HIV-1 protein Tat produces biphasic changes in NMDA-evoked increases in intracellular Ca2+concentration via activation of Src kinase and nitric oxide signaling pathways

Targeting the Glutamatergic System for the Treatment of HIV-Associated Neurocognitive Disorders

(2013) Michelle C. Potter et al.   Journal of Neuroimmune Pharmacology

Human Immunodeficiency Virus-1 Tat Protein Increases the Number of Inhibitory Synapses between Hippocampal Neurons in Culture

(2013) N. J. Hargus et al.   JOURNAL OF NEUROSCIENCE

Detection of anti-tat antibodies in CSF of individuals with HIV-associated neurocognitive disorders

(2013) M. Bachani et al.   JOURNAL OF NEUROVIROLOGY

LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype

(2013) Wladislaw Maier et al.   Molecular Neurodegeneration

Enhancement by Interleukin-1β of AMPA and NMDA Receptor-Mediated Currents in Adult Rat Spinal Superficial Dorsal Horn Neurons

(2013) Tao Liu et al.   Molecular Pain

Opposite Roles of NMDA Receptors in Relapsing and Primary Progressive Multiple Sclerosis

(2013) Silvia Rossi et al.   PLoS One

Role of Endolysosomes in HIV-1 Tat-Induced Neurotoxicity

(2012) Liang Hui et al.   ASN Neuro

Role of the N-methyl-d-aspartate receptors complex in amyotrophic lateral sclerosis

(2012) Alida Spalloni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Synaptic Dysfunction in the Hippocampus Accompanies Learning and Memory Deficits in Human Immunodeficiency Virus Type-1 Tat Transgenic Mice

(2012) Sylvia Fitting et al.   BIOLOGICAL PSYCHIATRY

Glutamate Binding to the GluN2B Subunit Controls Surface Trafficking ofN-Methyl-d-aspartate (NMDA) Receptors

(2012) Kevin She et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epileptiform stimulus increases Homer 1a expression to modulate synapse number and activity in hippocampal cultures

(2012) Yan Li et al.   JOURNAL OF NEUROPHYSIOLOGY

Epileptic stimulus increases Homer 1a expression to modulate endocannabinoid signaling in cultured hippocampal neurons

(2012) Yan Li et al.   NEUROPHARMACOLOGY

Expression of HIV-Tat protein is associated with learning and memory deficits in the mouse

(2011) Amanda N. Carey et al.   BEHAVIOURAL BRAIN RESEARCH

Subtype selective NMDA receptor antagonists induce recovery of synapses lost following exposure to HIV-1 Tat

(2011) AH Shin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neuronal Nitric Oxide Contributes to Neuroplasticity-Associated Protein Expression through cGMP, Protein Kinase G, and Extracellular Signal-Regulated Kinase

(2011) E. F. Gallo et al.   JOURNAL OF NEUROSCIENCE

Functional Adaptation of the N-Methyl-D-aspartate Receptor to Inhibition by Ethanol Is Modulated by Striatal-Enriched Protein Tyrosine Phosphatase and p38 Mitogen-Activated Protein Kinase

(2011) P. H. Wu et al.   MOLECULAR PHARMACOLOGY

Activation of Cannabinoid Type 2 Receptors Inhibits HIV-1 Envelope Glycoprotein gp120-Induced Synapse Loss

(2011) H. J. Kim et al.   MOLECULAR PHARMACOLOGY

Mechanisms of HIV-tat-Induced Phosphorylation of N-Methyl-d-Aspartate Receptor Subunit 2A in Human Primary Neurons

(2010) Jessie E. King et al.   AMERICAN JOURNAL OF PATHOLOGY

Nitric Oxide Induces Pathological Synapse Loss by a Protein Kinase G-, Rho Kinase-Dependent Mechanism Preceded by Myosin Light Chain Phosphorylation

(2010) C. R. Sunico et al.   JOURNAL OF NEUROSCIENCE

HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors

(2010) Robert K. Heaton et al.   JOURNAL OF NEUROVIROLOGY

Down-Regulation of Synaptic GluN2B Subunit-Containing N-methyl-D-aspartate Receptors: A Physiological Brake on CA1 Neuron  -Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Hyperexcitability during Benzodiazepine Withdrawal

(2010) G. Shen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

Role of Tat Protein in HIV Neuropathogenesis

(2009) Wenxue Li et al.   NEUROTOXICITY RESEARCH

Ligand Binding to LRP1 Transactivates Trk Receptors by a Src Family Kinase-Dependent Pathway

(2009) Y. Shi et al.   Science Signaling

HIV-1 Tat C-terminus is cleaved by calpain 1: Implication for Tat-mediated neurotoxicity

(2008) Giovanni Passiatore et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Human Immunodeficiency Virus Protein Tat Induces Synapse Loss via a Reversible Process That Is Distinct from Cell Death

(2008) H. J. Kim et al.   JOURNAL OF NEUROSCIENCE

NMDA Receptor Activation by HIV-Tat Protein Is Clade Dependent

(2008) W. Li et al.   JOURNAL OF NEUROSCIENCE