Amphiphysin 2 (BIN1) in physiology and diseases

EHD1 mediates vesicle trafficking required for normal muscle growth and transverse tubule development

(2014) Avery D. Posey et al.   DEVELOPMENTAL BIOLOGY

The myotubularin–amphiphysin 2 complex in membrane tubulation and centronuclear myopathies

(2013) Barbara Royer et al.   EMBO REPORTS

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

(2013) J Chapuis et al.   MOLECULAR PSYCHIATRY

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Bridging integrator 1 (BIN1): form, function, and Alzheimer's disease

(2013) Meng-Shan Tan et al.   TRENDS IN MOLECULAR MEDICINE

Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system

(2013) Etienne Morel et al.   Nature Communications

Altered Splicing of the BIN1 Muscle-Specific Exon in Humans and Dogs with Highly Progressive Centronuclear Myopathy

(2013) Johann Böhm et al.   PLoS Genetics

Alzheimer Disease Susceptibility Loci: Evidence for a Protein Network under Natural Selection

(2012) Towfique Raj et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Interaction of amphiphysins with AP-1 clathrin adaptors at the membrane

(2012) Sonja Huser et al.   BIOCHEMICAL JOURNAL

Exploration of deleterious single nucleotide polymorphisms in late-onset Alzheimer disease susceptibility genes

(2012) Tariq Ahmad Masoodi et al.   GENE

BIN1: A new biomarker to track ARVC?

(2012) Angeliki Asimaki   HEART RHYTHM

Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy

(2012) Ting-Ting Hong et al.   HEART RHYTHM

Tissue-Specific Alternative Splicing Remodels Protein-Protein Interaction Networks

(2012) Jonathan D. Ellis et al.   MOLECULAR CELL

Myotubularin phosphoinositide phosphatases: cellular functions and disease pathophysiology

(2012) Karim Hnia et al.   TRENDS IN MOLECULAR MEDICINE

Insights into Alzheimer disease pathogenesis from studies in transgenic animal models

(2011) Evelin L. Schaeffer et al.   Clinics

BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes

(2011) Ting-Ting Hong et al.   HEART RHYTHM

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy

(2011) Charlotte Fugier et al.   NATURE MEDICINE

Evidence of the association of BIN1 and PICALM with the AD risk in contrasting European populations

(2011) Jean-Charles Lambert et al.   NEUROBIOLOGY OF AGING

Meta-Analysis for Genome-Wide Association Study Identifies Multiple Variants at the BIN1 Locus Associated with Late-Onset Alzheimer's Disease

(2011) Xiaolan Hu et al.   PLoS One

Disrupted Membrane Structure and Intracellular Ca2+ Signaling in Adult Skeletal Muscle with Acute Knockdown of Bin1

(2011) Andoria Tjondrokoesoemo et al.   PLoS One

c-MYC Suppresses BIN1 to Release Poly(ADP-Ribose) Polymerase 1: A Mechanism by Which Cancer Cells Acquire Cisplatin Resistance

(2011) S. Pyndiah et al.   Science Signaling

Centronuclear Myopathies

(2011) Norma B. Romero et al.   Seminars in Pediatric Neurology

A High Precision Survey of the Molecular Dynamics of Mammalian Clathrin-Mediated Endocytosis

(2011) Marcus J. Taylor et al.   PLOS BIOLOGY

Genome-Wide Association of Familial Late-Onset Alzheimer's Disease Replicates BIN1 and CLU and Nominates CUGBP2 in Interaction with APOE

(2011) Ellen M. Wijsman et al.   PLoS Genetics

Defects in amphiphysin 2 (BIN1) and triads in several forms of centronuclear myopathies

(2010) Anne Toussaint et al.   ACTA NEUROPATHOLOGICA

Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease

(2010) Sudha Seshadri   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

PHENOTYPE OF A PATIENT WITH RECESSIVE CENTRONUCLEAR MYOPATHY AND A NOVEL BIN1 MUTATION

(2010) K. G. Claeys et al.   NEUROLOGY

Case report of intrafamilial variability in autosomal recessive centronuclear myopathy associated to a novel BIN1 stop mutation

(2010) Johann Böhm et al.   Orphanet Journal of Rare Diseases

From Dynamic Live Cell Imaging to 3D Ultrastructure: Novel Integrated Methods for High Pressure Freezing and Correlative Light-Electron Microscopy

(2010) Coralie Spiegelhalter et al.   PLoS One

BIN1 Localizes the L-Type Calcium Channel to Cardiac T-Tubules

(2010) Ting-Ting Hong et al.   PLOS BIOLOGY

Identification of tyrosine kinase, HCK, and tumor suppressor, BIN1, as potential mediators ofAHI-1oncogene in primary and transformed CTCL cells

(2009) Erin Kennah et al.   BLOOD

The BAR Domain Superfamily: Membrane-Molding Macromolecules

(2009) Adam Frost et al.   CELL

The c-MYC-interacting proapoptotic tumor suppressor BIN1 is a transcriptional target for E2F1 in response to DNA damage

(2009) E K Cassimere et al.   CELL DEATH AND DIFFERENTIATION

Dynamic Interaction of Amphiphysin with N-WASP Regulates Actin Assembly

(2009) Hiroshi Yamada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bin1 Src Homology 3 Domain Acts as a Scaffold for Myofiber Sarcomere Assembly

(2009) Pasan Fernando et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivoPhosphoproteome of Human Skeletal Muscle Revealed by Phosphopeptide Enrichment and HPLC−ESI−MS/MS

(2009) Kurt Højlund et al.   JOURNAL OF PROTEOME RESEARCH

AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling

(2009) Saumya Pant et al.   NATURE CELL BIOLOGY

Bin1 is linked to metastatic potential and chemosensitivity in neuroblastoma

(2009) Xiaoling Zhong et al.   PEDIATRIC BLOOD & CANCER

The membrane-tubulating potential of amphiphysin 2/BIN1 is dependent on the microtubule-binding cytoplasmic linker protein 170 (CLIP-170)

(2008) Brigitte Meunier et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Adenovirus E1A oncoprotein liberates c‐Myc activity to promote cell proliferation through abating Bin1 expression via an Rb/E2F1‐dependent mechanism

(2008) Erica L. Kinney et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Protein phosphorylation is required for endocytosis in nerve terminals: potential role for the dephosphins dynamin I and synaptojanin, but not AP180 or amphiphysin

(2003) Michael A. Cousin et al.   JOURNAL OF NEUROCHEMISTRY