Targeting the right regulatory T-cell population for tumor immunotherapy

Trafficking of High Avidity HER-2/neu-Specific T Cells into HER-2/neu-Expressing Tumors after Depletion of Effector/Memory-Like Regulatory T Cells

(2012) Vivian L. Weiss et al.   PLoS One

Monoclonal antibody blockade of IL-2 receptor   during lymphopenia selectively depletes regulatory T cells in mice and humans

(2011) D. A. Mitchell et al.   BLOOD

Nondominant CD8 T Cells Are Active Players in the Vaccine-Induced Antitumor Immune Response

(2011) Jennifer N. Uram et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cell Vaccination in Combination with Anti-CD25 Monoclonal Antibody Treatment: A Phase I/II Study in Metastatic Melanoma Patients

(2010) J. F. M. Jacobs et al.   CLINICAL CANCER RESEARCH

Effective Depletion of Regulatory T Cells Allows the Recruitment of Mesothelin-Specific CD8+T Cells to the Antitumor Immune Response Against a Mesothelin-Expressing Mouse Pancreatic Adenocarcinoma

(2008) Ihid C. Leao et al.   CTS-Clinical and Translational Science

Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma

(2008) Sergio A. Quezada et al.   JOURNAL OF EXPERIMENTAL MEDICINE