Potassium Channels in Drosophila: Historical Breakthroughs, Significance, and Perspectives

Frequent aberrant expression of the human ether à go-go (hEAG1) potassium channel in head and neck cancer: pathobiological mechanisms and clinical implications

(2012) Sofía Tirados Menéndez et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Contribution of EAG to excitability and potassium currents in Drosophila larval motoneurons

(2012) Subhashini Srinivasan et al.   JOURNAL OF NEUROPHYSIOLOGY

Ultra-rapid delayed rectifier channels: molecular basis and therapeutic implications

(2011) U. Ravens et al.   CARDIOVASCULAR RESEARCH

Drosophila, Genetic Screens, and Cardiac Function

(2011) Matthew J. Wolf et al.   CIRCULATION RESEARCH

Drosophila as a model of wound healing and tissue regeneration in vertebrates

(2011) Yaiza Belacortu et al.   DEVELOPMENTAL DYNAMICS

Transient outward current (Ito) gain-of-function mutations in the KCND3-encoded Kv4.3 potassium channel and Brugada syndrome

(2011) John R. Giudicessi et al.   HEART RHYTHM

Contribution of Kv1.2 Voltage-gated Potassium Channel to D2 Autoreceptor Regulation of Axonal Dopamine Overflow

(2011) Stephanie Fulton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemical genetics and drug screening in Drosophila cancer models

(2011) Mara Gladstone et al.   Journal of Genetics and Genomics

Model Organisms Reveal Insight into Human Neurodegenerative Disease: Ataxin-2 Intermediate-Length Polyglutamine Expansions Are a Risk Factor for ALS

(2011) Nancy M. Bonini et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Altered gene regulation and synaptic morphology in Drosophila learning and memory mutants

(2011) Z. Guan et al.   LEARNING & MEMORY

Shal/Kv4 Channels Are Required for Maintaining Excitability during Repetitive Firing and Normal Locomotion in Drosophila

(2011) Yong Ping et al.   PLoS One

Drosophila KCNQ Channel Displays Evolutionarily Conserved Electrophysiology and Pharmacology with Mammalian KCNQ Channels

(2011) Sonia Cavaliere et al.   PLoS One

Drosophila as a genetic model for studying pathogenic human viruses

(2011) Tamara T. Hughes et al.   VIROLOGY

Eag and HERG potassium channels as novel therapeutic targets in cancer

(2011) Viren Asher et al.   World Journal of Surgical Oncology

Understanding Forkhead Box Class O Function: Lessons from Drosophila melanogaster

(2010) Oscar Puig et al.   ANTIOXIDANTS & REDOX SIGNALING

The Q System: A Repressible Binary System for Transgene Expression, Lineage Tracing, and Mosaic Analysis

(2010) Christopher J. Potter et al.   CELL

Lymphocyte activation in type 1 diabetes mellitus: The increased significance of Kv1.3 potassium channels

(2010) Gergely Toldi et al.   IMMUNOLOGY LETTERS

The Beneficial Effect of Blocking Kv1.3 in the Psoriasiform SCID Mouse Model

(2010) Amos Gilhar et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Orchestration of Stepwise Synaptic Growth by K+ and Ca2+ Channels in Drosophila

(2010) J. Lee et al.   JOURNAL OF NEUROSCIENCE

A Drosophila behavioral mutant, down and out (dao), is defective in an essential regulator of Erg potassium channels

(2010) T. Fergestad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus

(2010) A. V. Tzingounis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A genetic mosaic approach for neural circuit mapping in Drosophila

(2010) R. A. Bohm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular determinants of cardiac transient outward potassium current (Ito) expression and regulation

(2009) Noriko Niwa et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Shaker and Shal Mediate Transient Calcium-Independent Potassium Current in a Drosophila Flight Motoneuron

(2009) Stefanie Ryglewski et al.   JOURNAL OF NEUROPHYSIOLOGY

NAD+ Activates KNa Channels in Dorsal Root Ganglion Neurons

(2009) T. J. Tamsett et al.   JOURNAL OF NEUROSCIENCE

A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia

(2009) Stephen J Huffaker et al.   NATURE MEDICINE

Ion channels to inactivate neurons in Drosophila

(2009) James J. L. Hodge   Frontiers in Molecular Neuroscience

Transcriptional profiling of ion channel genes in Brugada syndrome and other right ventricular arrhythmogenic diseases

(2008) Nathalie Gaborit et al.   EUROPEAN HEART JOURNAL

Glutathione Depletion and Disruption of Intracellular Ionic Homeostasis Regulate Lymphoid Cell Apoptosis

(2008) Rodrigo Franco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative splicing of the eag potassium channel gene in Drosophila generates a novel signal transduction scaffolding protein

(2008) Xiu Xia Sun et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Ventricular Arrhythmias after Left Ventricular Assist Device Implantation

(2008) MARWAN REFAAT et al.   PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY

The hERG K+ channel: target and antitarget strategies in drug development

(2008) Emanuel Raschi et al.   PHARMACOLOGICAL RESEARCH

The hERG potassium channel and hERG screening for drug-induced torsades de pointes

(2008) Jules C. Hancox et al.   PHARMACOLOGY & THERAPEUTICS

Function of the Shaw Potassium Channel within the Drosophila Circadian Clock

(2008) James J. Hodge et al.   PLoS One

From bench to drug: Human seizure modeling using Drosophila

(2007) J SONG et al.   PROGRESS IN NEUROBIOLOGY