Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products

Synergistic killing effect of imatinib and simvastatin on imatinib-resistant chronic myelogenous leukemia cells

(2012) Bora Oh et al.   ANTI-CANCER DRUGS

Lactobacillus acidophilus ameliorates H. pylori-induced gastric inflammation by inactivating the Smad7 and NFκB pathways

(2012) Yao-Jong Yang et al.   BMC MICROBIOLOGY

Eliminating drug resistant breast cancer stem-like cells with combination of simvastatin and gamma-tocotrienol

(2012) Archana Gopalan et al.   CANCER LETTERS

Simvastatin inhibition of mevalonate pathway induces apoptosis in human breast cancer cells via activation of JNK/CHOP/DR5 signaling pathway

(2012) Archana Gopalan et al.   CANCER LETTERS

Effects of statins and farnesyl transferase inhibitors on ERK phosphorylation, apoptosis and cell viability in non-small lung cancer cells

(2012) G. Pelaia et al.   CELL PROLIFERATION

First Evidence That  -Tocotrienol Inhibits the Growth of Human Gastric Cancer and Chemosensitizes It to Capecitabine in a Xenograft Mouse Model through the Modulation of NF- B Pathway

(2012) K. A. Manu et al.   CLINICAL CANCER RESEARCH

Common cancer risk and statins: a population-based case–control study in a Chinese population

(2012) Henry WC Leung et al.   Expert Opinion On Drug Safety

Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer

(2012) Lalitha Ramachandran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Simvastatin Induces Apoptosis in Castrate Resistant Prostate Cancer Cells by Deregulating Nuclear Factor-κB Pathway

(2012) Yong Hyun Park et al.   JOURNAL OF UROLOGY

A Randomized Phase II Study of Gefitinib Plus Simvastatin Versus Gefitinib Alone in Previously Treated Patients with Advanced Non–Small Cell Lung Cancer

(2011) Ji-Youn Han et al.   CLINICAL CANCER RESEARCH

Simvastatin stimulates apoptosis in cholangiocarcinoma by inhibition of Rac1 activity

(2011) Timothy Miller et al.   DIGESTIVE AND LIVER DISEASE

Involvement of Chk1–Cdc25A-cyclin A/CDk2 pathway in simvastatin induced S-phase cell cycle arrest and apoptosis in multiple myeloma cells

(2011) Yong-Sheng Tu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell 'stemness' via the bone morphogenetic protein pathway

(2011) L. L. Kodach et al.   GUT

Effect of Simvastatin on Cetuximab Resistance in Human Colorectal Cancer With KRAS Mutations

(2011) Jeeyun Lee et al.   JNCI-Journal of the National Cancer Institute

Statin therapy attenuates growth and malignant potential of human esophageal adenocarcinoma cells

(2011) Miral R. Sadaria et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

A Gene Expression Signature of Acquired Chemoresistance to Cisplatin and Fluorouracil Combination Chemotherapy in Gastric Cancer Patients

(2011) Hark Kyun Kim et al.   PLoS One

A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis

(2010) S Y Nam et al.   BRITISH JOURNAL OF CANCER

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Simvastatin inhibits cell growth and induces apoptosis and G0/G1 cell cycle arrest in hepatic cancer cells

(2010) Relja   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Simvastatin modulates the adhesion and growth of hepatocellular carcinoma cells via decrease of integrin expression and ROCK

(2010) Relja   INTERNATIONAL JOURNAL OF ONCOLOGY

Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway

(2010) Yasuhiro Kidera et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Anticancer Efficacy of Simvastatin on Prostate Cancer Cells and Tumor Xenografts Is Associated with Inhibition of Akt and Reduced Prostate-Specific Antigen Expression

(2010) S. T. Kochuparambil et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Potential pharmacological control of the NF-κB pathway

(2009) Gautam Sethi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Simvastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, suppresses osteoclastogenesis induced by receptor activator of nuclear factor-κB ligand through modulation of NF-κB pathway

(2008) Kwang Seok Ahn et al.   INTERNATIONAL JOURNAL OF CANCER

Combination regimen with statins and NSAIDs: A promising strategy for cancer chemoprevention

(2008) Hang Xiao et al.   INTERNATIONAL JOURNAL OF CANCER

Effects of Wei Chang An on expression of multiple genes in human gastric cancer grafted onto nude mice

(2008) Ai-Guang Zhao   WORLD JOURNAL OF GASTROENTEROLOGY

Nuclear factor kappa B: A marker of chemotherapy for human stage IV gastric carcinoma

(2008) Sheng Ye et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Reversal of chemoresistance and enhancement of apoptosis by statins through down-regulation of the NF-κB pathway

(2007) Kwang Seok Ahn et al.   BIOCHEMICAL PHARMACOLOGY