Article
Green & Sustainable Science & Technology
Clement Cabral, Aghila Sasidharan
Summary: This study examines the impact of corporate governance mechanisms on corporate social performance and finds varying effects of board characteristics and ownership structure on corporate social responsibility in different countries. It supports stewardship theory and agency theory, highlighting the importance of firms' spending on corporate social responsibility activities to protect stakeholders' interests and fulfill their responsibilities towards society.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Multidisciplinary Sciences
Dhurjhoti Saha, Solomon Hailu, Arjan Hada, Junwoo Lee, Jie Luo, Jeff A. Ranish, Yuan-chi Lin, Kyle Feola, Jim Persinger, Abhinav Jain, Bin Liu, Yue Lu, Payel Sen, Blaine Bartholomew
Summary: The SWI/SNF ATP-dependent chromatin remodeler, with its conserved AT-hook domain, is critical for regulating pluripotency, differentiation, and gene transcription. The AT-hook not only anchors chromatin modifiers to DNA but also regulates the intrinsic catalytic activity of SWI/SNF, leading to changes in ATP hydrolysis and nucleosome movement. The AT-hook is essential for SWI/SNF remodeling and activation of specific genes and enhancers in various cells.
NATURE COMMUNICATIONS
(2023)
Article
Plant Sciences
Ana M. Florez-Rueda, Mathias Scharmann, Morgane Roth, Thomas Stadler
Summary: The study on the Arcanum group of wild tomatoes reveals deep genealogical divisions within S. arcanum, with the self-incompatible lineage having close ties to the two self-compatible species. This suggests complex genetic relationships between self-incompatibility and self-compatibility in these species.
FRONTIERS IN PLANT SCIENCE
(2021)
Review
Immunology
Maya Schiller, Tamar L. Ben-Shaanan, Asya Rolls
Summary: This review discusses the regulation of immune responses by the nervous system, focusing on the benefits, mechanisms, and brain areas involved in neuro-immune crosstalk. It highlights how the nervous system influences immunity and explores the communication pathways between the brain and the immune system. The goal is to introduce a conceptual framework for studying these interactions.
NATURE REVIEWS IMMUNOLOGY
(2021)
Article
Psychology, Multidisciplinary
Jin Ai, Ling Yan, Yubei Hu, Yue Liu
Summary: This study investigates how sensory experiences influence visitors' digital engagement with a destination by establishing a strong bond and identification between the destination and tourists. The findings suggest that sensory experiences are critical factors in visitors' bond and identification with a destination, which positively influence their digital engagement behavior on social media.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Engineering, Marine
Zoya A. Tolokonnikova, Dmitry A. Ruban
Summary: The Devonian-Carboniferous transition experienced changes in bryozoan diversity influenced by global events. The diversity patterns recorded in Transcaucasia match those seen globally and in Southern Siberia.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2022)
Article
Microbiology
Ceren Simsek, Victor Max Corman, Hermann Ulrich Everling, Alexander N. Lukashev, Andrea Rasche, Gael Darren Maganga, Tabea Binger, Daan Jansen, Leen Beller, Ward Deboutte, Florian Gloza-Rausch, Antje Seebens-Hoyer, Stoian Yordanov, Augustina Sylverken, Samuel Oppong, Yaw Adu Sarkodie, Peter Vallo, Eric M. Leroy, Mathieu Bourgarel, Kwe Claude Yinda, Marc Van Ranst, Christian Drosten, Jan Felix Drexler, Jelle Matthijnssens
Summary: Research has uncovered a diverse range of rotavirus A strains in bats, with some common bat RVA genotypes linked to atypical RVAs in human and animal populations, suggesting a potentially higher frequency of zoonotic transmission from bat rotaviruses than previously realized.
Article
Plant Sciences
Francesca Giaume, Giulia Ave Bono, Damiano Martignago, Yiling Miao, Giulio Vicentini, Taiyo Toriba, Rui Wang, Dali Kong, Martina Cerise, Daniele Chirivi, Marco Biancucci, Bahman Khahani, Piero Morandini, Wladimir Tameling, Michela Martinotti, Daniela Goretti, George Coupland, Martin Kater, Vittoria Brambilla, Daisuke Miki, Junko Kyozuka, Fabio Fornara
Summary: Many plant species monitor and respond to changes in day length for aligning reproduction with a favourable season. Rice possesses two florigens encoded by Hd3a and RFT1. The arrival of Hd3a and RFT1 at the shoot apical meristem activates FT-L1, which potentiates the effects of Hd3a and RFT1 during panicle development, providing balance and determinacy to the process.
Article
Law
Omri Ben-Shahar
Summary: This article is a case study on the resistance to new market-driven technologies that rely on personal data collection and analysis, even when these technologies create significant social value and save lives. It focuses on tracking devices in cars, which allow auto insurers to monitor policyholders' driving behavior and adjust premiums accordingly. Despite empirical evidence showing that usage-based insurance leads to safer driving and reduces fatal accidents by almost one third, California prohibits this technology and other states limit its effectiveness due to privacy concerns. The article evaluates the justifications for these restrictive regulations in light of the resulting loss of lives and concludes that the social benefits of the tracking technology far outweigh the privacy and related costs.
JOURNAL OF LEGAL ANALYSIS
(2023)
Article
Biology
John F. Deitsch, Sara A. Kaiser
Summary: Artificial light at night alters interspecific interactions between arthropods, increasing predation and parasitism pressure on caterpillars.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2023)
Article
Biodiversity Conservation
Jinshi Xu, Yuhan Zhang, Shiqiang Liu, Yongfu Chai, Han Dang, Ming Yue, Xiao Liu, Yaoxin Guo
Summary: The study investigated six local sites of plant community in Qinling Mountains region and found elevation to be the most important regional-scale environmental predictor of community phylogeny. Taxonomic and phylogenetic diversity showed similar patterns at the regional scale, while diversity at the local scale may differ based on gradients.
ECOLOGICAL INDICATORS
(2021)
Article
Economics
Yuanyuan Cheng, Kerui Du, Xin Yao
Summary: This paper evaluates the impact of the Air Pollution Prevention and Control Action Plan (APPCAP) on the green innovation behavior of listed companies in China. The study finds that stricter emission reduction targets increase the applications for green inventions, and financial resources are essential for promoting green innovation. Broadening financing channels and government subsidies raise the enthusiasm of listed companies to invent. The research also reveals that the companies' green innovation behavior is inconsistent, with APPCAP enhancing green innovation diversity but not improving quality.
Article
Plant Sciences
Ankur Singh, Aryadeep Roychoudhury
Summary: Soil salinity poses a serious threat to global food production, limiting crop growth and yield. Traditional breeding methods are time-consuming and expensive, while genetic engineering is increasingly being used to confer salt tolerance in crops. However, most studies are still limited to the laboratory level, with field trials needed to prove the long-term efficacy of these approaches.
PHYSIOLOGIA PLANTARUM
(2021)
Article
Biochemistry & Molecular Biology
Pengying Hao, David J. Waxman
Summary: In this study, it was found that the absence of STAT5 in mouse liver led to a significant loss of sex bias in gene expression, with male-biased genes being downregulated and female-biased genes being derepressed. The loss of STAT5 binding was directly associated with the downregulation of male-biased genes, while an indirect mechanism was observed for the derepression of female-biased genes.
MOLECULAR AND CELLULAR BIOLOGY
(2021)
Article
Genetics & Heredity
Mai Xu, Lindsey Mehl, Tongwu Zhang, Rohit Thakur, Hayley Sowards, Timothy Myers, Lea Jessop, Alessandra Chesi, Matthew E. Johnson, Andrew D. Wells, Helen T. Michael, Patricia Bunda, Kristine Jones, Herbert Higson, Rebecca C. Hennessey, Ashley Jermusyk, Michael A. Kovacs, Maria Teresa Landi, Mark M. Iles, Alisa M. Goldstein, Jiyeon Choi, Stephen J. Chanock, Struan F. A. Grant, Raj Chari, Glenn Merlino, Matthew H. Law, Kevin M. Brown
Summary: A melanoma-associated locus on chromosome band 7p21.1 has been identified, with rs117132860 as the lead SNP and associated with tanning ability and cutaneous squamous cell carcinoma. Further studies revealed rs117132860 as a functional variant related to AHR gene, altering melanocyte growth phenotypes.
AMERICAN JOURNAL OF HUMAN GENETICS
(2021)
Review
Biochemistry & Molecular Biology
Philip Cowie, Elizabeth A. Hay, Alasdair MacKenzie
EXPERT REVIEWS IN MOLECULAR MEDICINE
(2015)
Article
Genetics & Heredity
S. Davidson, L. Shanley, P. Cowie, M. Lear, P. McGuffin, J. P. Quinn, P. Barrett, A. MacKenzie
PHARMACOGENOMICS JOURNAL
(2016)
Article
Endocrinology & Metabolism
Elizabeth Anne Hay, Abdulla Razak Khalaf, Pietro Marini, Andrew Brown, Karyn Heath, Darrin Sheppard, Alasdair MacKenzie
Editorial Material
Endocrinology & Metabolism
Alasdair MacKenzie, Erika Pinter, John Quinn
Review
Endocrinology & Metabolism
Elizabeth A. Hay, Christopher Knowles, Andreas Kolb, Alasdair MacKenzie
Article
Neurosciences
Domenico Sergi, Amanda C. Morris, Darcy E. Kahn, Fiona H. McLean, Elizabeth A. Hay, Phil Kubitz, Alasdair MacKenzie, Maria G. Martinoli, Janice E. Drew, Lynda M. Williams
NUTRITIONAL NEUROSCIENCE
(2020)
Article
Obstetrics & Gynecology
Paul A. Fowler, Andrew J. Childs, Frederique Courant, Alasdair MacKenzie, Stewart M. Rhind, Jean-Philippe Antignac, Bruno Le Bizec, Panagiotis Filis, Fergus Evans, Samantha Flannigan, Abha Maheshwari, Siladitya Bhattacharya, Ana Monteiro, Richard A. Anderson, Peter J. O'Shaughnessy
HUMAN REPRODUCTION
(2014)
Article
Multidisciplinary Sciences
Colin W. Hay, Irene Hunter, Alasdair MacKenzie, Iain J. McEwan
Article
Endocrinology & Metabolism
Colin W. Hay, Lynne Shanley, Scott Davidson, Philip Cowie, Marissa Lear, Peter McGuffin, Gernot Riedel, Lain J. McEwan, Alasdair MacKenzie
PSYCHONEUROENDOCRINOLOGY
(2014)
Article
Genetics & Heredity
Elizabeth A. Hay, Philip Cowie, Andrew R. McEwan, Ruth Ross, Roger G. Pertwee, Alasdair MacKenzie
Article
Endocrinology & Metabolism
Elizabeth A. Hay, Andrew McEwan, Dana Wilson, Perry Barrett, Giuseppe D'Agostino, Roger G. Pertwee, Alasdair MacKenzie
PSYCHONEUROENDOCRINOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Andrew R. McEwan, Connor Davidson, Elizabeth Hay, Yvonne Turnbull, Johanna Celene Erickson, Pietro Marini, Dana Wilson, Andrew M. McIntosh, Mark J. Adams, Chris Murgatroyd, Perry Barrett, Mirela Delibegovic, Toni-Kim Clarke, Alasdair MacKenzie
Summary: This study identified a significant interaction between allelic variation of the human GAL5.1 gene, alcohol intake, and anxiety in men, using human association analysis. Disruption of GAL5.1 in mice resulted in reduced ethanol intake and anxiety-like behavior in male animals. The EGR1 transcription factor was found to be important in the activity of the GG genotype of GAL5.1 in amygdala and hypothalamus.
MOLECULAR PSYCHIATRY
(2021)
Article
Biochemistry & Molecular Biology
Andrew R. McEwan, Alasdair MacKenzie
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Biochemistry & Molecular Biology
Andrew McEwan, Johanna Celene Erickson, Connor Davidson, Jenny Heijkoop, Yvonne Turnbull, Mirela Delibegovic, Christopher Murgatroyd, Alasdair MacKenzie
Summary: Excessive maternal fat intake and obesity can increase susceptibility of offspring to conditions like chronic anxiety and substance abuse. This study suggests that environmental factors can influence DNA methylation changes in regulatory regions of the genome, impacting behaviors related to anxiety and alcohol intake. Results showed that early life stress did not significantly affect DNA methylation levels within GAL5.1, but exposure of pregnant mothers to high-fat diet had a notable effect on DNA methylation levels within GAL5.1 in specific brain regions of male offspring. Further studies indicated that DNA methylation plays a repressive role on GAL5.1 activity and response to stimuli, while disrupting GAL5.1 from the genome resulted in decreased intake of high-fat diet, highlighting its potential role in regulating behaviors influenced by environmental factors like diet. This suggests a possible mechanism linking maternal high-fat diet with transgenerational susceptibility to alcohol abuse and anxiety through epigenetic regulation.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Pietro Marini, Philip Cowie, Ahmet Ayar, Guy S. S. Bewick, John Barrow, Roger G. G. Pertwee, Alasdair MacKenzie, Paolo Tucci
Summary: In this study, the researchers investigated the mechanism of CB1/M-3 receptor cross-talk using SH-SY5Y cells as a model system. They found that M-3 receptor activation upregulates the CNR1 gene, leading to a more potent CB1 receptor response. Calcium homeostasis plays a crucial role in this cross-talk. The co-expression of M-3 and CB1 receptors in specific brain areas suggests their involvement in altered synaptic plasticity after exposure to cannabinoids, and highlights the potential of targeting the M-3 receptor in drug development and understanding response variation to cannabinoids.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)