Complex molecular regulation of tyrosine hydroxylase

Caveat Emptor: Single Nucleotide Polymorphism Reporting in Pharmacogenomics

(2014) Izel Tekin et al.   PHARMACOLOGY

A new model for allosteric regulation of phenylalanine hydroxylase: Implications for disease and therapeutics

(2013) Eileen K. Jaffe et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Mechanisms of tryptophan and tyrosine hydroxylase

(2013) Kenneth M. Roberts et al.   IUBMB LIFE

The N-Terminal Sequence of Tyrosine Hydroxylase Is a Conformationally Versatile Motif That Binds 14-3-3 Proteins and Membranes

(2013) Åge Aleksander Skjevik et al.   JOURNAL OF MOLECULAR BIOLOGY

The Solution Structure of the Regulatory Domain of Tyrosine Hydroxylase

(2013) Shengnan Zhang et al.   JOURNAL OF MOLECULAR BIOLOGY

Foxa1 and Foxa2 Are Required for the Maintenance of Dopaminergic Properties in Ventral Midbrain Neurons at Late Embryonic Stages

(2013) S. R. W. Stott et al.   JOURNAL OF NEUROSCIENCE

Tyrosine Hydroxylase Gene: Another Piece of the Genetic Puzzle of Parkinson’s Disease

(2012) Guney Bademci et al.   CNS & Neurological Disorders-Drug Targets

Overview of Tyrosine Hydroxylase in Parkinson’s Disease

(2012) Yanzhen Zhu et al.   CNS & Neurological Disorders-Drug Targets

ERK1/2 MAP kinases: Structure, function, and regulation

(2012) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Phosphorylation of the N-terminal portion of tyrosine hydroxylase triggers proteasomal digestion of the enzyme

(2011) Akira Nakashima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mutational Analysis of Catecholamine Binding in Tyrosine Hydroxylase

(2011) Gabrielle D. Briggs et al.   BIOCHEMISTRY

Fluorescence Spectroscopy as a Probe of the Effect of Phosphorylation at Serine 40 of Tyrosine Hydroxylase on the Conformation of Its Regulatory Domain

(2011) Shanzhi Wang et al.   BIOCHEMISTRY

The co-transduction of Nurr1 and Brn4 genes induces the differentiation of neural stem cells into dopaminergic neurons

(2011) Xue‑Feng Tan et al.   CELL BIOLOGY INTERNATIONAL

Epigenetic, transcriptional and posttranscriptional regulation of the tyrosine hydroxylase gene

(2011) Robert Lenartowski et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

gp130 cytokines stimulate proteasomal degradation of tyrosine hydroxylase via extracellular signal regulated kinases 1 and 2

(2011) Xiao Shi et al.   JOURNAL OF NEUROCHEMISTRY

Differential and Interactive Effects of Ligand-Bound Progesterone Receptor A and B Isoforms on Tyrosine Hydroxylase Promoter Activity

(2011) P. J. Jensik et al.   JOURNAL OF NEUROENDOCRINOLOGY

Progesterone receptor isoforms differentially regulate the expression of tryptophan and tyrosine hydroxylase and glutamic acid decarboxylase in the rat hypothalamus

(2011) Oscar González-Flores et al.   NEUROCHEMISTRY INTERNATIONAL

Intracerebroventricular administration of ouabain, a Na/K-ATPase inhibitor, activates tyrosine hydroxylase through extracellular signal-regulated kinase in rat striatum

(2011) Hyun Sook Yu et al.   NEUROCHEMISTRY INTERNATIONAL

Protein Kinase C-Dependent Dephosphorylation of Tyrosine Hydroxylase Requires the B56δ Heterotrimeric Form of Protein Phosphatase 2A

(2011) Jung-Hyuck Ahn et al.   PLoS One

Tyrosine hydroxylase and regulation of dopamine synthesis

(2010) S. Colette Daubner et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Tyrosine hydroxylase deficiency: a treatable disorder of brain catecholamine biosynthesis

(2010) M. A. Willemsen et al.   BRAIN

Hereditary progressive dystonia with marked diurnal fluctuation

(2010) Masaya Segawa   BRAIN & DEVELOPMENT

Serine 129 Phosphorylation Reduces the Ability of α-Synuclein to Regulate Tyrosine Hydroxylase and Protein Phosphatase 2Ain Vitroandin Vivo

(2010) Haiyan Lou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Advanced Research on Dopamine Signaling to Develop Drugs for the Treatment of Mental Disorders: Regulation of Dopaminergic Neural Transmission by Tyrosine Hydroxylase Protein at Nerve Terminals

(2010) Chiho Sumi-Ichinose et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Deletion mutants of tyrosine hydroxylase identify a region critical for heparin binding

(2010) S. Colette Daubner et al.   PROTEIN SCIENCE

Post-transcriptional Regulation of Tyrosine Hydroxylase Expression in Adrenal Medulla and Brain

(2009) A. William Tank et al.   Annals of the New York Academy of Sciences

Pattern-Specific Sustained Activation of Tyrosine Hydroxylase by Intermittent Hypoxia: Role of Reactive Oxygen Species-Dependent Downregulation of Protein Phosphatase 2A and Upregulation of Protein Kinases

(2009) Gayatri Raghuraman et al.   ANTIOXIDANTS & REDOX SIGNALING

Development of neurotransmitter phenotypes in sympathetic neurons

(2009) Galina Apostolova et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Molecular Determinants for PP2A Substrate Specificity: Charged Residues Mediate Dephosphorylation of Tyrosine Hydroxylase by the PP2A/B′ Regulatory Subunit

(2009) Amit Saraf et al.   BIOCHEMISTRY

Differential regulation of human tyrosine hydroxylase isoforms 1 and 2 in situ: Isoform 2 is not phosphorylated at Ser35

(2009) Sarah L. Gordon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression

(2009) F. M. J. Jacobs et al.   DEVELOPMENT

Three-way Interaction between 14-3-3 Proteins, the N-terminal Region of Tyrosine Hydroxylase, and Negatively Charged Membranes

(2009) Øyvind Halskau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

14-3-3ζ Contributes to Tyrosine Hydroxylase Activity in MN9D Cells

(2009) Jian Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Biochemical and Functional Protein Complex Involving Dopamine Synthesis and Transport into Synaptic Vesicles

(2009) Etienne A. Cartier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of N-terminus of tyrosine hydroxylase in the biosynthesis of catecholamines

(2009) A. Nakashima et al.   JOURNAL OF NEURAL TRANSMISSION

Accumulation of phosphorylated tyrosine hydroxylase into insoluble protein aggregates by inhibition of an ubiquitin–proteasome system in PC12D cells

(2009) Ichiro Kawahata et al.   JOURNAL OF NEURAL TRANSMISSION

Angiotensin-(1-7) through AT2receptors mediates tyrosine hydroxylase degradation via the ubiquitin-proteasome pathway

(2009) María A. Lopez Verrilli et al.   JOURNAL OF NEUROCHEMISTRY

Membrane-initiated estradiol signaling increases tyrosine hydroxylase promoter activity with ERα in PC12 cells

(2009) Shreekrishna Maharjan et al.   JOURNAL OF NEUROCHEMISTRY

Spectroscopy and Kinetics of Wild-Type and Mutant Tyrosine Hydroxylase: Mechanistic Insight into O2Activation

(2009) Marina S. Chow et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

cAMP-Mediated Stimulation of Tyrosine Hydroxylase mRNA Translation Is Mediated by Polypyrimidine-Rich Sequences within Its 3'-Untranslated Region and Poly(C)-Binding Protein 2

(2009) L. Xu et al.   MOLECULAR PHARMACOLOGY

The Low Affinity Dopamine Binding Site on Tyrosine Hydroxylase: The Role of the N-Terminus and In Situ Regulation of Enzyme Activity

(2009) Sarah L. Gordon et al.   NEUROCHEMICAL RESEARCH

Modulation of α-Synuclein Aggregation by Dopamine: A Review

(2009) Su Ling Leong et al.   NEUROCHEMICAL RESEARCH

The 14-3-3 Protein Affects the Conformation of the Regulatory Domain of Human Tyrosine Hydroxylase†

(2008) Veronika Obsilova et al.   BIOCHEMISTRY

Mutations in human monoamine-related neurotransmitter pathway genes

(2008) Jan Haavik et al.   HUMAN MUTATION

Direct Binding of GTP Cyclohydrolase and Tyrosine Hydroxylase

(2008) Kevin M. Bowling et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Tyrosine Hydroxylase mRNA Translation by cAMP in Midbrain Dopaminergic Neurons

(2008) X. Chen et al.   MOLECULAR PHARMACOLOGY

Identification of an Activator Protein-1-Like Sequence as the Glucocorticoid Response Element in the Rat Tyrosine Hydroxylase Gene

(2008) C. S. S. Rani et al.   MOLECULAR PHARMACOLOGY

α-Synuclein aggregation alters tyrosine hydroxylase phosphorylation and immunoreactivity: Lessons from viral transduction of knockout mice

(2008) Tshianda N.M. Alerte et al.   NEUROSCIENCE LETTERS

Tyrosine hydroxylase phosphorylation increases in response to ATP and neuropeptide Y co-stimulation of ERK2 phosphorylation

(2008) T LUKE et al.   PHARMACOLOGICAL RESEARCH

Phosphorylation State of Tyrosine Hydroxylase in the Stalk-Median Eminence Is Decreased by Progesterone in Cycling Female Rats

(2007) Bin Liu et al.   ENDOCRINOLOGY

A Nurr1 point mutant, implicated in Parkinson’s disease, uncouples ERK1/2-dependent regulation of tyrosine hydroxylase transcription

(2007) Kirsten X. Jacobsen et al.   NEUROBIOLOGY OF DISEASE

Dopamine Inhibition of Human Tyrosine Hydroxylase Type 1 Is Controlled by the Specific Portion in the N-Terminus of the Enzyme

(2003) Akira Nakashima et al.   JOURNAL OF NEUROCHEMISTRY

A Response Element for the Homeodomain Transcription Factor Ptx3 in the Tyrosine Hydroxylase Gene Promoter

(2003) Pilar Cazorla et al.   JOURNAL OF NEUROCHEMISTRY

Depolarization-stimulated catecholamine biosynthesis: involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ

(2003) Michael F. Salvatore et al.   JOURNAL OF NEUROCHEMISTRY