When too much ATP is a bad thing: a pivotal role for P2X7receptors in motor neuron degeneration

Silencing of the P2X7 receptor enhances amyloid-β phagocytosis by microglia

(2013) Jiong Ni et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

P2X7 receptor-induced death of motor neurons by a peroxynitrite/FAS-dependent pathway

(2013) Mandi Gandelman et al.   JOURNAL OF NEUROCHEMISTRY

The P2X7 receptor as a route for non-exocytotic glutamate release: dependence on the carboxyl tail

(2013) Chiara Cervetto et al.   JOURNAL OF NEUROCHEMISTRY

Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis

(2013) Shin H Kang et al.   NATURE NEUROSCIENCE

P2X7 Receptors: Channels, Pores and More

(2012) C. Volonte et al.   CNS & Neurological Disorders-Drug Targets

P2 Receptors for Extracellular Nucleotides in the Central Nervous System: Role of P2X7 and P2Y2 Receptor Interactions in Neuroinflammation

(2012) Gary A. Weisman et al.   MOLECULAR NEUROBIOLOGY

In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases

(2011) Juan Ignacio Diaz-Hernandez et al.   NEUROBIOLOGY OF AGING

Extracellular ATP and the P2X7 receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis

(2010) Mandi Gandelman et al.   Journal of Neuroinflammation

Astrogliosis in amyotrophic lateral sclerosis: Role and therapeutic potential of astrocytes

(2010) Marcelo R. Vargas et al.   Neurotherapeutics

Altered P2X7-receptor level and function in mouse models of Huntington’s disease and therapeutic efficacy of antagonist administration

(2009) Miguel Díaz-Hernández et al.   FASEB JOURNAL