Article
Biology
Rundong Jiang, Ian Max Andolina, Ming Li, Shiming Tang
Summary: The ventral visual pathway, specifically the V4 area, plays a crucial role in integrating low-level visual features for complex object and scene representations. Neurons in V4 are organized into clustered functional domains selective for shape segments like curves and corners. Stimulus smoothness is identified as the key difference between curve and corner selectivity in V4, indicating the specific population architecture facilitates complex object recognition.
Article
Biology
Ying Zhang, Kenneth E. Schriver, Jia Ming Hu, Anna Wang Roe
Summary: Spatial frequency is an important attribute in the visual scene and how it is encoded in extrastriate areas of primate visual cortex remains unclear. This study used optical imaging to investigate the relationship between spatial frequency maps and visual topography, color, and orientation maps. The findings suggest a population-based spatial frequency organization that is related to color and orientation in different cortical areas.
Article
Computer Science, Artificial Intelligence
Zhaoyang Pang, Callum Biggs O'May, Bhavin Choksi, Rufin VanRullen
Summary: The study shows that incorporating brain-inspired feedback dynamics into convolutional neural networks can improve the perception of illusory contours. This is achieved through pretraining the model on natural image datasets and feedback error correction.
Article
Computer Science, Artificial Intelligence
Atsushi Kodama, Kouji Kimura, Ko Sakai
Summary: The visual area V4 is crucial in the intermediate representation of objects, transforming low-level image features into object-level representations. The estimated intrinsic dimensionality in V4 for local patches generated from natural scenes is approximately 40, which is about half of that reported in IT for whole natural objects. The analysis suggests that V4 has both common and independent representations for contour shapes and/or surfaces with textures, indicating a relatively complex and mixed representation in this intermediate-level area.
Article
Neuroimaging
Toshiyuki Ishioka, Kazumi Hirayama, Yoshiyuki Hosokai, Atsushi Takeda, Kyoko Suzuki, Yoshiyuki Nishio, Yoichi Sawada, Nobuhito Abe, Etsuro Mori
Summary: The study found that patients with Parkinson's disease require longer stimulus durations to perceive Kanizsa illusory figures, which is correlated with hypometabolism in the higher-order visual cortical areas.
NEUROIMAGE-CLINICAL
(2021)
Article
Business
Sercan Sengun, Peter Mawhorter, James Bowie-Wilson, Yusef Audeh, Haewoon Kwak, D. Fox Harrell
Summary: This study examines character design in fighting videogames such as Street Fighter V and Tekken 7, revealing the presence of racism and sexism manifested in stark differences in character design by gender and skin color. The analysis also shows that characters designed in dialogue with developers from their regions of origin are less enfreaked and more positively portrayed, suggesting the potential for implementing anti-bias character designs in popular video games.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2022)
Article
Psychology
Zorana Zupan, Vasilije Gvozdenovic
Summary: The present study aims to evaluate whether contour clarity influences search efficiency of Kanizsa-type illusory contours. Experiment 1 will manipulate contour clarity using inducer size and compare search for a Kanizsa-type illusory target with search for a nonillusory perceptually grouped target. Experiment 2 will manipulate the number of arcs comprising the inducers to examine the effects of contour clarity on visual search. Experiment 3 will compare Kanizsa stimuli formed from smoothed inducers with those used in Experiment 1 to examine the impact of surface alterations on search.
ATTENTION PERCEPTION & PSYCHOPHYSICS
(2023)
Article
Multidisciplinary Sciences
Serena Castellotti, Carlo Francisci, Maria Michela Del Viva
Summary: Pupil responses are influenced by the perception of dynamicity, with real motion inducing larger pupil dilation than implied motion, and illusory motion resulting in the least dilation.
Article
Mathematics
Emilio A. Lauret, Roberto J. Miatello
Summary: This paper investigates the relationship between different K-types in a symmetric space, comparing equivalence and isospectrality between different types. It particularly focuses on p-form representations and shows that in most cases isospectrality implies representation equivalence. An explicit counterexample is also constructed for a specific scenario.
PACIFIC JOURNAL OF MATHEMATICS
(2021)
Article
Physics, Multidisciplinary
Zhao-Lin Liao, Wei-Min Deng, Ze-Liang Xiang, Wen-Jie Chen, Jian-Wen Dong
Summary: In this study, a scheme to engineer the shapes of isofrequency surfaces in metamaterials is proposed based on connection-type wire metamaterials. An equivalent circuit model is developed to analyze the low-frequency dispersion, which demonstrates the ability to achieve different shapes of isofrequency contours by adjusting equivalent circuit parameters.
FRONTIERS IN PHYSICS
(2022)
Article
Multidisciplinary Sciences
Alexandra Krugliak, Alex Clarke
Summary: The study aims to investigate neural processes in real-world environments while maintaining a degree of control over perception by combining mobile EEG and augmented reality (AR) technology. The results demonstrate that cognitively relevant signals can be extracted from mEEG and AR paradigms.
SCIENTIFIC REPORTS
(2022)
Editorial Material
Oncology
Alexander P. Keil
Summary: This article discusses the use of meta-analysis in risk assessment and highlights the importance of exposure studies in sparse literature.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Acoustics
Antonio Pascale, Simona Mancini, Margarida C. Coelho, Claudio Guarnaccia
Summary: This study provides a comprehensive analysis of the noise levels generated during motorsport races by defining two noise indicators: Lap Equivalent Level (LEL) and Race Equivalent Level (REL). The measurements show that REL stabilizes during a race and can be modeled based on the average LEL and the number of vehicles participating. The study offers important information for assessing the exposure of noise-sensitive receivers and reducing noise levels to acceptable levels.
Article
Multidisciplinary Sciences
Kouji Kimura, Atsushi Kodama, Yukako Yamane, Ko Sakai
Summary: Neurons in visual area V4 modulate their responses based on the figure-ground (FG) organization in natural images. This study estimated the spatial extent of local figure and ground regions that evoked FG-dependent responses in neurons. It was found that approximately 50% of the neurons showed effective responses to figure-ground organization, with structures similar to ideal FG-dependent responses. The study also discovered that the extents of the subregions responsive to figure were smaller than those responsive to ground, in agreement with the Gestalt rule. Nonlinear processing was found to contribute to the neural responses, suggesting spatial variance of FG regions.
Article
Multidisciplinary Sciences
Matthew S. Willsey, Samuel R. Nason-Tomaszewski, Scott R. Ensel, Hisham Temmar, Matthew J. Mender, Joseph T. Costello, Parag G. Patil, Cynthia A. Chestek
Summary: Despite the rapid progress and interest in brain-machine interfaces that restore motor function, the study demonstrates that shallow-layer neural network decoders outperform and enable higher velocity finger movements than the current linear decoding standard.
NATURE COMMUNICATIONS
(2022)
Article
Neurosciences
Yang Fang, Ming Chen, Haoran Xu, Peichao Li, Chao Han, Jiaming Hu, Shude Zhu, Heng Ma, Haidong D. Lu
Article
Biochemical Research Methods
Meng Hu, Wu Li, Hualou Liang
IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS
(2018)
Article
Multidisciplinary Sciences
Yin Yan, Li Zhaoping, Wu Li
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2018)
Article
Behavioral Sciences
Fabrice Damon, Zhihan Li, Yin Yan, Wu Li, Kun Guo, Paul C. Quinn, Olivier Pascalis, David Meary
JOURNAL OF COMPARATIVE PSYCHOLOGY
(2019)
Article
Neurosciences
Xiajing Gong, Wu Li, Hualou Liang
JOURNAL OF NEUROPHYSIOLOGY
(2019)
Article
Neurosciences
Kun Guo, Zhihan Li, Yin Yan, Wu Li
EXPERIMENTAL BRAIN RESEARCH
(2019)
Article
Neurosciences
Bor-Shuen Wang, Maria Sol Bernardez Sarria, Xu An, Miao He, Nazia M. Alam, Glen T. Prusky, Michael C. Crair, Z. Josh Huang
Summary: This passage discusses the integration of left and right visual scenes in mammals with binocular vision, focusing on the role of ChCs in V1 and the effects of retinal and callosal activities on their apoptosis, ultimately impacting the development of binocular vision.
Article
Multidisciplinary Sciences
Edward M. Callaway, Hong-Wei Dong, Joseph R. Ecker, Michael J. Hawrylycz, Z. Josh Huang, Ed S. Lein, John Ngai, Pavel Osten, Bing Ren, Andreas Savas Tolias, Owen White, Hongkui Zeng, Xiaowei Zhuang, Giorgio A. Ascoli, M. Margarita Behrens, Jerold Chun, Guoping Feng, James C. Gee, Satrajit S. Ghosh, Yaroslav O. Halchenko, Ronna Hertzano, Byung Kook Lim, Maryann E. Martone, Lydia Ng, Lior Pachter, Alexander J. Ropelewski, Timothy L. Tickle, X. William Yang, Kun Zhang, Trygve E. Bakken, Philipp Berens, Tanya L. Daigle, Julie A. Harris, Nikolas L. Jorstad, Brian E. Kalmbach, Dmitry Kobak, Yang Eric Li, Hanqing Liu, Katherine S. Matho, Eran A. Mukamel, Maitham Naeemi, Federico Scala, Pengcheng Tan, Jonathan T. Ting, Fangming Xie, Meng Zhang, Zhuzhu Zhang, Jingtian Zhou, Brian Zingg, Darren Bertagnolli, Tamara Casper, Kirsten Crichton, Nick Dee, Dinh Diep, Song-Lin Ding, Weixiu Dong, Elizabeth L. Dougherty, Olivia Fong, Melissa Goldman, Jeff Goldy, Rebecca D. Hodge, Lijuan Hu, C. Dirk Keene, Fenna M. Krienen, Matthew Kroll, Blue B. Lake, Kanan Lathia, Sten Linnarsson, Christine S. Liu, Evan Z. Macosko, Steven A. McCarroll, Delissa McMillen, Naeem M. Nadaf, Thuc Nghi Nguyen, Carter R. Palmer, Thanh Pham, Nongluk Plongthongkum, Nora M. Reed, Aviv Regev, Christine Rimorin, William J. Romanow, Steven Savoia, Kimberly Siletti, Kimberly Smith, Josef Sulc, Bosiljka Tasic, Michael Tieu, Amy Torkelson, Herman Tung, Cindy T. J. van Velthoven, Charles R. Vanderburg, Anna Marie Yanny, Rongxin Fang, Xiaomeng Hou, Jacinta D. Lucero, Julia K. Osteen, Antonio Pinto-Duarte, Olivier Poirion, Sebastian Preissl, Xinxin Wang, Andrew Aldridge, Anna Bartlett, Lara Boggeman, Carolyn O'Connor, Rosa G. Castanon, Huaming Chen, Conor Fitzpatrick, Chongyuan Luo, Joseph R. Nery, Michael Nunn, Angeline C. Rivkin, Wei Tian, Bertha Dominguez, Tony Ito-Cole, Matthew Jacobs, Xin Jin, Cheng-Ta Lee, Kuo-Fen Lee, Paula Assakura Miyazaki, Yan Pang, Mohammad Rashid, Jared B. Smith, Minh Vu, Elora Williams, Ethan Armand, Tommaso Biancalani, A. Sina Booeshaghi, Megan Crow, Sandrine Dudoit, Stephan Fischer, Jesse Gillis, Qiwen Hu, Peter Kharchenko, Sheng-Yong Niu, Vasilis Ntranos, Elizabeth Purdom, Davide Risso, Hector Roux de Bezieux, Saroja Somasundaram, Kelly Street, Valentine Svensson, Eeshit Dhaval Vaishnav, Koen Van den Berge, Joshua D. Welch, Zizhen Yao, Xu An, Helen S. Bateup, Ian Bowman, Rebecca K. Chance, Nicholas N. Foster, William Galbavy, Hui Gong, Lin Gou, Joshua T. Hatfield, Houri Hintiryan, Karla E. Hirokawa, Gukhan Kim, Daniel J. Kramer, Anan Li, Xiangning Li, Qingming Luo, Rodrigo Munoz-Castaneda, David A. Stafford, Zhao Feng, Xueyan Jia, Shengdian Jiang, Tao Jiang, Xiuli Kuang, Rachael Larsen, Phil Lesnar, Yaoyao Li, Yuanyuan Li, Lijuan Liu, Hanchuan Peng, Lei Qu, Miao Ren, Zongcai Ruan, Elise Shen, Yuanyuan Song, Wayne Wakeman, Peng Wang, Yimin Wang, Yun Wang, Lulu Yin, Jing Yuan, Sujun Zhao, Xuan Zhao, Arun Narasimhan, Ramesh Palaniswamy, Samik Banerjee, Liya Ding, Dhananjay Huilgol, Bingxing Huo, Hsien-Chi Kuo, Sophie Laturnus, Xu Li, Partha P. Mitra, Judith Mizrachi, Quanxin Wang, Peng Xie, Feng Xiong, Yang Yu, Stephen W. Eichhorn, Jim Berg, Matteo Bernabucci, Yves Bernaerts, Cathryn Rene Cadwell, Jesus Ramon Castro, Rachel Dalley, Leonard Hartmanis, Gregory D. Horwitz, Xiaolong Jiang, Andrew L. Ko, Elanine Miranda, Shalaka Mulherkar, Philip R. Nicovich, Scott F. Owen, Rickard Sandberg, Staci A. Sorensen, Zheng Huan Tan, Shona Allen, Dirk Hockemeyer, Angus Y. Lee, Matthew B. Veldman, Ricky S. Adkins, Seth A. Ament, Hector Corrada Bravo, Robert Carter, Apaala Chatterjee, Carlo Colantuoni, Jonathan Crabtree, Heather Creasy, Victor Felix, Michelle Giglio, Brian R. Herb, Jayaram Kancherla, Anup Mahurkar, Carrie McCracken, Lance Nickel, Dustin Olley, Joshua Orvis, Michael Schor, Greg Hood, Benjamin Dichter, Michael Grauer, Brian Helba, Anita Bandrowski, Nikolaos Barkas, Benjamin Carlin, Florence D. D'Orazi, Kylee Degatano, Thomas H. Gillespie, Farzaneh Khajouei, Kishori Konwar, Carol Thompson, Kathleen Kelly, Stephanie Mok, Susan Sunkin
Summary: This study presents a multimodal cell census and atlas of the mammalian primary motor cortex, integrating various molecular and spatial information to reveal a unified genetic landscape of cortical cell types. The results establish a mechanistic framework of neuronal cell-type organization by linking molecular genetic information with phenotypic properties.
Article
Multidisciplinary Sciences
Rodrigo Munoz-Castaneda, Brian Zingg, Katherine S. Matho, Xiaoyin Chen, Quanxin Wang, Nicholas N. Foster, Anan Li, Arun Narasimhan, Karla E. Hirokawa, Bingxing Huo, Samik Bannerjee, Laura Korobkova, Chris Sin Park, Young-Gyun Park, Michael S. Bienkowski, Uree Chon, Diek W. Wheeler, Xiangning Li, Yun Wang, Maitham Naeemi, Peng Xie, Lijuan Liu, Kathleen Kelly, Xu An, Sarojini M. Attili, Ian Bowman, Anastasiia Bludova, Ali Cetin, Liya Ding, Rhonda Drewes, Florence D'Orazi, Corey Elowsky, Stephan Fischer, William Galbavy, Lei Gao, Jesse Gillis, Peter A. Groblewski, Lin Gou, Joel D. Hahn, Joshua T. Hatfield, Houri Hintiryan, Junxiang Jason Huang, Hideki Kondo, Xiuli Kuang, Philip Lesnar, Xu Li, Yaoyao Li, Mengkuan Lin, Darrick Lo, Judith Mizrachi, Stephanie Mok, Philip R. Nicovich, Ramesh Palaniswamy, Jason Palmer, Xiaoli Qi, Elise Shen, Yu-Chi Sun, Huizhong W. Tao, Wayne Wakemen, Yimin Wang, Shenqin Yao, Jing Yuan, Huiqing Zhan, Muye Zhu, Lydia Ng, Li Zhang, Byung Kook Lim, Michael Hawrylycz, Hui Gong, James C. Gee, Yongsoo Kim, Kwanghun Chung, X. William Yang, Hanchuan Peng, Qingming Luo, Partha P. Mitra, Anthony M. Zador, Hongkui Zeng, Giorgio A. Ascoli, Z. Josh Huang, Pavel Osten, Julie A. Harris, Hong-Wei Dong
Summary: The research team provided a comprehensive cell type-based anatomical description of the mouse primary motor cortex, upper limb area using various cutting-edge technologies. They identified different types of projection neurons and derived an input-output wiring diagram, laying a foundation for future analyses of motor control circuitry in the mammalian brain.
Article
Multidisciplinary Sciences
Katherine S. Matho, Dhananjay Huilgol, William Galbavy, Miao He, Gukhan Kim, Xu An, Jiangteng Lu, Priscilla Wu, Daniela J. Di Bella, Ashwin S. Shetty, Ramesh Palaniswamy, Joshua Hatfield, Ricardo Raudales, Arun Narasimhan, Eric Gamache, Jesse M. Levine, Jason Tucciarone, Eric Szelenyi, Julie A. Harris, Partha P. Mitra, Pavel Osten, Paola Arlotta, Z. Josh Huang
Summary: The study established genetic strategies and tools to dissect and fate-map subpopulations of pyramidal neurons based on their developmental and molecular programs. Through combinatorial strategies, subsets of pyramidal neurons defined by developmental origin, marker expression, anatomical location, and projection targets can be targeted for viral access. These strategies provide an experimental framework for understanding the hierarchical organization and developmental trajectory of subpopulations of pyramidal neurons.
Article
Neurosciences
Xian Zhang, Wuqiang Guan, Tao Yang, Alessandro Furlan, Xiong Xiao, Kai Yu, Xu An, William Galbavy, Charu Ramakrishnan, Karl Deisseroth, Kimberly Ritola, Adam Hantman, Miao He, Z. Josh Huang, Bo Li
Summary: Researchers have discovered two classes of 'hardwired' neurons in the BLA, positive-valence and negative-valence neurons, which express Fezf2 and have distinct connectivity. These neurons drive punishment avoidance and reward seeking behaviors by receiving inputs from separate sensory and limbic areas, and conveying information to the nucleus accumbens and olfactory tubercle.
NATURE NEUROSCIENCE
(2021)
Article
Multidisciplinary Sciences
Guadalupe Astorga, Minggui Chen, Yin Yan, Tiago Siebert Altavini, Caroline S. Jiang, Wu Li, Charles Gilbert
Summary: Neurons in V1 and V4 are adaptive processors influenced by perceptual tasks. They can segment visual scenes and change their tuning according to task-relevant stimulus properties. While V1 represents detailed stimulus characteristics, V4 filters input to provide binary information for two-alternative judgement tasks. Initially, task-relevant information appears in V4 and later in V1, with a 12-ms delay in V4.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Neurosciences
Simon Musall, Xiaonan R. R. Sun, Hemanth Mohan, Xu An, Steven Gluf, Shu-Jing Li, Rhonda Drewes, Emma Cravo, Irene Lenzi, Chaoqun Yin, Bjoern M. Kampa, Anne K. K. Churchland
Summary: Distinct cortical pyramidal neuron types have unique contributions to behavioral decisions. The interactions among diverse cortical and subcortical areas are important for successful decision outcomes. Investigating the cell types that comprise cortical circuits and their dynamics is crucial for understanding complex behavior.
NATURE NEUROSCIENCE
(2023)
Article
Neurosciences
Hemanth Mohan, Xu An, X. Hermione Xu, Hideki Kondo, Shengli Zhao, Katherine S. S. Matho, Bor-Shuen Wang, Simon Musall, Partha Mitra, Z. Josh Huang
Summary: This study reveals that the cellular basis of cerebral cortex functional architecture is not well understood. The activity dynamics of subcortical-projecting and intratelencephalic-projecting neurons in the dorsal cortex of mice during different brain states and behaviors were monitored using genetic targeting and wide-field imaging. The results show that these projection neurons process information and their projection patterns are consistent with their activation patterns.
NATURE NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Yongjun Qian, Jiayun Li, Shengli Zhao, Elizabeth A. Matthews, Michael Adoff, Weixin Zhong, Xu An, Michele Yeo, Christine Park, Xiaolu Yang, Bor-Shuen Wang, Derek G. Southwell, Z. Josh Huang
Summary: CellREADR is a RNA-sensing technology that combines RNA detection with protein translation through RNA editing. It allows specific access to cell types in mice, rats, and human brain tissues, and enables the recording and control of specific types of neurons.