PET imaging in multiple sclerosis

In Vivo Imaging of Brain Estrogen Receptors in Rats: A 16 -18F-Fluoro-17 -Estradiol PET Study

(2014) M. A. Khayum et al.   JOURNAL OF NUCLEAR MEDICINE

Initial Evaluation of 18F-GE-179, a Putative PET Tracer for Activated N-Methyl D-Aspartate Receptors

(2014) C. J. McGinnity et al.   JOURNAL OF NUCLEAR MEDICINE

Clinical and biomarker assessment of demyelinating events suggesting multiple sclerosis

(2013) A. Gajofatto et al.   ACTA NEUROLOGICA SCANDINAVICA

Longitudinal positron emission tomography imaging for monitoring myelin repair in the spinal cord

(2013) Chunying Wu et al.   ANNALS OF NEUROLOGY

Multiple sclerosis lymphocytes upregulate A2Aadenosine receptors that are antiinflammatory when stimulated

(2013) Fabrizio Vincenzi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Adenosine A2A Receptors in Secondary Progressive Multiple Sclerosis: A [11C]TMSX Brain PET Study

(2013) Eero Rissanen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cannabinoid Receptor 2: Potential Role in Immunomodulation and Neuroinflammation

(2013) Slava Rom et al.   Journal of Neuroimmune Pharmacology

Estrogen receptor-β ligand treatment after disease onset is neuroprotective in the multiple sclerosis model

(2013) Amy J. Wisdom et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Central Nervous System Expression and PET Imaging of the Translocator Protein in Relapsing-Remitting Experimental Autoimmune Encephalomyelitis

(2013) F. Mattner et al.   JOURNAL OF NUCLEAR MEDICINE

LXR Agonists: New Potential Therapeutic Drug for Neurodegenerative Diseases

(2013) Pei Xu et al.   MOLECULAR NEUROBIOLOGY

Radiolabeled COX-2 Inhibitors for Non-Invasive Visualization of COX-2 Expression and Activity — A Critical Update

(2013) Markus Laube et al.   MOLECULES

Estrogen receptor β ligand therapy activates PI3K/Akt/mTOR signaling in oligodendrocytes and promotes remyelination in a mouse model of multiple sclerosis

(2013) Shalini Kumar et al.   NEUROBIOLOGY OF DISEASE

Increased ventral striatal CB1 receptor binding is related to negative symptoms in drug-free patients with schizophrenia

(2013) Jenny Ceccarini et al.   NEUROIMAGE

PET imaging of demyelination and remyelination in the cuprizone mouse model for multiple sclerosis: A comparison between [11C]CIC and [11C]MeDAS

(2013) Daniele de Paula Faria et al.   NEUROIMAGE

Therapeutic potential of a novel cannabinoid agent CB52 in the mouse model of experimental autoimmune encephalomyelitis

(2013) R. Ribeiro et al.   NEUROSCIENCE

PET Imaging of Inflammation Biomarkers

(2013) Chenxi Wu et al.   Theranostics

In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [18F]FEDAA1106

(2013) Akihiro Takano et al.   EJNMMI Research

Personalized medicine in multiple sclerosis: hope or reality?

(2012) Tobias Derfuss   BMC Medicine

Neurodegeneration in multiple sclerosis: novel treatment strategies

(2012) Felix Luessi et al.   Expert Review of Neurotherapeutics

A Genetic Polymorphism for Translocator Protein 18 Kda Affects both in Vitro and in Vivo Radioligand Binding in Human Brain to this Putative Biomarker of Neuroinflammation

(2012) William C Kreisl et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Structural and Metabolic Features of Two Different Variants of Multiple Sclerosis: A PET/MRI Study

(2012) Julie Bolcaen et al.   JOURNAL OF NEUROIMAGING

Imaging Microglial/Macrophage Activation in Spinal Cords of Experimental Autoimmune Encephalomyelitis Rats by Positron Emission Tomography Using the Mitochondrial 18 kDa Translocator Protein Radioligand [18F]DPA-714

(2012) G. Abourbeh et al.   JOURNAL OF NEUROSCIENCE

18F-FDG PET Detects Inflammatory Infiltrates in Spinal Cord Experimental Autoimmune Encephalomyelitis Lesions

(2012) D. Buck et al.   JOURNAL OF NUCLEAR MEDICINE

Inflammation inhibits GABA transmission in multiple sclerosis

(2012) Silvia Rossi et al.   Multiple Sclerosis Journal

Will the real multiple sclerosis please stand up?

(2012) Peter K. Stys et al.   NATURE REVIEWS NEUROSCIENCE

Increased PK11195 PET binding in the cortex of patients with MS correlates with disability

(2012) M. Politis et al.   NEUROLOGY

Principles of Nuclear Medicine Imaging: Planar, SPECT, PET, Multi-modality, and Autoradiography Systems

(2012) Pat Zanzonico   RADIATION RESEARCH

Pathology of Demyelinating Diseases

(2011) Bogdan F.Gh. Popescu et al.   Annual Review of Pathology-Mechanisms of Disease

Glutamate NMDA receptor dysregulation in Parkinson’s disease with dyskinesias

(2011) Imtiaz Ahmed et al.   BRAIN

Fluorinated COX-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer

(2011) M. J. Uddin et al.   Cancer Prevention Research

Role of Cannabinoids in Multiple Sclerosis

(2011) John P. Zajicek et al.   CNS DRUGS

The molecular basis of neurodegeneration in multiple sclerosis

(2011) Hans Lassmann et al.   FEBS LETTERS

Pregnancy and Multiple Sclerosis

(2011) Mari Stuart et al.   JOURNAL OF MIDWIFERY & WOMENS HEALTH

[11C]DAC-PET for Noninvasively Monitoring Neuroinflammation and Immunosuppressive Therapy Efficacy in Rat Experimental Autoimmune Encephalomyelitis Model

(2011) Lin Xie et al.   Journal of Neuroimmune Pharmacology

Decreased microglial activation in MS patients treated with glatiramer acetate

(2011) John N. Ratchford et al.   JOURNAL OF NEUROLOGY

Liver X receptors regulate cholesterol homeostasis in oligodendrocytes

(2011) Katherine Nelissen et al.   JOURNAL OF NEUROSCIENCE RESEARCH

In Vivo Expression of Cyclooxygenase-1 in Activated Microglia and Macrophages During Neuroinflammation Visualized by PET with 11C-Ketoprofen Methyl Ester

(2011) M. Shukuri et al.   JOURNAL OF NUCLEAR MEDICINE

Cerebral acetylcholinesterase activity is not decreased in MS patients with cognitive impairment

(2011) Jere R Virta et al.   Multiple Sclerosis Journal

Positron emission tomography with 11C-flumazenil in the rat shows preservation of binding sites during the acute phase after 2h-transient focal ischemia

(2011) S. Rojas et al.   NEUROSCIENCE

Neuroprotection mediated through estrogen receptor-  in astrocytes

(2011) R. D. Spence et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MR Imaging of Multiple Sclerosis

(2011) Massimo Filippi et al.   RADIOLOGY

Imaging central nervous system myelin by positron emission tomography in multiple sclerosis using [methyl-11C]-2-(4′-methylaminophenyl)- 6-hydroxybenzothiazole

(2010) Bruno Stankoff et al.   ANNALS OF NEUROLOGY

A novel PET marker for in vivo quantification of myelination

(2010) Chunying Wu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Role of MRI in diagnosis and treatment of multiple sclerosis

(2010) Mohammad Ali Sahraian et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Basics and principles of radiopharmaceuticals for PET/CT

(2010) W. Wadsak et al.   EUROPEAN JOURNAL OF RADIOLOGY

A synthetic cannabinoid agonist promotes oligodendrogliogenesis during viral encephalitis in rats

(2010) Marylou V. Solbrig et al.   EXPERIMENTAL NEUROLOGY

The constitutive production of the endocannabinoid 2-arachidonoylglycerol participates in oligodendrocyte differentiation

(2010) Oscar Gomez et al.   GLIA

Translocator Protein PET Imaging for Glial Activation in Multiple Sclerosis

(2010) Unsong Oh et al.   Journal of Neuroimmune Pharmacology

Cyclooxygenase-2 expression in oligodendrocytes increases sensitivity to excitotoxic death

(2010) Noel G Carlson et al.   Journal of Neuroinflammation

αB-Crystallin Is a Target for Adaptive Immune Responses and a Trigger of Innate Responses in Preactive Multiple Sclerosis Lesions

(2010) Johannes M. van Noort et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

PET and SPECT Imaging of the NMDA Receptor System: An Overview of Radiotracer Development

(2010) F. Sobrio et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Benefits and Risks of Postmenopausal Hormone Therapy When It Is Initiated Soon After Menopause

(2009) Ross L. Prentice et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Rituximab in patients with primary progressive multiple sclerosis: Results of a randomized double-blind placebo-controlled multicenter trial

(2009) Kathleen Hawker et al.   ANNALS OF NEUROLOGY

Adenosine A1 receptors using 8-dicyclopropylmethyl-1-[11C]methyl-3-propylxanthine PET in Alzheimer’s disease

(2009) Nobuyoshi Fukumitsu et al.   ANNALS OF NUCLEAR MEDICINE

In Vivo Quantification of Myelin Changes in the Vertebrate Nervous System

(2009) Y. Wang et al.   JOURNAL OF NEUROSCIENCE

Characterization of PiB Binding to White Matter in Alzheimer Disease and Other Dementias

(2009) M. T. Fodero-Tavoletti et al.   JOURNAL OF NUCLEAR MEDICINE

Development and Characterization of Clinical-Grade 89Zr-Trastuzumab for HER2/neu ImmunoPET Imaging

(2009) E. C.F. Dijkers et al.   JOURNAL OF NUCLEAR MEDICINE

Adenosine A2A receptor mediates microglial process retraction

(2009) Anna G Orr et al.   NATURE NEUROSCIENCE

Synthesis and biological evaluation of carbon-11- and fluorine-18-labeled 2-oxoquinoline derivatives for type 2 cannabinoid receptor positron emission tomography imaging

(2009) Nele Evens et al.   NUCLEAR MEDICINE AND BIOLOGY

Monoclonal antibody treatments for multiple sclerosis

(2008) John W. Rose et al.   Current Neurology and Neuroscience Reports

PET Imaging of the Peripheral Benzodiazepine Receptor: Monitoring Disease Progression and Therapy Response in Neurodegenerative Disorders

(2008) Janine Doorduin et al.   CURRENT PHARMACEUTICAL DESIGN

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

Brain Imaging of Multiple Sclerosis: the Next 10 Years

(2008) Paul M. Matthews   NEUROIMAGING CLINICS OF NORTH AMERICA

Can celecoxib affect P-glycoprotein-mediated drug efflux? A microPET study

(2008) Erik F.J. de Vries et al.   NUCLEAR MEDICINE AND BIOLOGY

Glucocorticoids regulate innate immunity in a model of multiple sclerosis: reciprocal interactions between the A1 adenosine receptor and β-arrestin-1 in monocytoid cells

(2007) Shigeki Tsutsui et al.   FASEB JOURNAL

Functional neuroimaging in multiple sclerosis with radiolabelled glia markers: Preliminary comparative PET studies with [11C]vinpocetine and [11C]PK11195 in patients

(2007) Ádám Vas et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Gender-dependent increases with healthy aging of the human cerebral cannabinoid-type 1 receptor binding using [18F]MK-9470 PET

(2007) Koen Van Laere et al.   NEUROIMAGE

Evaluation of [11C]rofecoxib as PET tracer for cyclooxygenase 2 overexpression in rat models of inflammation

(2007) Erik F.J. de Vries et al.   NUCLEAR MEDICINE AND BIOLOGY