‘Clinical trials in Alzheimer’s disease’: immunotherapy approaches

Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup

(2011) Reisa A. Sperling et al.   Alzheimers & Dementia

Managing Cognitive Dysfunction through the Continuum of Alzheimerʼs Disease

(2011) Julien Delrieu et al.   CNS DRUGS

Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain

(2011) Allal Boutajangout et al.   JOURNAL OF NEUROCHEMISTRY

Safety and Changes in Plasma and Cerebrospinal Fluid Amyloid β After a Single Administration of an Amyloid β Monoclonal Antibody in Subjects With Alzheimer Disease

(2010) Eric R. Siemers et al.   CLINICAL NEUROPHARMACOLOGY

Intravenous Immunoglobulins as a Treatment for Alzheimerʼs Disease

(2010) Richard Dodel et al.   DRUGS

Human intravenous immunoglobulin provides protection against Aβ toxicity by multiple mechanisms in a mouse model of Alzheimer's disease

(2010) Johanna Magga et al.   Journal of Neuroinflammation

11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study

(2010) Juha O Rinne et al.   LANCET NEUROLOGY

Biomarkers in Alzheimer's Disease

(2009) N Coley et al.   Annals of the New York Academy of Sciences

Immunotherapy, Vascular Pathology, and Microhemorrhages in Transgenic Mice

(2009) Donna Wilcock et al.   CNS & Neurological Disorders-Drug Targets

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY

A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease

(2009) S. Salloway et al.   NEUROLOGY

Consequence of Aβ immunization on the vasculature of human Alzheimer's disease brain

(2008) D. Boche et al.   BRAIN

Immunotherapy Reduces Vascular Amyloid-  in PDAPP Mice

(2008) S. Schroeter et al.   JOURNAL OF NEUROSCIENCE

Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

(2008) Clive Holmes et al.   LANCET