Primary glioblastoma cultures: can profiling of stem cell markers predict radiotherapy sensitivity?

PDGF-B Can Sustain Self-renewal and Tumorigenicity of Experimental Glioma-Derived Cancer-Initiating Cells by Preventing Oligodendrocyte Differentiation

(2015) Yiwen Jiang et al.   NEOPLASIA

Targeting Self-Renewal in High-Grade Brain Tumors Leads to Loss of Brain Tumor Stem Cells and Prolonged Survival

(2014) Zhe Zhu et al.   Cell Stem Cell

Malignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collective

(2013) B. Wiestler et al.   NEURO-ONCOLOGY

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

(2012) Dominik Sturm et al.   CANCER CELL

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Cancer stem cells and survival pathways

(2011) Dolores Hambardzumyan et al.   CELL CYCLE

Costimulatory Protein 4IgB7H3 Drives the Malignant Phenotype of Glioblastoma by Mediating Immune Escape and Invasiveness

(2011) D. Lemke et al.   CLINICAL CANCER RESEARCH

SOX2-RNAi attenuates S-phase entry and induces RhoA-dependent switch to protease-independent amoeboid migration in human glioma cells

(2011) Felix Oppel et al.   Molecular Cancer

The presence of stem cell marker-expressing cells is not prognostically significant in glioblastomas

(2011) Kyung-Jung Kim et al.   NEUROPATHOLOGY

Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions

(2011) J D Lathia et al.   Cell Death & Disease

Glioblastoma Stem-Like Cells—Biology and Therapeutic Implications

(2011) Demirkan B. Gürsel et al.   Cancers

A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2α

(2010) Sascha Seidel et al.   BRAIN

A Hierarchy of Self-Renewing Tumor-Initiating Cell Types in Glioblastoma

(2010) Ruihuan Chen et al.   CANCER CELL

PLAGL2 Regulates Wnt Signaling to Impede Differentiation in Neural Stem Cells and Gliomas

(2010) Hongwu Zheng et al.   CANCER CELL

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

CD44 Attenuates Activation of the Hippo Signaling Pathway and Is a Prime Therapeutic Target for Glioblastoma

(2010) Y. Xu et al.   CANCER RESEARCH

Transcriptional Profiles of CD133+ and CD133- Glioblastoma-Derived Cancer Stem Cell Lines Suggest Different Cells of Origin

(2010) C. Lottaz et al.   CANCER RESEARCH

NO Signals from the Cancer Stem Cell Niche

(2010) Joan Seoane   Cell Stem Cell

Molecular signatures classify astrocytic gliomas byIDH1mutation status

(2010) Grischa Toedt et al.   INTERNATIONAL JOURNAL OF CANCER

Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells

(2010) Lucia Ricci-Vitiani et al.   NATURE

Quantitation of human mammary epithelial stem cells with in vivo regenerative properties using a subrenal capsule xenotransplantation assay

(2010) Peter Eirew et al.   Nature Protocols

Aldehyde dehydrogenase 1 positive glioblastoma cells show brain tumor stem cell capacity

(2010) M. Rasper et al.   NEURO-ONCOLOGY

WHO grade-specific comparative genomic hybridization pattern of astrocytoma – A meta-analysis

(2010) Heidrun Holland et al.   PATHOLOGY RESEARCH AND PRACTICE

Isolation of cancer stem-like cells from a side population of a human glioblastoma cell line, SK-MG-1

(2009) Raita Fukaya et al.   CANCER LETTERS

EZH2 Is Essential for Glioblastoma Cancer Stem Cell Maintenance

(2009) M.-L. Suva et al.   CANCER RESEARCH

Autocrine TGF-β Signaling Maintains Tumorigenicity of Glioma-Initiating Cells through Sry-Related HMG-Box Factors

(2009) Hiroaki Ikushima et al.   Cell Stem Cell

Toll-Like Receptor Engagement Enhances the Immunosuppressive Properties of Human Bone Marrow-Derived Mesenchymal Stem Cells by Inducing Indoleamine-2,3-dioxygenase-1 via Interferon-β and Protein Kinase R

(2009) Christiane A. Opitz et al.   STEM CELLS

Neurosphere Formation Is an Independent Predictor of Clinical Outcome in Malignant Glioma

(2009) Dan R. Laks et al.   STEM CELLS

Epigenetic-Mediated Dysfunction of the Bone Morphogenetic Protein Pathway Inhibits Differentiation of Glioblastoma-Initiating Cells

(2008) Jeongwu Lee et al.   CANCER CELL

Temozolomide Preferentially Depletes Cancer Stem Cells in Glioblastoma

(2008) D. Beier et al.   CANCER RESEARCH

Targeting Cancer Stem Cells through L1CAM Suppresses Glioma Growth

(2008) S. Bao et al.   CANCER RESEARCH

Partial Biological Characterization of Cancer Stem-like Cell Line (WJ2) of Human Glioblastoma Multiforme

(2008) Jing Wang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo

(2008) D. Hambardzumyan et al.   GENES & DEVELOPMENT

Presence of pluripotent CD133+ cells correlates with malignancy of gliomas

(2008) Niklas Thon et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Regulation of Self-Renewal and Pluripotency by Sox2 in Human Embryonic Stem Cells

(2008) Helen Fong et al.   STEM CELLS

SOX2Silencing in Glioblastoma Tumor-Initiating Cells Causes Stop of Proliferation and Loss of Tumorigenicity

(2008) Rosaria Maria Rita Gangemi et al.   STEM CELLS