HIV-1 Tat activates a RhoA signaling pathway to reduce NMDA-evoked calcium responses in hippocampal neurons via an actin-dependent mechanism

Dynamic plasticity of NMDA receptor-mediated calcium entry in neurons exposed to HIV-tat

(2014) Gabriela K. Popescu   JOURNAL OF NEUROCHEMISTRY

HIV-1 protein Tat produces biphasic changes in NMDA-evoked increases in intracellular Ca2+concentration via activation of Src kinase and nitric oxide signaling pathways

(2014) Kelly A. Krogh et al.   JOURNAL OF NEUROCHEMISTRY

Erratum: Corrigendum: Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer’s disease model

(2014) Zheng Wu et al.   Nature Communications

Fasudil, a rho kinase inhibitor, limits motor neuron loss in experimental models of amyotrophic lateral sclerosis

(2013) M Takata et al.   BRITISH JOURNAL OF PHARMACOLOGY

Rho Kinase Inhibitor Fasudil Protects againstβ-Amyloid-Induced Hippocampal Neurodegeneration in Rats

(2013) Yun Song et al.   CNS Neuroscience & Therapeutics

Synaptodendritic recovery following HIV Tat exposure: Neurorestoration by phytoestrogens

(2013) Sarah J. Bertrand et al.   JOURNAL OF NEUROCHEMISTRY

Human Immunodeficiency Virus-1 Tat Protein Increases the Number of Inhibitory Synapses between Hippocampal Neurons in Culture

(2013) N. J. Hargus et al.   JOURNAL OF NEUROSCIENCE

Detection of anti-tat antibodies in CSF of individuals with HIV-associated neurocognitive disorders

(2013) M. Bachani et al.   JOURNAL OF NEUROVIROLOGY

Opposite Roles of NMDA Receptors in Relapsing and Primary Progressive Multiple Sclerosis

(2013) Silvia Rossi et al.   PLoS One

Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice

(2013) Julio Pozueta et al.   Nature Communications

Role of the N-methyl-d-aspartate receptors complex in amyotrophic lateral sclerosis

(2012) Alida Spalloni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Synaptic Dysfunction in the Hippocampus Accompanies Learning and Memory Deficits in Human Immunodeficiency Virus Type-1 Tat Transgenic Mice

(2012) Sylvia Fitting et al.   BIOLOGICAL PSYCHIATRY

Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease

(2012) L. Tonges et al.   BRAIN

Epileptiform stimulus increases Homer 1a expression to modulate synapse number and activity in hippocampal cultures

(2012) Yan Li et al.   JOURNAL OF NEUROPHYSIOLOGY

HIV-1 Tat Triggers Nuclear Localization of ZO-1 via Rho Signaling and cAMP Response Element-Binding Protein Activation

(2012) Y. Zhong et al.   JOURNAL OF NEUROSCIENCE

Human immunodeficiency virus-1 protein Tat induces excitotoxic loss of presynaptic terminals in hippocampal cultures

(2012) Angela H. Shin et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Epileptic stimulus increases Homer 1a expression to modulate endocannabinoid signaling in cultured hippocampal neurons

(2012) Yan Li et al.   NEUROPHARMACOLOGY

Expression of HIV-Tat protein is associated with learning and memory deficits in the mouse

(2011) Amanda N. Carey et al.   BEHAVIOURAL BRAIN RESEARCH

HIV-1 Tat protein increases the permeability of brain endothelial cells by both inhibiting occludin expression and cleaving occludin via matrix metalloproteinase-9

(2011) Ruifen Xu et al.   BRAIN RESEARCH

Subtype selective NMDA receptor antagonists induce recovery of synapses lost following exposure to HIV-1 Tat

(2011) AH Shin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of Cannabinoid Type 2 Receptors Inhibits HIV-1 Envelope Glycoprotein gp120-Induced Synapse Loss

(2011) H. J. Kim et al.   MOLECULAR PHARMACOLOGY

Interactive Comorbidity between Opioid Drug Abuse and HIV-1 Tat

(2010) Sylvia Fitting et al.   AMERICAN JOURNAL OF PATHOLOGY

Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity

(2010) Mutsuki Amano et al.   Cytoskeleton

Nitric Oxide Induces Pathological Synapse Loss by a Protein Kinase G-, Rho Kinase-Dependent Mechanism Preceded by Myosin Light Chain Phosphorylation

(2010) C. R. Sunico et al.   JOURNAL OF NEUROSCIENCE

HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors

(2010) Robert K. Heaton et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

Homeostatic regulation of glutamatergic transmission by dopamine D4 receptors

(2010) E. Y. Yuen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peripheral delivery of a ROCK inhibitor improves learning and working memory.

(2009) Matthew J. Huentelman et al.   BEHAVIORAL NEUROSCIENCE

Intact Lipid Rafts Regulate HIV-1 Tat Protein-Induced Activation of the Rho Signaling and Upregulation of P-Glycoprotein in Brain Endothelial Cells

(2009) Yu Zhong et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Role of Tat Protein in HIV Neuropathogenesis

(2009) Wenxue Li et al.   NEUROTOXICITY RESEARCH

Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease

(2008) David Sulzer et al.   JOURNAL OF NEUROCHEMISTRY

Human Immunodeficiency Virus Protein Tat Induces Synapse Loss via a Reversible Process That Is Distinct from Cell Death

(2008) H. J. Kim et al.   JOURNAL OF NEUROSCIENCE

Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy

(2008) Lorenzo A. Cingolani et al.   NATURE REVIEWS NEUROSCIENCE

Abelson tyrosine kinase links PDGFbeta receptor activation to cytoskeletal regulation of NMDA receptors in CA1 hippocampal neurons

(2008) Michael A Beazely et al.   Molecular Brain