gp130 cytokines stimulate proteasomal degradation of tyrosine hydroxylase via extracellular signal regulated kinases 1 and 2

Phosphorylation of the N-terminal portion of tyrosine hydroxylase triggers proteasomal digestion of the enzyme

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Cytokines inhibit norepinephrine transporter expression by decreasing Hand2

(2011) Michael J. Pellegrino et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Sympathetic Activation in Obesity

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Differential effects of insulin on sympathetic nerve activity in agouti obese mice

(2010) Donald A Morgan et al.   JOURNAL OF HYPERTENSION

The Stability of Endogenous Tyrosine Hydroxylase Protein in PC-12 Cells Differs from That Expressed in Mouse Fibroblasts by Gene Transfer

(2010) Doris K. Wu et al.   JOURNAL OF NEUROCHEMISTRY

Systemic Administration of Proteasome Inhibitor Protects Against MPTP Neurotoxicity in Mice

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Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats

(2009) Ahmed A. Elmarakby et al.   CLINICAL SCIENCE

Infarction-induced cytokines cause local depletion of tyrosine hydroxylase in cardiac sympathetic nerves

(2009) Diana C. Parrish et al.   EXPERIMENTAL PHYSIOLOGY

Angiotensin-(1-7) through AT2receptors mediates tyrosine hydroxylase degradation via the ubiquitin-proteasome pathway

(2009) María A. Lopez Verrilli et al.   JOURNAL OF NEUROCHEMISTRY

Roles of STAT3/SOCS3 Pathway in Regulating the Visual Function and Ubiquitin-Proteasome-dependent Degradation of Rhodopsin during Retinal Inflammation

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Postinfarct sympathetic hyperactivity differentially stimulates expression of tyrosine hydroxylase and norepinephrine transporter

(2007) Diana C. Parrish et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Differential expression of cardiac neurotrophic factors and sympathetic nerve ending abnormalities within the failing heart

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