Oxidative stress in muscular dystrophy: from generic evidence to specific sources and targets

Mechanical Stretch-Induced Activation of ROS/RNS Signaling in Striated Muscle

(2013) Christopher W. Ward et al.   ANTIOXIDANTS & REDOX SIGNALING

Cysteine Oxidative Posttranslational Modifications

(2013) Heaseung S. Chung et al.   CIRCULATION RESEARCH

Oxidative Stress and Sarcomeric Proteins

(2013) Susan F. Steinberg   CIRCULATION RESEARCH

Oxidative stress and pathology in muscular dystrophies: focus on protein thiol oxidation and dysferlinopathies

(2013) Jessica R. Terrill et al.   FEBS Journal

Visualizing and quantifying oxidized protein thiols in tissue sections: A comparison of dystrophic mdx and normal skeletal mouse muscles

(2013) Tomohito Iwasaki et al.   FREE RADICAL BIOLOGY AND MEDICINE

Wasting mechanisms in muscular dystrophy

(2013) Jonghyun Shin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Redox Biochemistry of Protein Sulfenylation and Sulfinylation

(2013) Mauro Lo Conte et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I

(2013) Edward T Chouchani et al.   NATURE MEDICINE

Dysferlin stabilizes stress-induced Ca2+ signaling in the transverse tubule membrane

(2013) J. P. Kerr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myotonic dystrophy protein kinase (DMPK) prevents ROS-induced cell death by assembling a hexokinase II-Src complex on the mitochondrial surface

(2013) B Pantic et al.   Cell Death & Disease

Lamins as mediators of oxidative stress

(2012) Tom Sieprath et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Redox Signaling in Cardiac Physiology and Pathology

(2012) Joseph R. Burgoyne et al.   CIRCULATION RESEARCH

Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction

(2012) Nicholas K. Tonks   FEBS Journal

Functional muscle impairment in facioscapulohumeral muscular dystrophy is correlated with oxidative stress and mitochondrial dysfunction

(2012) Ahmed Turki et al.   FREE RADICAL BIOLOGY AND MEDICINE

Contribution of oxidative stress to pathology in diaphragm and limb muscles with Duchenne muscular dystrophy

(2012) Jong-Hee Kim et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

S-Glutathionylation of troponin I (fast) increases contractile apparatus Ca2+sensitivity in fast-twitch muscle fibres of rats and humans

(2012) J. P. Mollica et al.   JOURNAL OF PHYSIOLOGY-LONDON

Oxidative Damage in Muscular Dystrophy Correlates with the Severity of the Pathology: Role of Glutathione Metabolism

(2012) R. Renjini et al.   NEUROCHEMICAL RESEARCH

Microtubules Underlie Dysfunction in Duchenne Muscular Dystrophy

(2012) R. J. Khairallah et al.   Science Signaling

Conserved cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation

(2011) Vanja Pekovic et al.   AGING CELL

Basic Principles and Emerging Concepts in the Redox Control of Transcription Factors

(2011) Regina Brigelius-Flohé et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Regulation of Mitochondrial ATP Synthase

(2011) Sheng-Bing Wang et al.   CIRCULATION RESEARCH

Screening for increased protein thiol oxidation in oxidatively stressed muscle tissue

(2011) Ahmed F. El-Shafey et al.   FREE RADICAL RESEARCH

Cysteine 203 of Cyclophilin D Is Critical for Cyclophilin D Activation of the Mitochondrial Permeability Transition Pore

(2011) Tiffany T. Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signal Transduction by Mitochondrial Oxidants

(2011) Toren Finkel   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional regulation and multiple functions of MAO genes

(2011) Jean C. Shih et al.   JOURNAL OF NEURAL TRANSMISSION

Exacerbation of pathology by oxidative stress in respiratory and locomotor muscles with Duchenne muscular dystrophy

(2011) John M. Lawler   JOURNAL OF PHYSIOLOGY-LONDON

Oxidation of Myofibrillar Proteins in Human Heart Failure

(2011) Marcella Canton et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Idebenone as a novel, therapeutic approach for Duchenne muscular dystrophy: Results from a 12 month, double-blind, randomized placebo-controlled trial

(2011) Gunnar M. Buyse et al.   NEUROMUSCULAR DISORDERS

X-ROS Signaling: Rapid Mechano-Chemo Transduction in Heart

(2011) B. L. Prosser et al.   SCIENCE

Mitochondrial Injury and Protection in Ischemic Pre- and Postconditioning

(2010) Fabio Di Lisa et al.   ANTIOXIDANTS & REDOX SIGNALING

The contribution of reactive oxygen species and p38 mitogen-activated protein kinase to myofilament oxidation and progression of heart failure in rabbits

(2010) P Heusch et al.   BRITISH JOURNAL OF PHARMACOLOGY

Oxidative stress by monoamine oxidases is causally involved in myofiber damage in muscular dystrophy

(2010) Sara Menazza et al.   HUMAN MOLECULAR GENETICS

Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy

(2010) Hongqing Du et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Skeletal Muscle NADPH Oxidase Is Increased and Triggers Stretch-Induced Damage in the mdx Mouse

(2010) Nicholas P. Whitehead et al.   PLoS One

A Unifying Genetic Model for Facioscapulohumeral Muscular Dystrophy

(2010) R. J. L. F. Lemmers et al.   SCIENCE

Oxidative stress inSEPN1-related myopathy: From pathophysiology to treatment

(2009) Sandrine Arbogast et al.   ANNALS OF NEUROLOGY

Redox Activity Within the Lysosomal Compartment: Implications for Aging and Apoptosis

(2009) Tino Kurz et al.   ANTIOXIDANTS & REDOX SIGNALING

Protein Carbonylation

(2009) Yuichiro J. Suzuki et al.   ANTIOXIDANTS & REDOX SIGNALING

Selenoproteins and Protection against Oxidative Stress: Selenoprotein N as a Novel Player at the Crossroads of Redox Signaling and Calcium Homeostasis

(2009) Sandrine Arbogast et al.   ANTIOXIDANTS & REDOX SIGNALING

SR/ER–mitochondrial local communication: Calcium and ROS

(2009) György Csordás et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Genetic ablation of cyclophilin D rescues mitochondrial defects and prevents muscle apoptosis in collagen VI myopathic mice

(2009) Elena Palma et al.   HUMAN MOLECULAR GENETICS

Therapeutic targeting of signaling pathways in muscular dystrophy

(2009) Shephali Bhatnagar et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Oxidation of Myofilament Protein Sulfhydryl Groups Reduces the Contractile Force and Its Ca2+ Sensitivity in Human Cardiomyocytes

(2008) Zita Hertelendi et al.   ANTIOXIDANTS & REDOX SIGNALING

Isoprostanes in dystrophinopathy: Evidence of increased oxidative stress

(2008) Salvatore Grosso et al.   BRAIN & DEVELOPMENT

Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance

(2008) G. M. Buyse et al.   EUROPEAN HEART JOURNAL

Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy

(2008) S. A. Villalta et al.   HUMAN MOLECULAR GENETICS

N-Acetylcysteine ameliorates skeletal muscle pathophysiology inmdxmice

(2008) Nicholas P. Whitehead et al.   JOURNAL OF PHYSIOLOGY-LONDON

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy

(2008) Douglas P Millay et al.   NATURE MEDICINE

Dystrophin-deficient cardiomyopathy in mouse: Expression of Nox4 and Lox are associated with fibrosis and altered functional parameters in the heart

(2008) Christopher F. Spurney et al.   NEUROMUSCULAR DISORDERS