Treatment of Ebola Virus Disease

Clinical Presentation of Patients with Ebola Virus Disease in Conakry, Guinea

(2015) Elhadj Ibrahima Bah et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety and Pharmacokinetic Profiles of Phosphorodiamidate Morpholino Oligomers with Activity against Ebola Virus and Marburg Virus: Results of Two Single-Ascending-Dose Studies

(2014) Alison E. Heald et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model

(2014) Lisa Oestereich et al.   ANTIVIRAL RESEARCH

Post-exposure efficacy of Oral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model

(2014) Sophie J. Smither et al.   ANTIVIRAL RESEARCH

Ebolavirus in West Africa, and the use of experimental therapies or vaccines

(2014) Thomas Hoenen et al.   BMC BIOLOGY

Possible leap ahead in filovirus therapeutics

(2014) Darryl Falzarano et al.   CELL RESEARCH

Development of CMX001 (Brincidofovir) for the treatment of serious diseases or conditions caused by dsDNA viruses

(2014) Diana F Florescu et al.   Expert Review of Anti-Infective Therapy

Reverse genetics systems as tools for the development of novel therapies against filoviruses

(2014) Thomas Hoenen et al.   Expert Review of Anti-Infective Therapy

Tissue and cellular tropism, pathology and pathogenesis of Ebola and Marburg viruses

(2014) Roosecelis Brasil Martines et al.   JOURNAL OF PATHOLOGY

Successful Delivery of RRT in Ebola Virus Disease

(2014) M. J. Connor et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Case fatality rates of Ebola virus diseases: A meta-analysis of World Health Organization data

(2014) A. Lefebvre et al.   MEDECINE ET MALADIES INFECTIEUSES

Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430

(2014) Travis K. Warren et al.   NATURE

Emergence of Zaire Ebola Virus Disease in Guinea

(2014) Sylvain Baize et al.   NEW ENGLAND JOURNAL OF MEDICINE

Studying “Secret Serums” — Toward Safe, Effective Ebola Treatments

(2014) Jesse L. Goodman   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Illness and Outcomes in Patients with Ebola in Sierra Leone

(2014) John S. Schieffelin et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Case of Severe Ebola Virus Infection Complicated by Gram-Negative Septicemia

(2014) Benno Kreuels et al.   NEW ENGLAND JOURNAL OF MEDICINE

What Obstetrician–Gynecologists Should Know About Ebola

(2014) Denise J. Jamieson et al.   OBSTETRICS AND GYNECOLOGY

Basic Science and the Ebola Virus Infection Epidemic

(2014) C. Lindsay DeVane   PHARMACOTHERAPY

Structures of protective antibodies reveal sites of vulnerability on Ebola virus

(2014) Charles D. Murin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fighting Ebola with ZMapp: spotlight on plant-made antibody

(2014) YunFang Zhang et al.   Science China-Life Sciences

Post-exposure therapy of filovirus infections

(2014) Gary Wong et al.   TRENDS IN MICROBIOLOGY

Favipiravir elicits antiviral mutagenesis during virus replication in vivo

(2014) Armando Arias et al.   eLife

Emerging Targets and Novel Approaches to Ebola Virus Prophylaxis and Treatment

(2013) Jin Huk Choi et al.   BIODRUGS

Therapeutic Intervention of Ebola Virus Infection in Rhesus Macaques with the MB-003 Monoclonal Antibody Cocktail

(2013) J. Pettitt et al.   Science Translational Medicine

Pathogenesis of the Viral Hemorrhagic Fevers

(2012) Slobodan Paessler et al.   Annual Review of Pathology-Mechanisms of Disease

Characterization of the RNA Silencing Suppression Activity of the Ebola Virus VP35 Protein in Plants and Mammalian Cells

(2012) Y. Zhu et al.   JOURNAL OF VIROLOGY

Delayed treatment of Ebola virus infection with plant-derived monoclonal antibodies provides protection in rhesus macaques

(2012) G. G. Olinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus Infections

(2012) Patrick Iversen et al.   Viruses-Basel

The ebolavirus VP24 interferon antagonist

(2012) Adrianna P.P. Zhang et al.   Virulence

The Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal Fold

(2012) Adrianna P. P. Zhang et al.   PLoS Pathogens

Role of VP30 Phosphorylation in the Ebola Virus Replication Cycle

(2011) Miguel J. Martinez et al.   JOURNAL OF INFECTIOUS DISEASES

Ebolavirus Proteins Suppress the Effects of Small Interfering RNA by Direct Interaction with the Mammalian RNA Interference Pathway

(2011) G. Fabozzi et al.   JOURNAL OF VIROLOGY

Inactivated or Live-Attenuated Bivalent Vaccines That Confer Protection against Rabies and Ebola Viruses

(2011) J. E. Blaney et al.   JOURNAL OF VIROLOGY

Aerosol exposure to Zaire ebolavirus in three nonhuman primate species: differences in disease course and clinical pathology

(2011) Douglas S. Reed et al.   MICROBES AND INFECTION

Microbial Induction of Vascular Pathology in the CNS

(2010) Silvia S. Kang et al.   Journal of Neuroimmune Pharmacology

Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study

(2010) Thomas W Geisbert et al.   LANCET

Ebola haemorrhagic fever

(2010) Heinz Feldmann et al.   LANCET

Treatment of Marburg and Ebola hemorrhagic fevers: A strategy for testing new drugs and vaccines under outbreak conditions

(2008) Daniel G. Bausch et al.   ANTIVIRAL RESEARCH

Treatment of Argentine hemorrhagic fever

(2007) Delia A. Enria et al.   ANTIVIRAL RESEARCH