Epigenetic Modification of the FoxP3 TSDR in HAM/TSP Decreases the Functional Suppression of Tregs

Regulatory T cells in cancer: An overview and perspectives on Cyclooxygenase-2 and Foxp3 DNA methylation

(2013) Mehmet Sahin et al.   HUMAN IMMUNOLOGY

Humoral immune response to HTLV-1 basic leucine zipper factor (HBZ) in HTLV-1-infected individuals

(2013) Yoshimi Enose-Akahata et al.   Retrovirology

Loss of Epigenetic Modification Driven by the Foxp3 Transcription Factor Leads to Regulatory T Cell Insufficiency

(2012) Matthew L. Bettini et al.   IMMUNITY

Demethylation analysis of the FOXP3 locus shows quantitative defects of regulatory T cells in IPEX-like syndrome

(2012) F. Barzaghi et al.   JOURNAL OF AUTOIMMUNITY

Antiretroviral activity of 5-azacytidine during treatment of a HTLV-1 positive myelodysplastic syndrome with autoimmune manifestations

(2012) Panagiotis T Diamantopoulos et al.   Virology Journal

HTLV Tax: A Fascinating Multifunctional Co-Regulator of Viral and Cellular Pathways

(2012) Robert Currer et al.   Frontiers in Microbiology

Targeting the right regulatory T-cell population for tumor immunotherapy

(2012) Vivian L. Weiss et al.   OncoImmunology

Kinetics and intracellular compartmentalization of HTLV-1 gene expression: nuclear retention of HBZ mRNAs

(2011) F. Rende et al.   BLOOD

Effects of valproate on Tax and HBZ expression in HTLV-1 and HAM/TSP T lymphocytes

(2011) G. Belrose et al.   BLOOD

Isolation strategies of regulatory T cells for clinical trials: Phenotype, function, stability, and expansion capacity

(2011) Sya N. Ukena et al.   EXPERIMENTAL HEMATOLOGY

Single-Cell Analysis of the Human T Regulatory Population Uncovers Functional Heterogeneity and Instability within FOXP3+ Cells

(2011) E. d'Hennezel et al.   JOURNAL OF IMMUNOLOGY

To Be or Not to Be a Treg Cell: Lineage Decisions Controlled by Epigenetic Mechanisms

(2011) A. Toker et al.   Science Signaling

HTLV-1 bZIP Factor Induces T-Cell Lymphoma and Systemic Inflammation In Vivo

(2011) Yorifumi Satou et al.   PLoS Pathogens

Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells

(2010) Julia K. Polansky et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

T Regulatory Cells in Cord Blood—FOXP3 Demethylation as Reliable Quantitative Marker

(2010) Jing Liu et al.   PLoS One

Epigenetic mechanisms of regulation of Foxp3 expression

(2009) G. Lal et al.   BLOOD

Comparison of stable human Treg and Th clones by transcriptional profiling

(2009) Julie Stockis et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Treatment with bortezomib of human CD4+ T cells preserves natural regulatory T cells and allows the emergence of a distinct suppressor T-cell population

(2009) B. Blanco et al.   HAEMATOLOGICA

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Induction of Foxp3 demethylation increases regulatory CD4+CD25+ T cells and prevents the occurrence of diabetes in mice

(2009) Qanhui Zheng et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Abnormally High Levels of Virus-Infected IFN-γ+CCR4+CD4+CD25+ T Cells in a Retrovirus-Associated Neuroinflammatory Disorder

(2009) Yoshihisa Yamano et al.   PLoS One

Dysregulation of TGF-  signaling and regulatory and effector T-cell function in virus-induced neuroinflammatory disease

(2008) C. Grant et al.   BLOOD

The frequency of CD127low expressing CD4+CD25high T regulatory cells is inversely correlated with human T lymphotrophic virus type-1 (HTLV-1) proviral load in HTLV-1-infection and HTLV-1-associated myelopathy/tropical spastic paraparesis

(2008) Jakob Michaëlsson et al.   BMC IMMUNOLOGY

DNA methylation controls Foxp3 gene expression

(2008) Julia K. Polansky et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

FOXP3 Promoter Demethylation Reveals the Committed Treg Population in Humans

(2008) Peter C. J. Janson et al.   PLoS One