Pharmacologic Studies of a Prodrug of Mitomycin C in Pegylated Liposomes (Promitil®): High Stability in Plasma and Rapid Thiolytic Prodrug Activation in Tissues

Pegylated liposomal mitomycin C prodrug enhances tolerance of mitomycin C: a phase 1 study in advanced solid tumor patients

(2015) Talia Golan et al.   Cancer Medicine

Mitomycinoid Alkaloids: Mechanism of Action, Biosynthesis, Total Syntheses, and Synthetic Approaches

(2013) Phillip D. Bass et al.   CHEMICAL REVIEWS

The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo

(2012) Hiroshi Maeda et al.   ADVANCED DRUG DELIVERY REVIEWS

A New Mechanism of Action for the Anticancer Drug Mitomycin C: Mechanism-Based Inhibition of Thioredoxin Reductase

(2012) Manuel M. Paz et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Pharmacological basis of pegylated liposomal doxorubicin: Impact on cancer therapy

(2011) Alberto Gabizon et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Therapeutic efficacy of a lipid-based prodrug of mitomycin C in pegylated liposomes: Studies with human gastro-entero-pancreatic ectopic tumor models

(2011) Alberto Gabizon et al.   JOURNAL OF CONTROLLED RELEASE

The effects of particle size, density and shape on margination of nanoparticles in microcirculation

(2011) Randall Toy et al.   NANOTECHNOLOGY

Cross-Linking of Dithiols by Mitomycin C

(2010) Manuel M. Paz   CHEMICAL RESEARCH IN TOXICOLOGY

Delivery of zoledronic acid encapsulated in folate-targeted liposome results in potent in vitro cytotoxic activity on tumor cells

(2010) Hilary Shmeeda et al.   JOURNAL OF CONTROLLED RELEASE

Personalizing Cancer Treatment in the Age of Global Genomic Analyses: PALB2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer

(2010) M. C. Villarroel et al.   MOLECULAR CANCER THERAPEUTICS

Reductive Activation of Mitomycin C by Thiols: Kinetics, Mechanism, and Biological Implications

(2009) Manuel M. Paz   CHEMICAL RESEARCH IN TOXICOLOGY