Biomarker candidates of neurodegeneration in Parkinson’s disease for the evaluation of disease-modifying therapeutics

Possible Involvement of Complement Factor C1q in the Clearance of Extracellular Neuromelanin From the Substantia Nigra in Parkinson Disease

(2011) Candan Depboylu et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study

(2011) Brit Mollenhauer et al.   LANCET NEUROLOGY

The deterioration of cardiovascular reflexes in Parkinson's disease

(2010) A. Mesec et al.   ACTA NEUROLOGICA SCANDINAVICA

Cerebrospinal fluid biomarkers for Parkinson disease diagnosis and progression

(2010) Min Shi et al.   ANNALS OF NEUROLOGY

Chaperone-Mediated Autophagy Markers in Parkinson Disease Brains

(2010) Lydia Alvarez-Erviti et al.   ARCHIVES OF NEUROLOGY

Problems associated with fluid biomarkers for Parkinson’s disease

(2010) Jakob Nyhlén et al.   Biomarkers in Medicine

Magnetic resonance imaging markers of Parkinson’s disease nigrostriatal signature

(2010) Patrice Péran et al.   BRAIN

DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease

(2010) Zhen Hong et al.   BRAIN

Biomarkers in Parkinson’s Disease

(2010) John C. Morgan et al.   Current Neurology and Neuroscience Reports

Is the word ‘biomarker’ being properly used by proteomics research in neuroscience?

(2010) Daniel Martins-de-Souza   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Pilot study: peripheral biomarkers for diagnosing sporadic Parkinson’s disease

(2010) Edna Grünblatt et al.   JOURNAL OF NEURAL TRANSMISSION

Increased serum insulin-like growth factor 1 in early idiopathic Parkinson's disease

(2010) J. Godau et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Psychometric attributes of the rating scale for gait evaluation in Parkinson's disease

(2010) Marcos Serrano-Dueñas et al.   MOVEMENT DISORDERS

Reduced but not oxidized cerebrospinal fluid glutathione levels are lowered in Lewy body diseases

(2010) Walter Maetzler et al.   MOVEMENT DISORDERS

Clinical trials of disease-modifying therapies for neurodegenerative diseases: the challenges and the future

(2010) Anthony E Lang   NATURE MEDICINE

Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives

(2010) Harald Hampel et al.   NATURE REVIEWS DRUG DISCOVERY

Selective cell death in neurodegeneration: Why are some neurons spared in vulnerable regions?

(2010) K.L. Double et al.   PROGRESS IN NEUROBIOLOGY

Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene

(2009) Matthias Elstner et al.   ANNALS OF NEUROLOGY

Anticipatory postural adjustments prior to step initiation are hypometric in untreated Parkinson’s disease: an accelerometer-based approach

(2009) M. Mancini et al.   EUROPEAN JOURNAL OF NEUROLOGY

Anti-melanin antibodies are increased in sera in Parkinson's disease

(2009) K.L. Double et al.   EXPERIMENTAL NEUROLOGY

DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders

(2009) Philipp J. Kahle et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pathogenesis of familial Parkinson’s disease: new insights based on monogenic forms of Parkinson’s disease

(2009) Taku Hatano et al.   JOURNAL OF NEUROCHEMISTRY

The instrumented timed up and go test: potential outcome measure for disease modifying therapies in Parkinson's disease

(2009) C. Zampieri et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Bilateral coordination of gait and Parkinson's disease: the effects of dual tasking

(2009) M Plotnik et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Progression of Parkinson's disease in the clinical phase: potential markers

(2009) Walter Maetzler et al.   LANCET NEUROLOGY

Can an accelerometer enhance the utility of the Timed Up & Go Test when evaluating patients with Parkinson's disease?

(2009) Aner Weiss et al.   MEDICAL ENGINEERING & PHYSICS

Evidence that folic acid deficiency is a major determinant of hyperhomocysteinemia in Parkinson´s disease

(2009) Eliseu Felippe dos Santos et al.   METABOLIC BRAIN DISEASE

Development of a System for Measurement and Analysis of Tremor Using a Three-axis Accelerometer

(2009) N. Mamorita et al.   METHODS OF INFORMATION IN MEDICINE

Hereditary parkinsonism: Parkinson disease look-alikes-An algorithm for clinicians to “PARK” genes and beyond

(2009) Christine Klein et al.   MOVEMENT DISORDERS

Cortical hypometabolism assessed by a metabolic ratio in Parkinson's disease primarily reflects cognitive deterioration-[18F]FDG-PET

(2009) Inga Liepelt et al.   MOVEMENT DISORDERS

Parkinson's disease tremor is diminished with relaxation guided imagery

(2009) Ilana Schlesinger et al.   MOVEMENT DISORDERS

Hyposmia and executive dysfunction as predictors of future Parkinson's disease: A prospective study

(2009) Mirthe M. Ponsen et al.   MOVEMENT DISORDERS

Biological fluid biomarkers in neurodegenerative parkinsonism

(2009) Michael Eller et al.   Nature Reviews Neurology

Cortical PIB binding in Lewy body disease is associated with Alzheimer-like characteristics

(2009) Walter Maetzler et al.   NEUROBIOLOGY OF DISEASE

Molecular basis of Parkinsonʼs disease

(2009) Yan Xiang Yang et al.   NEUROREPORT

Metabolomic Profiling in LRRK2-Related Parkinson's Disease

(2009) Krisztina K. Johansen et al.   PLoS One

Clinical proteomics in neurodegenerative disorders

(2008) H. Zetterberg et al.   ACTA NEUROLOGICA SCANDINAVICA

CSF Multianalyte Profile Distinguishes Alzheimer and Parkinson Diseases

(2008) Jing Zhang et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Serum Urate as a Predictor of Clinical and Radiographic Progression in Parkinson Disease

(2008) Michael A. Schwarzschild   ARCHIVES OF NEUROLOGY

Peripheral biomarkers of Parkinson’s disease as early reporters of central neurodegeneration

(2008) Mauro Fasano et al.   Biomarkers in Medicine

Metabolomic profiling to develop blood biomarkers for Parkinson's disease

(2008) M. Bogdanov et al.   BRAIN

Cardiac parasympathetic dysfunction concurrent with cardiac sympathetic denervation in Parkinson's disease

(2008) Mamoru Shibata et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Predictors and course of health-related quality of life in Parkinson's disease

(2008) Elin Bjelland Forsaa et al.   MOVEMENT DISORDERS

Comparison of a timed motor test battery to the Unified Parkinson's Disease Rating Scale-III in Parkinson's disease

(2008) Charlotte A. Haaxma et al.   MOVEMENT DISORDERS

Uric acid in Parkinson's disease

(2008) Ilana Schlesinger et al.   MOVEMENT DISORDERS

Head and trunk rotation during walking turns in Parkinson's disease

(2008) Frances Huxham et al.   MOVEMENT DISORDERS

Correlation between DJ-1 levels in the cerebrospinal fluid and the progression of disabilities in multiple sclerosis patients

(2008) M Hirotani et al.   Multiple Sclerosis Journal

Early Detection of Parkinson’s Disease: Unmet Needs

(2008) Manfred Gerlach et al.   Neurodegenerative Diseases

Review: Familial Parkinson's disease – genetics, clinical phenotype and neuropathology in relation to the common sporadic form of the disease

(2008) Carola Schiesling et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Metabolomics: A Global Biochemical Approach to the Study of Central Nervous System Diseases

(2008) Rima Kaddurah-Daouk et al.   NEUROPSYCHOPHARMACOLOGY

Biomarkers for evaluation of clinical efficacy of multipotential neuroprotective drugs for Alzheimer’s and Parkinson’s diseases

(2008) Ilan Halperin et al.   Neurotherapeutics

Secretion of DJ-1 into the serum of patients with Parkinson's disease

(2007) Chinatsu Maita et al.   NEUROSCIENCE LETTERS