Problems associated with fluid biomarkers for Parkinson’s disease

The Role of Phosphorylation in Synucleinopathies: Focus on Parkinsons Disease

(2012) Nadia Cavallarin et al.   CNS & Neurological Disorders-Drug Targets

Short communication Interleukin-6 levels in cerebrospinal fluid inversely correlate to severity of Parkinson's disease

(2010) T. Müller et al.   ACTA NEUROLOGICA SCANDINAVICA

DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease

(2010) Zhen Hong et al.   BRAIN

Inter-laboratory variation in cerebrospinal fluid biomarkers for Alzheimer's disease: united we stand, divided we fall

(2010) Niklas Mattsson et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

High-molecular-weight β-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients

(2010) Hiroaki Fukumoto et al.   FASEB JOURNAL

Intrinsic disorder in proteins associated with neurodegenerative diseases

(2010) Vladimir et al.   Frontiers in Bioscience-Landmark

CSF synuclein: adding to the biomarker footprint of dementia with Lewy bodies

(2010) B. Mollenhauer et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Differential levels of  -synuclein,  -amyloid42 and tau in CSF between patients with dementia with Lewy bodies and Alzheimer's disease

(2010) K. Kasuga et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Synergistic Interactions between A , Tau, and  -Synuclein: Acceleration of Neuropathology and Cognitive Decline

(2010) L. K. Clinton et al.   JOURNAL OF NEUROSCIENCE

Distinct cerebrospinal fluid amyloid β peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease

(2010) Erik Portelius et al.   Molecular Neurodegeneration

Sleep disturbances in Parkinson's disease

(2010) Matthew Menza et al.   MOVEMENT DISORDERS

Proteomic profiling of cerebrospinal fluid in parkinsonian disorders

(2010) Radu Constantinescu et al.   PARKINSONISM & RELATED DISORDERS

The progression of pathology in Parkinson's disease

(2009) Glenda Margaret Halliday et al.   Annals of the New York Academy of Sciences

Urate as a Predictor of the Rate of Clinical Decline in Parkinson Disease

(2009) Alberto Ascherio   ARCHIVES OF NEUROLOGY

Alzheimer’s disease and CSF biomarkers: key challenges for broad clinical applications

(2009) Niklas Mattsson et al.   Biomarkers in Medicine

Detection of elevated levels of soluble  -synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies

(2009) K. E. Paleologou et al.   BRAIN

Total and phosphorylated tau protein as biological markers of Alzheimer’s disease

(2009) Harald Hampel et al.   EXPERIMENTAL GERONTOLOGY

DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders

(2009) Philipp J. Kahle et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hereditary parkinsonism: Parkinson disease look-alikes-An algorithm for clinicians to “PARK” genes and beyond

(2009) Christine Klein et al.   MOVEMENT DISORDERS

Metabolomics tools for identifying biomarkers for neuropsychiatric diseases

(2009) Marlon P. Quinones et al.   NEUROBIOLOGY OF DISEASE

A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking

(2009) C. E. Teunissen et al.   NEUROLOGY

Serum levels of interleukin-6 are elevated in patients with Parkinson's disease and correlate with physical performance

(2009) Paula Scalzo et al.   NEUROSCIENCE LETTERS

Consecutive analyses of cerebrospinal fluid axonal and glial markers in Parkinson's disease and atypical parkinsonian disorders

(2009) Radu Constantinescu et al.   PARKINSONISM & RELATED DISORDERS

Metabolomic Profiling in LRRK2-Related Parkinson's Disease

(2009) Krisztina K. Johansen et al.   PLoS One

Clinical proteomics in neurodegenerative disorders

(2008) H. Zetterberg et al.   ACTA NEUROLOGICA SCANDINAVICA

Different Patterns of Oxidized Lipid Products in Plasma and Urine of Dengue Fever, Stroke, and Parkinson's Disease Patients: Cautions in the Use of Biomarkers of Oxidative Stress

(2008) Chung-Yung J. Lee et al.   ANTIOXIDANTS & REDOX SIGNALING

Metabolomic profiling to develop blood biomarkers for Parkinson's disease

(2008) M. Bogdanov et al.   BRAIN

Peripheral cytokines profile in Parkinson’s disease

(2008) M. Reale et al.   BRAIN BEHAVIOR AND IMMUNITY

CSF α-synuclein levels in dementia with Lewy bodies and Alzheimer's disease

(2008) Moeko Noguchi-Shinohara et al.   BRAIN RESEARCH

F2 Isoprostane Levels in Plasma and Urine do not Support Increased Lipid Peroxidation in Cognitively Impaired Parkinson Disease Patients

(2008) James Connolly et al.   Cognitive and Behavioral Neurology

Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

(2008) Brit Mollenhauer et al.   EXPERIMENTAL NEUROLOGY

Uric acid in Parkinson's disease

(2008) Ilana Schlesinger et al.   MOVEMENT DISORDERS

Correlation between DJ-1 levels in the cerebrospinal fluid and the progression of disabilities in multiple sclerosis patients

(2008) M Hirotani et al.   Multiple Sclerosis Journal

Lymphomonocyte alpha-synuclein levels in aging and in Parkinson disease

(2008) Laura Brighina et al.   NEUROBIOLOGY OF AGING

Metabolomics: A Global Biochemical Approach to the Study of Central Nervous System Diseases

(2008) Rima Kaddurah-Daouk et al.   NEUROPSYCHOPHARMACOLOGY

Serum interleukin (IL-2, IL-10, IL-6, IL-4), TNFα, and INFγ concentrations are elevated in patients with atypical and idiopathic parkinsonism

(2008) Bogdan Brodacki et al.   NEUROSCIENCE LETTERS

Cerebrospinal fluid α-synuclein in neurodegenerative disorders—A marker of synapse loss?

(2008) Annika Öhrfelt et al.   NEUROSCIENCE LETTERS

Oxidative insults induce DJ-1 upregulation and redistribution: Implications for neuroprotection

(2008) Nirit Lev et al.   NEUROTOXICOLOGY

Uric acid associates with cognition in Parkinson's disease

(2008) Tua Annanmaki et al.   PARKINSONISM & RELATED DISORDERS

Levels of brain related proteins in cerebrospinal fluid: An aid in the differential diagnosis of parkinsonian disorders

(2008) Radu Constantinescu et al.   PARKINSONISM & RELATED DISORDERS

Serum inflammatory biomarkers in Parkinson's disease

(2008) M. Dufek et al.   PARKINSONISM & RELATED DISORDERS

Tissue transglutaminase modulates α-synuclein oligomerization

(2008) Ine M.J. Segers-Nolten et al.   PROTEIN SCIENCE

Proteome analysis of human substantia nigra in Parkinson's disease

(2008) Cornelius J Werner et al.   Proteome Science

Secretion of DJ-1 into the serum of patients with Parkinson's disease

(2007) Chinatsu Maita et al.   NEUROSCIENCE LETTERS