Non-viral gene delivery strategies for gene therapy: a “ménage à trois” among nucleic acids, materials, and the biological environment
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Title
Non-viral gene delivery strategies for gene therapy: a “ménage à trois” among nucleic acids, materials, and the biological environment
Authors
Keywords
Non-viral gene delivery, Cationic polymer, Cationic lipid, Stimuli-responsive, Transfection, Hydrolyzable, Redox-sensitive, pH-sensitive
Journal
JOURNAL OF NANOPARTICLE RESEARCH
Volume 15, Issue 3, Pages -
Publisher
Springer Nature
Online
2013-02-23
DOI
10.1007/s11051-013-1523-7
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- (2012) M. P. Limberis ACTA BIOCHIMICA ET BIOPHYSICA SINICA
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- (2012) Lara Lacerda et al. BIOMATERIALS
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- (2012) Connie Cheng et al. BIOMATERIALS
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- (2012) Javier Guerra et al. CARBON
- AAVs Anatomy: Roadmap for Optimizing Vectors for Translational Success
- (2012) Angela M. Mitchell et al. CURRENT GENE THERAPY
- Directed evolution of novel adeno-associated viruses for therapeutic gene delivery
- (2012) M A Bartel et al. GENE THERAPY
- Genetic blockage of endocytic pathways reveals differences in the intracellular processing of non-viral gene delivery systems
- (2012) Polina Ilina et al. JOURNAL OF CONTROLLED RELEASE
- The yin of exofacial protein sulfhydryls and the yang of intracellular glutathione in in vitro transfection with SS14 bioreducible lipoplexes
- (2012) Daniele Pezzoli et al. JOURNAL OF CONTROLLED RELEASE
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- (2012) Aditya Kulkarni et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Type I IFN Counteracts the Induction of Antigen-Specific Immune Responses by Lipid-Based Delivery of mRNA Vaccines
- (2012) Charlotte Pollard et al. MOLECULAR THERAPY
- Bioreducible Crosslinked Polyelectrolyte Complexes for MMP-2 siRNA Delivery into Human Vascular Smooth Muscle Cells
- (2012) Dokyoung Lee et al. PHARMACEUTICAL RESEARCH
- Chitosan-Graft-Branched Polyethylenimine Copolymers: Influence of Degree of Grafting on Transfection Behavior
- (2012) Daniele Pezzoli et al. PLoS One
- Before and after Endosomal Escape: Roles of Stimuli-Converting siRNA/Polymer Interactions in Determining Gene Silencing Efficiency
- (2011) Young Jik Kwon ACCOUNTS OF CHEMICAL RESEARCH
- Recent Advances in Nonviral Vectors for Gene Delivery
- (2011) Xia Guo et al. ACCOUNTS OF CHEMICAL RESEARCH
- Cellular Association and Cargo Release of Redox-Responsive Polymer Capsules Mediated by Exofacial Thiols
- (2011) Yan Yan et al. ADVANCED MATERIALS
- Control of pH responsive peptide self-association during endocytosis is required for effective gene transfer
- (2011) Valentina Iacobucci et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Synthesis, Characterization, andIn VitroTransfection Activity of Charge-Reversal Amphiphiles for DNA Delivery
- (2011) Xiao-Xiang Zhang et al. BIOCONJUGATE CHEMISTRY
- The intracellular plasmid DNA localization of cationic reducible cholesterol-disulfide lipids
- (2011) Ruilong Sheng et al. BIOMATERIALS
- Dual mode polyspermine with tunable degradability for plasmid DNA and siRNA delivery
- (2011) Min Suk Shim et al. BIOMATERIALS
- Non-viral gene delivery nanoparticles based on Poly(β-amino esters) for treatment of glioblastoma
- (2011) Stephany Y. Tzeng et al. BIOMATERIALS
- A brain-targeted rabies virus glycoprotein-disulfide linked PEI nanocarrier for delivery of neurogenic microRNA
- (2011) Do Won Hwang et al. BIOMATERIALS
- Self-assembled carboxymethyl poly (l-histidine) coated poly (β-amino ester)/DNA complexes for gene transfection
- (2011) Jijin Gu et al. BIOMATERIALS
- Diblock copolymers with tunable pH transitions for gene delivery
- (2011) Matthew J. Manganiello et al. BIOMATERIALS
- Biomedical application of plasmid DNA in gene therapy: A new challenge for chromatography
- (2011) F. Sousa et al. Biotechnology & Genetic Engineering Reviews
- MicroRNA Replacement Therapy for miR-145 and miR-33a Is Efficacious in a Model of Colon Carcinoma
- (2011) A. F. Ibrahim et al. CANCER RESEARCH
- Tumor vaccination using messenger RNA: prospects of a future therapy
- (2011) Sebastian Kreiter et al. CURRENT OPINION IN IMMUNOLOGY
- Bioreducible poly (β-amino esters)/shRNA complex nanoparticles for efficient RNA delivery
- (2011) Qi Yin et al. JOURNAL OF CONTROLLED RELEASE
- Rational design of biodegradable cationic polycarbonates for gene delivery
- (2011) Zhan Yuin Ong et al. JOURNAL OF CONTROLLED RELEASE
- How to screen non-viral gene delivery systems in vitro?
- (2011) Ethlinn V.B. van Gaal et al. JOURNAL OF CONTROLLED RELEASE
- Glutathione-responsive nano-vehicles as a promising platform for targeted intracellular drug and gene delivery
- (2011) Ru Cheng et al. JOURNAL OF CONTROLLED RELEASE
- Restitution of Tumor Suppressor MicroRNAs Using a Systemic Nanovector Inhibits Pancreatic Cancer Growth in Mice
- (2011) D. Pramanik et al. MOLECULAR CANCER THERAPEUTICS
- Unraveling the Intracellular Efficacy of Dextran-Histidine Polycation as an Efficient Nonviral Gene Delivery System
- (2011) Jane Joy Thomas et al. MOLECULAR PHARMACEUTICS
- In Vitroandin VivomRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles
- (2011) Xingfang Su et al. MOLECULAR PHARMACEUTICS
- The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers
- (2011) Carlee E. Ashley et al. NATURE MATERIALS
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- (2011) Francisco C. Pérez-Martínez et al. PHARMACEUTICAL RESEARCH
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- (2011) Sandra Ristori et al. Soft Matter
- Progress and Outlook of Inorganic Nanoparticles for Delivery of Nucleic Acid Sequences Related to Orthopedic Pathologies: A Review
- (2011) Darcy E. Wagner et al. TISSUE ENGINEERING PART B-REVIEWS
- pDNA-lipoplexes engrafted with flagellin-related peptide induce potent immunity and anti-tumour effects
- (2011) Abdus Faham et al. VACCINE
- Nonviral gene transfer as a tool for studying transcription regulation of xenobiotic metabolizing enzymes
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- (2010) Jin-Oh You et al. BIOMATERIALS
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- (2010) Chunbai He et al. BIOMATERIALS
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- (2010) Aristides D. Tagalakis et al. BIOMATERIALS
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- (2010) Yu Nie et al. BIOMATERIALS
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- (2010) Laura Ciani et al. BIOPHYSICAL CHEMISTRY
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- (2010) Constantinos M Paleos et al. Expert Opinion on Drug Delivery
- Tumor-specific gene transfer with receptor-mediated nanocomplexes modified by polyethylene glycol shielding and endosomally cleavable lipid and peptide linkers
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- DNA vaccines: an historical perspective and view to the future
- (2010) Margaret A. Liu IMMUNOLOGICAL REVIEWS
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- (2010) Viola B. Morris et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
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- (2010) Joanna Rejman et al. JOURNAL OF CONTROLLED RELEASE
- Reducible DNA nanoparticles enhance in vitro gene transfer via an extracellular mechanism
- (2010) Wenchao Sun et al. JOURNAL OF CONTROLLED RELEASE
- mRNA as gene therapeutic: How to control protein expression
- (2010) Geertrui Tavernier et al. JOURNAL OF CONTROLLED RELEASE
- Exofacial Protein Thiols as a Route for the Internalization of Gd(III)-Based Complexes for Magnetic Resonance Imaging Cell Labeling
- (2010) Giuseppe Digilio et al. JOURNAL OF MEDICINAL CHEMISTRY
- Gene Transfer: How Can the Biological Barriers Be Overcome?
- (2010) Jean-Michel Escoffre et al. JOURNAL OF MEMBRANE BIOLOGY
- New Amphiphilic Carriers Forming pH-Sensitive Nanoparticles for Nucleic Acid Delivery
- (2010) Rongzuo Xu et al. LANGMUIR
- Efficient Encapsulation of Plasmid DNA in pH-Sensitive PMPC-PDPA Polymersomes: Study of the Effect of PDPA Block Length on Copolymer-DNA Binding Affinity
- (2010) Hannah Lomas et al. MACROMOLECULAR BIOSCIENCE
- pH-Responsive Polymers as Gene Carriers
- (2010) In-Kyu Park et al. MACROMOLECULAR RAPID COMMUNICATIONS
- Probing the in vitro mechanism of action of cationic lipid/DNA lipoplexes at a nanometric scale
- (2010) Olivier Le Bihan et al. NUCLEIC ACIDS RESEARCH
- Gene Therapy: A Pharmacokinetic/Pharmacodynamic Modelling Overview
- (2010) Zinnia P. Parra-Guillén et al. PHARMACEUTICAL RESEARCH
- Inorganic Nanoparticles in Cancer Therapy
- (2010) Sanjib Bhattacharyya et al. PHARMACEUTICAL RESEARCH
- Bioreducible Liposomes for Gene Delivery: From the Formulation to the Mechanism of Action
- (2010) Gabriele Candiani et al. PLoS One
- RNAi and small interfering RNAs in human disease therapeutic applications
- (2010) Monica R. Lares et al. TRENDS IN BIOTECHNOLOGY
- Chitosan-based formulations for delivery of DNA and siRNA
- (2009) Shirui Mao et al. ADVANCED DRUG DELIVERY REVIEWS
- Delivery of Nucleic Acids via Disulfide-Based Carrier Systems
- (2009) Sonja Bauhuber et al. ADVANCED MATERIALS
- Small-Molecule End-Groups of Linear Polymer Determine Cell-type Gene-Delivery Efficacy
- (2009) Joel Sunshine et al. ADVANCED MATERIALS
- Recent trends in non-viral vector-mediated gene delivery
- (2009) Atul Pathak et al. Biotechnology Journal
- Nuclear drug delivery to target tumour cells
- (2009) Kylie M. Wagstaff et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Viral-based gene delivery and regulated gene expression for targeted cancer therapy
- (2009) Yi Lu et al. Expert Opinion on Drug Delivery
- MicroRNA-23b mediates urokinase and c-met downmodulation and a decreased migration of human hepatocellular carcinoma cells
- (2009) Alessandro Salvi et al. FEBS Journal
- Progress and prospects: immune responses to viral vectors
- (2009) S Nayak et al. GENE THERAPY
- Effect of innate glutathione levels on activity of redox-responsive gene delivery vectors
- (2009) Devika S. Manickam et al. JOURNAL OF CONTROLLED RELEASE
- Flow cytometry for rapid size determination and sorting of nucleic acid containing nanoparticles in biological fluids
- (2009) E.V.B. van Gaal et al. JOURNAL OF CONTROLLED RELEASE
- Novel Cholesterol-Based Cationic Lipids for Gene Delivery
- (2009) Darya A. Medvedeva et al. JOURNAL OF MEDICINAL CHEMISTRY
- Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery
- (2009) C. L. Grigsby et al. Journal of the Royal Society Interface
- REV1 Is Implicated in the Development of Carcinogen-Induced Lung Cancer
- (2009) C. A. Dumstorf et al. MOLECULAR CANCER RESEARCH
- Size Effect on Cell Uptake in Well-Suspended, Uniform Mesoporous Silica Nanoparticles
- (2009) Fang Lu et al. Small
- A Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery
- (2008) Jordan J. Green et al. ACCOUNTS OF CHEMICAL RESEARCH
- Gene-Targeted Therapies for the Central Nervous System
- (2008) Timothy M. Miller et al. ARCHIVES OF NEUROLOGY
- Novel Biodegradable Poly(disulfide amine)s for Gene Delivery with High Efficiency and Low Cytotoxicity
- (2008) Mei Ou et al. BIOCONJUGATE CHEMISTRY
- Controlled Delivery of Plasmid DNA and siRNA to Intracellular Targets Using Ketalized Polyethylenimine
- (2008) Min Suk Shim et al. BIOMACROMOLECULES
- Addition of “Charge-Shifting” Side Chains to Linear Poly(ethyleneimine) Enhances Cell Transfection Efficiency
- (2008) Xianghui Liu et al. BIOMACROMOLECULES
- Acid-degradable cationic methacrylamide polymerized in the presence of plasmid DNA as tunable non-viral gene carrier
- (2008) In Kap Ko et al. BIOMATERIALS
- Nonviral Vectors for Gene Delivery
- (2008) Meredith A. Mintzer et al. CHEMICAL REVIEWS
- Progress and prospects: gene therapy for genetic diseases with helper-dependent adenoviral vectors
- (2008) N Brunetti-Pierri et al. GENE THERAPY
- Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo
- (2008) Miriam Breunig et al. JOURNAL OF CONTROLLED RELEASE
- Tf-lipoplexes for neuronal siRNA delivery: A promising system to mediate gene silencing in the CNS
- (2008) A.L.C. Cardoso et al. JOURNAL OF CONTROLLED RELEASE
- Local and systemic delivery of VEGF siRNA using polyelectrolyte complex micelles for effective treatment of cancer
- (2008) Sun Hwa Kim et al. JOURNAL OF CONTROLLED RELEASE
- A review of stimuli-responsive nanocarriers for drug and gene delivery
- (2008) Srinivas Ganta et al. JOURNAL OF CONTROLLED RELEASE
- Controlled cytoplasmic and nuclear localization of plasmid DNA and siRNA by differentially tailored polyethylenimine
- (2008) Min Suk Shim et al. JOURNAL OF CONTROLLED RELEASE
- A dimerizable cationic lipid with potential for gene delivery
- (2008) Gabriele Candiani et al. JOURNAL OF GENE MEDICINE
- Effect of the Nature of the Spacer on Gene Transfer Efficacies of Novel Thiocholesterol Derived Gemini Lipids in Different Cell Lines: A Structure–Activity Investigation
- (2008) Avinash Bajaj et al. JOURNAL OF MEDICINAL CHEMISTRY
- An Acid Sensitive Ketal-Based Polyethylene Glycol-Oligoethylenimine Copolymer Mediates Improved Transfection Efficiency at Reduced Toxicity
- (2008) Veronika Knorr et al. PHARMACEUTICAL RESEARCH
- Inorganic Nanoparticles as Carriers of Nucleic Acids into Cells
- (2007) Viktoriya Sokolova et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Biodegradable polymers as non-viral carriers for plasmid DNA delivery
- (2007) Jordy Luten et al. JOURNAL OF CONTROLLED RELEASE
- Converging Paths of Viral and Non-viral Vector Engineering
- (2007) Ernst Wagner MOLECULAR THERAPY
- Breaking the Bonds: Non-viral Vectors Become Chemically Dynamic
- (2007) Jon A Wolff et al. MOLECULAR THERAPY
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