, function, and biological properties supporting current and future clinical applications

(2010) David Crockford et al.   Annals of the New York Academy of Sciences

Animal modelling of traumatic brain injury in preclinical drug development: where do we go from here?

(2010) Niklas Marklund et al.   BRITISH JOURNAL OF PHARMACOLOGY

Biological activities of thymosin β4 defined by active sites in short peptide sequences

(2010) Gabriel Sosne et al.   FASEB JOURNAL

Regenerative protein thymosin β-4 is a novel regulator of purinergic signaling

(2010) Kevin W. Freeman et al.   FASEB JOURNAL

Treatment of traumatic brain injury with thymosin β4 in rats

(2010) Ye Xiong et al.   JOURNAL OF NEUROSURGERY

Effects of posttraumatic carbamylated erythropoietin therapy on reducing lesion volume and hippocampal cell loss, enhancing angiogenesis and neurogenesis, and improving functional outcome in rats following traumatic brain injury

(2010) Ye Xiong et al.   JOURNAL OF NEUROSURGERY

Therapeutic Window Analysis of the Neuroprotective Effects of Cyclosporine A after Traumatic Brain Injury

(2010) Patrick G. Sullivan et al.   JOURNAL OF NEUROTRAUMA

Thymosin β4 improves functional neurological outcome in a rat model of embolic stroke

(2010) D.C. Morris et al.   NEUROSCIENCE

Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies

(2010) David J. Loane et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Thymosin β4 induces epicardium-derived neovascularization in the adult heart: Figure 1

(2009) Paul R. Riley et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Delayed transplantation of human marrow stromal cell-seeded scaffolds increases transcallosal neural fiber length, angiogenesis, and hippocampal neuronal survival and improves functional outcome after traumatic brain injury in rats

(2009) Ye Xiong et al.   BRAIN RESEARCH

Thymosin-β4 Attenuates Ethanol-induced Neurotoxicity in Cultured Cerebral Cortical Astrocytes by Inhibiting Apoptosis

(2009) Hao Yang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Emerging treatments for traumatic brain injury

(2009) Ye Xiong et al.   EXPERT OPINION ON EMERGING DRUGS

Thymosin β4 Induces Endothelial Progenitor Cell Migration via PI3K/Akt/eNOS Signal Transduction Pathway

(2009) Fu-Yu Qiu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Delayed administration of erythropoietin reducing hippocampal cell loss, enhancing angiogenesis and neurogenesis, and improving functional outcome following traumatic brain injury in rats: comparison of treatment with single and triple dose

(2009) Ye Xiong et al.   JOURNAL OF NEUROSURGERY

Neurological functional recovery after thymosin beta4 treatment in mice with experimental auto encephalomyelitis

(2009) J. Zhang et al.   NEUROSCIENCE

Thymosin beta 4 mRNA and peptide expression in phagocytic cells of different mouse tissues

(2009) Melissa Paulussen et al.   PEPTIDES

Treatment of traumatic brain injury in mice with marrow stromal cells

(2008) Changsheng Qu et al.   BRAIN RESEARCH

Histological and functional outcomes after traumatic brain injury in mice null for the erythropoietin receptor in the central nervous system

(2008) Ye Xiong et al.   BRAIN RESEARCH

Thymosin beta-4 upregulates anti-oxidative enzymes and protects human cornea epithelial cells against oxidative damage

(2008) J H-C Ho et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Mechanisms and Functional Implications of Adult Neurogenesis

(2008) Chunmei Zhao et al.   CELL

Thymosin β4 Is an Essential Paracrine Factor of Embryonic Endothelial Progenitor Cell–Mediated Cardioprotection

(2008) Rabea Hinkel et al.   CIRCULATION

Thymosin beta4 is cytoprotective in human gingival fibroblasts

(2008) Robert Reti et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Basic fibroblast growth factor-enhanced neurogenesis contributes to cognitive recovery in rats following traumatic brain injury

(2008) Dong Sun et al.   EXPERIMENTAL NEUROLOGY

Effects of erythropoietin on reducing brain damage and improving functional outcome after traumatic brain injury in mice

(2008) Ye Xiong et al.   JOURNAL OF NEUROSURGERY

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(2008) Kathryn Beauchamp et al.   MOLECULAR MEDICINE

The Promotive Effects of Thymosin β4 on Neuronal Survival and Neurite Outgrowth by Upregulating L1 Expression

(2008) Hao Yang et al.   NEUROCHEMICAL RESEARCH

Multifunctional drugs for head injury

(2008) Robert Vink et al.   Neurotherapeutics

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL