Iron-chelating backbone coupled with monoamine oxidase inhibitory moiety as novel pluripotential therapeutic agents for Alzheimer’s disease: a tribute to Moussa Youdim

Site-Activated Chelators Targeting Acetylcholinesterase and Monoamine Oxidase for Alzheimer’s Therapy

(2010) Hailin Zheng et al.   ACS Chemical Biology

Neuroprotective Multifunctional Iron Chelators: From Redox-Sensitive Process to Novel Therapeutic Opportunities

(2010) Orly Weinreb et al.   ANTIOXIDANTS & REDOX SIGNALING

Up-Regulation of Hypoxia-Inducible Factor (HIF)-1α and HIF-Target Genes in Cortical Neurons by the Novel Multifunctional Iron Chelator Anti-Alzheimer Drug, M30

(2010) Y. Avramovich-Tirosh et al.   Current Alzheimer Research

The Novel Multifunctional, Iron-Chelating Drugs M30 and HLA20 Protect Pancreatic  -Cell Lines from Oxidative Stress Damage

(2010) D. Mechlovich et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Rasagiline: A novel anti-Parkinsonian monoamine oxidase-B inhibitor with neuroprotective activity

(2010) Orly Weinreb et al.   PROGRESS IN NEUROBIOLOGY

Prolyl Hydroxylase Domain Inhibitors: A Route to HIF Activation and Neuroprotection

(2009) Sarah K. Harten et al.   ANTIOXIDANTS & REDOX SIGNALING

Therapeutic Manipulation of the HIF Hydroxylases

(2009) Simon Nagel et al.   ANTIOXIDANTS & REDOX SIGNALING

Biological markers of amyloid β-related mechanisms in Alzheimer's disease

(2009) Harald Hampel et al.   EXPERIMENTAL NEUROLOGY

Neuroprotective and neuritogenic activities of novel multimodal iron-chelating drugs in motor-neuron-like NSC-34 cells and transgenic mouse model of amyotrophic lateral sclerosis

(2009) Lana Kupershmidt et al.   FASEB JOURNAL

Effects of Clioquinol on Metal-Triggered Amyloid-β Aggregation Revisited

(2009) Allana M. Mancino et al.   INORGANIC CHEMISTRY

Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways

(2009) A. Siddiq et al.   JOURNAL OF NEUROSCIENCE

Chelation therapy for neurodegenerative diseases

(2009) Silvia Bolognin et al.   MEDICINAL RESEARCH REVIEWS

The curious case of clioquinol

(2009) Lauren Cahoon   NATURE MEDICINE

Brain iron homeostasis and neurodegenerative disease

(2009) E. E. Benarroch   NEUROLOGY

An Overview of APP Processing Enzymes and Products

(2009) Vivian W. Chow et al.   NEUROMOLECULAR MEDICINE

Brain iron deficiency and excess; cognitive impairment and neurodegenration with involvement of striatum and hippocampus

(2009) Moussa B. H. Youdim   NEUROTOXICITY RESEARCH

Restoration of Nigrostriatal Dopamine Neurons in Post-MPTP Treatment by the Novel Multifunctional Brain-Permeable Iron Chelator-Monoamine Oxidase Inhibitor Drug, M30

(2009) Shunit Gal et al.   NEUROTOXICITY RESEARCH

Alzheimer's disease, metal ions and metal homeostatic therapy

(2009) Paolo Zatta et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease

(2008) Jack T. Rogers et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Iron chelation as a potential therapy for neurodegenerative disease

(2008) Robert C. Hider et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Physiological and pathological aspects of Aβ in iron homeostasis via 5'UTR in the APP mRNA and the therapeutic use of iron-chelators

(2008) Yael Avramovich-Tirosh et al.   BMC NEUROSCIENCE

Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease

(2008) Ying Liu et al.   FEBS LETTERS

Multi-target-Directed Ligands To Combat Neurodegenerative Diseases

(2008) Andrea Cavalli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Brain Protection by Erythropoietin: A Manifold Task

(2008) Tamer Rabie et al.   PHYSIOLOGY

Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds

(2007) Lorna Piazzi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Targeting multiple Alzheimer’s disease etiologies with multimodal neuroprotective and neurorestorative iron chelators

(2007) Tamar Amit et al.   FASEB JOURNAL

Prolyl 4-hydroxylase activity-responsive transcription factors: From hydroxylation to gene expression and neuroprotection

(2007) Ambreena Siddiq   Frontiers in Bioscience-Landmark

Brain iron pathways and their relevance to Parkinson's disease

(2003) D Berg et al.   JOURNAL OF NEUROCHEMISTRY

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

(2003) Craig S. Atwood et al.   JOURNAL OF NEUROCHEMISTRY