Pathophysiology in the suprachiasmatic nucleus in mouse models of Huntington’s disease

Alterations of striatal indirect pathway neurons precede motor deficits in two mouse models of Huntington's disease

(2017) Irene Sebastianutto et al.   NEUROBIOLOGY OF DISEASE

Membrane Currents, Gene Expression, and Circadian Clocks

(2017) Charles N. Allen et al.   Cold Spring Harbor Perspectives in Biology

Regulating the Suprachiasmatic Nucleus (SCN) Circadian Clockwork: Interplay between Cell-Autonomous and Circuit-Level Mechanisms

(2017) Erik D. Herzog et al.   Cold Spring Harbor Perspectives in Biology

BK channel inactivation gates daytime excitability in the circadian clock

(2016) Joshua P. Whitt et al.   Nature Communications

Sex Differences in Circadian Dysfunction in the BACHD Mouse Model of Huntington’s Disease

(2016) Dika A. Kuljis et al.   PLoS One

Cardiac Dysfunction in the BACHD Mouse Model of Huntington’s Disease

(2016) Analyne M. Schroeder et al.   PLoS One

Age-related changes in large-conductance calcium-activated potassium channels in mammalian circadian clock neurons

(2015) Sahar Farajnia et al.   NEUROBIOLOGY OF AGING

Dysfunctional Dopaminergic Neurones in Mouse Models of Huntington's Disease: A Role for SK3 Channels

(2015) Glenn M. Dallérac et al.   Neurodegenerative Diseases

Knockout of the BK β2 subunit abolishes inactivation of BK currents in mouse adrenal chromaffin cells and results in slow-wave burst activity

(2014) Pedro L. Martinez-Espinosa et al.   JOURNAL OF GENERAL PHYSIOLOGY

Plasma melatonin is reduced in Huntington's disease

(2014) Eirini Kalliolia et al.   MOVEMENT DISORDERS

Gonadal- and Sex-Chromosome-Dependent Sex Differences in the Circadian System

(2013) Dika A. Kuljis et al.   ENDOCRINOLOGY

Choosing an animal model for the study of Huntington's disease

(2013) Mahmoud A. Pouladi et al.   NATURE REVIEWS NEUROSCIENCE

Behavioral therapy reverses circadian deficits in a transgenic mouse model of Huntington's disease

(2013) Marc Cuesta et al.   NEUROBIOLOGY OF DISEASE

Aging of the Suprachiasmatic Clock

(2013) Sahar Farajnia et al.   NEUROSCIENTIST

The Q175 Mouse Model of Huntington’s Disease Shows Gene Dosage- and Age-Related Decline in Circadian Rhythms of Activity and Sleep

(2013) Dawn H. Loh et al.   PLoS One

How to fix a broken clock

(2013) Analyne M. Schroeder et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Mis-expression of the BK K+ channel disrupts suprachiasmatic nucleus circuit rhythmicity and alters clock-controlled behavior

(2012) Jenna R. Montgomery et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Central and Peripheral Circadian Clocks in Mammals

(2012) Jennifer A. Mohawk et al.   Annual Review of Neuroscience

Circadian and sleep disorder in Huntington's disease

(2012) A. Jennifer Morton   EXPERIMENTAL NEUROLOGY

Evidence for Neuronal Desynchrony in the Aged Suprachiasmatic Nucleus Clock

(2012) S. Farajnia et al.   JOURNAL OF NEUROSCIENCE

Comprehensive Behavioral and Molecular Characterization of a New Knock-In Mouse Model of Huntington’s Disease: zQ175

(2012) Liliana B. Menalled et al.   PLoS One

Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease

(2012) Taneli Heikkinen et al.   PLoS One

Genetic activation of BK currents in vivo generates bidirectional effects on neuronal excitability

(2012) J. R. Montgomery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early Effects of Lipopolysaccharide-Induced Inflammation on Foetal Brain Development in Rat

(2011) Cristina A Ghiani et al.   ASN Neuro

Modulation by the BK accessory β4 subunit of phosphorylation-dependent changes in excitability of dentate gyrus granule neurons

(2011) David Petrik et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Fast Delayed Rectifier Potassium Current: Critical for Input and Output of the Circadian System

(2011) T. Kudo et al.   JOURNAL OF NEUROSCIENCE

Age-Related Decline in Circadian Output

(2011) T. J. Nakamura et al.   JOURNAL OF NEUROSCIENCE

Linking neural activity and molecular oscillations in the SCN

(2011) Christopher S. Colwell   NATURE REVIEWS NEUROSCIENCE

Suprachiasmatic Nucleus: Cell Autonomy and Network Properties

(2010) David K. Welsh et al.   Annual Review of Physiology

Asymptomatic Sleep Abnormalities Are a Common Early Feature in Patients with Huntington’s Disease

(2010) Anna O. G. Goodman et al.   Current Neurology and Neuroscience Reports

Dysfunctions in circadian behavior and physiology in mouse models of Huntington's disease

(2010) Takashi Kudo et al.   EXPERIMENTAL NEUROLOGY

Huntington's disease: from molecular pathogenesis to clinical treatment

(2010) Christopher A Ross et al.   LANCET NEUROLOGY

Sleep and circadian rhythm alterations correlate with depression and cognitive impairment in Huntington's disease

(2010) N. Ahmad Aziz et al.   PARKINSONISM & RELATED DISORDERS

CREB regulation of BK channel gene expression underlies rapid drug tolerance

(2009) Y. Wang et al.   GENES BRAIN AND BEHAVIOR

Delayed onset of the diurnal melatonin rise in patients with Huntington’s disease

(2009) N. Ahmad Aziz et al.   JOURNAL OF NEUROLOGY

Intrinsic, nondeterministic circadian rhythm generation in identified mammalian neurons

(2009) A. B. Webb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Full-Length Human Mutant Huntingtin with a Stable Polyglutamine Repeat Can Elicit Progressive and Selective Neuropathogenesis in BACHD Mice

(2008) M. Gray et al.   JOURNAL OF NEUROSCIENCE

BK Channels Regulate Spontaneous Action Potential Rhythmicity in the Suprachiasmatic Nucleus

(2008) Jack Kent et al.   PLoS One