Targeting autophagy in skin diseases

Combined MTOR and autophagy inhibition

(2014) Reshma Rangwala et al.   Autophagy

Autophagy induced by resveratrol suppressesα-MSH-induced melanogenesis

(2014) Eun Sung Kim et al.   EXPERIMENTAL DERMATOLOGY

Regulation of autophagy: Modulation of the size and number of autophagosomes

(2014) Meiyan Jin et al.   FEBS LETTERS

Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma

(2014) Xiao-Hong Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy in Antimicrobial Immunity

(2014) Ligia C. Gomes et al.   MOLECULAR CELL

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Management of Skin Abscesses in the Era of Methicillin-Resistant Staphylococcus aureus

(2014) Adam J. Singer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy inDrosophila: From Historical Studies to Current Knowledge

(2014) Nitha C. Mulakkal et al.   Biomed Research International

Autophagy-Mediated Tumor Promotion

(2013) Jessie Yanxiang Guo et al.   CELL

The Globally Disseminated M1T1 Clone of Group A Streptococcus Evades Autophagy for Intracellular Replication

(2013) Timothy C. Barnett et al.   Cell Host & Microbe

Autophagy plays a WASHing game

(2013) Nicolas Dupont et al.   EMBO JOURNAL

ARP101 inhibits α-MSH-stimulated melanogenesis by regulation of autophagy in melanocytes

(2013) Eun Sung Kim et al.   FEBS LETTERS

Hydroxychloroquine preferentially induces apoptosis of CD45RO+ effector T cells by inhibiting autophagy: A possible mechanism for therapeutic modulation of T cells

(2013) Jorg van Loosdregt et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Fine mapping of autophagy-related proteins during autophagosome formation in Saccharomyces cerevisiae

(2013) K. Suzuki et al.   JOURNAL OF CELL SCIENCE

Autophagy Is Induced by UVA and Promotes Removal of Oxidized Phospholipids and Protein Aggregates in Epidermal Keratinocytes

(2013) Yi Zhao et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Autophagy Has a Significant Role in Determining Skin Color by Regulating Melanosome Degradation in Keratinocytes

(2013) Daiki Murase et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

How Positive-Strand RNA Viruses Benefit from Autophagosome Maturation

(2013) A. L. Richards et al.   JOURNAL OF VIROLOGY

Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

(2013) Jaime Anguiano et al.   Nature Chemical Biology

The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

Autophagy in Human Health and Disease

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Rapamycin Upregulates Autophagy by Inhibiting the mTOR-ULK1 Pathway, Resulting in Reduced Podocyte Injury

(2013) Lingling Wu et al.   PLoS One

Human papillomavirus infection is inhibited by host autophagy in primary human keratinocytes

(2013) Laura M. Griffin et al.   VIROLOGY

Autophagy prevents irradiation injury and maintains stemness through decreasing ROS generation in mesenchymal stem cells

(2013) J Hou et al.   Cell Death & Disease

Polymorphisms in the ATG16L1 Gene are Associated with Psoriasis Vulgaris

(2012) K Douroudis et al.   ACTA DERMATO-VENEREOLOGICA

Autophagy as a Stress-Response and Quality-Control Mechanism: Implications for Cell Injury and Human Disease

(2012) Lyndsay Murrow et al.   Annual Review of Pathology-Mechanisms of Disease

Cytosolic clearance of replication-deficient mutants revealsFrancisella tularensisinteractions with the autophagic pathway

(2012) Audrey Chong et al.   Autophagy

Macroautophagy is deregulated in murine and human lupus T lymphocytes

(2012) Frédéric Gros et al.   Autophagy

Cell type-dependent requirement of autophagy in HSV-1 antiviral defense

(2012) Brian Yordy et al.   Autophagy

Autophagy in periodontitis patients and gingival fibroblasts: unraveling the link between chronic diseases and inflammation

(2012) Pedro Bullon et al.   BMC Medicine

Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway

(2012) Robert O. Watson et al.   CELL

Autophagy and cancer

(2012) Kyeong Sook Choi   EXPERIMENTAL AND MOLECULAR MEDICINE

T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy

(2012) Cristiano Alessandri et al.   FASEB JOURNAL

Macrophage Autophagy in Immunity to Cryptococcus neoformans and Candida albicans

(2012) André Moraes Nicola et al.   INFECTION AND IMMUNITY

Autophagy Controls p38 Activation to Promote Cell Survival under Genotoxic Stress

(2012) Lei Qiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

Autophagy Inhibitor Chloroquine Enhanced the Cell Death Inducing Effect of the Flavonoid Luteolin in Metastatic Squamous Cell Carcinoma Cells

(2012) Lien Verschooten et al.   PLoS One

LC3A-Positive “Stone-Like” Structures in Cutaneous Squamous Cell Carcinomas

(2011) Efthimios Sivridis et al.   AMERICAN JOURNAL OF DERMATOPATHOLOGY

Defective Regulation of Autophagy upon Leucine Deprivation Reveals a Targetable Liability of Human Melanoma Cells In Vitro and In Vivo

(2011) Joon-Ho Sheen et al.   CANCER CELL

Punctate LC3B Expression Is a Common Feature of Solid Tumors and Associated with Proliferation, Metastasis, and Poor Outcome

(2011) R. Lazova et al.   CLINICAL CANCER RESEARCH

Measurements of Tumor Cell Autophagy Predict Invasiveness, Resistance to Chemotherapy, and Survival in Melanoma

(2011) X.-H. Ma et al.   CLINICAL CANCER RESEARCH

p62 and NDP52 Proteins Target IntracytosolicShigellaandListeriato Different Autophagy Pathways

(2011) Serge Mostowy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcipotriol Induces Autophagy in HeLa Cells and Keratinocytes

(2011) Richard C. Wang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

(2011) S. Alers et al.   MOLECULAR AND CELLULAR BIOLOGY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Autophagy differentially controls plant basal immunity to biotrophic and necrotrophic pathogens

(2011) Heike D. Lenz et al.   PLANT JOURNAL

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

(2011) P. Wild et al.   SCIENCE

Functional Analysis of Host Factors that Mediate the Intracellular Lifestyle of Cryptococcus neoformans

(2011) Qing-Ming Qin et al.   PLoS Pathogens

Autophagy: A target for retinoic acids

(2010) Yogendra Rajawat et al.   Autophagy

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Association of UVRAG polymorphisms with susceptibility to non-segmental vitiligo in a Korean sample

(2010) Taek-Jo Jeong et al.   EXPERIMENTAL DERMATOLOGY

In Vivo Requirement for Atg5 in Antigen Presentation by Dendritic Cells

(2010) Heung Kyu Lee et al.   IMMUNITY

Autophagy Negatively Regulates Keratinocyte Inflammatory Responses via Scaffolding Protein p62/SQSTM1

(2010) H.-M. Lee et al.   JOURNAL OF IMMUNOLOGY

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Genetic Factors Predisposing to Systemic Lupus Erythematosus and Lupus Nephritis

(2010) Paula S. Ramos et al.   SEMINARS IN NEPHROLOGY

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL

The Double-Edged Sword of Autophagy Modulation in Cancer

(2009) E. White et al.   CLINICAL CANCER RESEARCH

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

(2009) Vesela Gateva et al.   NATURE GENETICS

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

(2009) Jian-Wen Han et al.   NATURE GENETICS

Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection

(2009) Luc English et al.   NATURE IMMUNOLOGY

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Eating the enemy within: autophagy in infectious diseases

(2008) A Orvedahl et al.   CELL DEATH AND DIFFERENTIATION

Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens

(2008) Zijiang Zhao et al.   Cell Host & Microbe

Autophagy and pattern recognition receptors in innate immunity

(2008) Monica Delgado et al.   IMMUNOLOGICAL REVIEWS

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking

(2008) Chengyu Liang et al.   NATURE CELL BIOLOGY