Activation of brain indoleamine 2,3-dioxygenase contributes to epilepsy-associated depressive-like behavior in rats with chronic temporal lobe epilepsy

Depression and temporal lobe epilepsy represent an epiphenomenon sharing similar neural networks: clinical and brain structural evidences

(2013) Kette D. R. Valente et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Expressions of Tumor Necrosis Factor Alpha and MicroRNA-155 in Immature Rat Model of Status Epilepticus and Children with Mesial Temporal Lobe Epilepsy

(2013) Muhammad Usman Ashhab et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Hippocampal gene expression dysregulation of Klotho, nuclear factor kappa B and tumor necrosis factor in temporal lobe epilepsy patients

(2013) Marcelo Teocchi et al.   Journal of Neuroinflammation

The 5-HT1A receptor and 5-HT transporter in temporal lobe epilepsy

(2013) A. Martinez et al.   NEUROLOGY

Novel therapeutic targets in depression: Minocycline as a candidate treatment

(2012) Joanna K. Soczynska et al.   BEHAVIOURAL BRAIN RESEARCH

Interleukin-1β and microRNA-146a in an immature rat model and children with mesial temporal lobe epilepsy

(2012) Ahmed Omran et al.   EPILEPSIA

Depression and epilepsy: Epidemiologic and neurobiologic perspectives that may explain their high comorbid occurrence

(2012) Andres M. Kanner et al.   EPILEPSY & BEHAVIOR

Kynurenines: from the perspective of major psychiatric disorders

(2012) Aye M. Myint   FEBS Journal

Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression

(2012) Hyangin Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

Minocycline attenuates microglia activation and blocks the long-term epileptogenic effects of early-life seizures

(2012) Jayne Abraham et al.   NEUROBIOLOGY OF DISEASE

Depression in epilepsy: A systematic review and meta-analysis

(2012) K. M. Fiest et al.   NEUROLOGY

Neuroinflammation and Depression

(2012) M. Elizabeth Sublette et al.   PSYCHOSOMATIC MEDICINE

Inflammatory changes during epileptogenesis and spontaneous seizures in a mouse model of mesiotemporal lobe epilepsy

(2011) Fabien Pernot et al.   EPILEPSIA

Temporal profiles of age-dependent changes in cytokine mRNA expression and glial cell activation after status epilepticus in postnatal rat hippocampus

(2011) Juha T Järvelä et al.   Journal of Neuroinflammation

Development and validation of an ultra-high performance liquid chromatography–tandem mass-spectrometry (UHPLC–MS/MS) method for the simultaneous determination of neurotransmitters in rat brain samples

(2011) Roberto Romero González et al.   JOURNAL OF NEUROSCIENCE METHODS

ConBr, a Lectin from Canavalia brasiliensis Seeds, Protects Against Quinolinic Acid-Induced Seizures in Mice

(2011) Michael A. Russi et al.   NEUROCHEMICAL RESEARCH

Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression

(2011) Brian Leonard et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Intracerebroventricular administration of inosine is anticonvulsant against quinolinic acid-induced seizures in mice: An effect independent of benzodiazepine and adenosine receptors

(2011) Marcelo Ganzella et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The role of inflammation in epilepsy

(2010) Annamaria Vezzani et al.   Nature Reviews Neurology

The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression

(2010) M. Maes et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Elevated plasma corticosterone level and depressive behavior in experimental temporal lobe epilepsy

(2009) Andrey M. Mazarati et al.   NEUROBIOLOGY OF DISEASE

Comorbidity between epilepsy and depression: Role of hippocampal interleukin-1β

(2009) Andrey M. Mazarati et al.   NEUROBIOLOGY OF DISEASE

Does minocycline have antidepressant effect?

(2008) Chi-Un Pae et al.   BIOMEDICINE & PHARMACOTHERAPY

Depression after status epilepticus: behavioural and biochemical deficits and effects of fluoxetine

(2008) A. Mazarati et al.   BRAIN

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

(2008) J C O'Connor et al.   MOLECULAR PSYCHIATRY

Microglial activation and TNF  production mediate altered CNS excitability following peripheral inflammation

(2008) K. Riazi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA