Myosin binding protein C: implications for signal-transduction

A Critical Function for Ser-282 in Cardiac Myosin Binding Protein-C Phosphorylation and Cardiac Function

(2011) Sakthivel Sadayappan et al.   CIRCULATION RESEARCH

Towards a re-definition of ‘cardiac hypertrophy’ through a rational characterization of left ventricular phenotypes: a position paper of the Working Group ‘Myocardial Function’ of the ESC

(2011) Ralph Knöll et al.   EUROPEAN JOURNAL OF HEART FAILURE

Structure and Interactions of Myosin-binding Protein C Domain C0

(2011) Joyce Ratti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Sarcomeric Z-Disc and Z-Discopathies

(2011) Ralph Knöll et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Cardiac myosin-binding protein C in hypertrophic cardiomyopathy: Mechanisms and therapeutic opportunities

(2011) Saskia Schlossarek et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Long-term rescue of a familial hypertrophic cardiomyopathy caused by a mutation in the thin filament protein, tropomyosin, via modulation of a calcium cycling protein

(2011) Robert D. Gaffin et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

How Do Mutations in Contractile Proteins Cause the Primary Familial Cardiomyopathies?

(2011) Steven B. Marston   Journal of Cardiovascular Translational Research

Founder mutations in hypertrophic cardiomyopathy patients in the Netherlands

(2011) I. Christiaans* et al.   Netherlands Heart Journal

Metabolic Modulator Perhexiline Corrects Energy Deficiency and Improves Exercise Capacity in Symptomatic Hypertrophic Cardiomyopathy

(2010) Khalid Abozguia et al.   CIRCULATION

Short Communication: The Cardiac Myosin Binding Protein C Arg502Trp Mutation

(2010) Adam J. Saltzman et al.   CIRCULATION RESEARCH

A Common MLP (Muscle LIM Protein) Variant Is Associated With Cardiomyopathy

(2010) Ralph Knöll et al.   CIRCULATION RESEARCH

Atorvastatin and cardiac hypertrophy and function in hypertrophic cardiomyopathy: a pilot study

(2010) Sherif F. Nagueh et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Myosin binding protein C1: a novel gene for autosomal dominant distal arthrogryposis type 1

(2010) Christina A. Gurnett et al.   HUMAN MOLECULAR GENETICS

Novel Role for p90 Ribosomal S6 Kinase in the Regulation of Cardiac Myofilament Phosphorylation

(2010) Friederike Cuello et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myosin Binding Protein C Interaction with Actin

(2010) Inna N. Rybakova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β

(2010) Polakit Teekakirikul et al.   JOURNAL OF CLINICAL INVESTIGATION

Analysis of cardiac myosin binding protein-C phosphorylation in human heart muscle

(2010) O'Neal Copeland et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy

(2010) Anita C. Hoskins et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Rescue of familial cardiomyopathies by modifications at the level of sarcomere and Ca2+ fluxes

(2010) Marco L. Alves et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Neonatal gene transfer of Serca2a delays onset of hypertrophic remodeling and improves function in familial hypertrophic cardiomyopathy

(2010) James R. Peña et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Differential roles of regulatory light chain and myosin binding protein-C phosphorylations in the modulation of cardiac force development

(2010) Brett A. Colson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Identification of Novel Protein Kinase A Phosphorylation Sites in the M-domain of Human and Murine Cardiac Myosin Binding Protein-C Using Mass Spectrometry Analysis

(2010) Weitao Jia et al.   JOURNAL OF PROTEOME RESEARCH

Myocardial Fibrosis as an Early Manifestation of Hypertrophic Cardiomyopathy

(2010) Carolyn Y. Ho et al.   NEW ENGLAND JOURNAL OF MEDICINE

Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms

(2009) Giulia Mearini et al.   CARDIOVASCULAR RESEARCH

Cardiac Myosin Binding Protein-C Phosphorylation in a β-Myosin Heavy Chain Background

(2009) Sakthivel Sadayappan et al.   CIRCULATION

Cardiac Myosin-Binding Protein C Mutations and Hypertrophic Cardiomyopathy

(2009) Sabine J. van Dijk et al.   CIRCULATION

Nonsense-Mediated mRNA Decay and Ubiquitin–Proteasome System Regulate Cardiac Myosin-Binding Protein C Mutant Levels in Cardiomyopathic Mice

(2009) Nicolas Vignier et al.   CIRCULATION RESEARCH

Evidence From Human Myectomy Samples That MYBPC3 Mutations Cause Hypertrophic Cardiomyopathy Through Haploinsufficiency

(2009) Steven Marston et al.   CIRCULATION RESEARCH

Relation of functional and morphological changes in mitochondria to myocardial contractile and relaxation reserves in asymptomatic to mildly symptomatic patients with hypertrophic cardiomyopathy

(2009) Kazumasa Unno et al.   EUROPEAN HEART JOURNAL

Distinct Sarcomeric Substrates Are Responsible for Protein Kinase D-mediated Regulation of Cardiac Myofilament Ca2+Sensitivity and Cross-bridge Cycling

(2009) Sonya C. Bardswell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation and function of cardiac myosin binding protein-C in health and disease

(2009) David Barefield et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

From genotype to phenotype: a longitudinal study of a patient with hypertrophic cardiomyopathy due to a mutation in the MYBPC3 gene

(2009) Adam Jacques et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Obscurin Interacts with a Novel Isoform of MyBP-C Slow at the Periphery of the Sarcomeric M-Band and Regulates Thick Filament Assembly

(2009) Maegen A. Ackermann et al.   MOLECULAR BIOLOGY OF THE CELL

A common MYBPC3 (cardiac myosin binding protein C) variant associated with cardiomyopathies in South Asia

(2009) Perundurai S Dhandapany et al.   NATURE GENETICS

Muscle Giants: Molecular Scaffolds in Sarcomerogenesis

(2009) Aikaterini Kontrogianni-Konstantopoulos et al.   PHYSIOLOGICAL REVIEWS

Acceleration of Crossbridge Kinetics by Protein Kinase A Phosphorylation of Cardiac Myosin Binding Protein C Modulates Cardiac Function

(2008) Carl W. Tong et al.   CIRCULATION RESEARCH

Understanding the Organisation and Role of Myosin Binding Protein C in Normal Striated Muscle by Comparison with MyBP-C Knockout Cardiac Muscle

(2008) Pradeep K. Luther et al.   JOURNAL OF MOLECULAR BIOLOGY

Calcium Cycling and Signaling in Cardiac Myocytes

(2007) Donald M. Bers   Annual Review of Physiology