IL-17 producing T cells in mouse models of multiple sclerosis and rheumatoid arthritis

IL-27 mediates the response to IFN-β therapy in multiple sclerosis patients by inhibiting Th17 cells

(2011) Cheryl M. Sweeney et al.   BRAIN BEHAVIOR AND IMMUNITY

Th17 Cells, Not IL-17+    T Cells, Drive Arthritic Bone Destruction in Mice and Humans

(2011) B. Pollinger et al.   JOURNAL OF IMMUNOLOGY

Fate mapping of IL-17-producing T cells in inflammatory responses

(2011) Keiji Hirota et al.   NATURE IMMUNOLOGY

Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production

(2010) J. P. van Hamburg et al.   ARTHRITIS AND RHEUMATISM

Synovial fluid-derived T helper 17 cells correlate with inflammatory activity in arthritis, irrespectively of diagnosis

(2010) Gaetano Zizzo et al.   CLINICAL IMMUNOLOGY

γδ T Cells Enhance Autoimmunity by Restraining Regulatory T Cell Responses via an Interleukin-23-Dependent Mechanism

(2010) Franziska Petermann et al.   IMMUNITY

Memory CD4+CD127high T cells from patients with multiple sclerosis produce IL-17 in response to myelin antigens

(2010) Koen Venken et al.   JOURNAL OF NEUROIMMUNOLOGY

T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis

(2010) Robert C Axtell et al.   NATURE MEDICINE

Proinflammatory T helper type 17 cells are effective B-cell helpers

(2010) M. Mitsdoerffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-β

(2009) Luca Durelli et al.   ANNALS OF NEUROLOGY

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis

(2009) Yoshinaga Ito et al.   ARTHRITIS AND RHEUMATISM

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells

(2009) Bernadette Pöllinger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IFN-  Inhibits Human Th17 Cell Differentiation

(2009) V. S. Ramgolam et al.   JOURNAL OF IMMUNOLOGY

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

Interleukin 17 acts in synergy with B cell–activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus

(2009) Agnès Doreau et al.   NATURE IMMUNOLOGY

Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis

(2009) Gurumoorthy Krishnamoorthy et al.   NATURE MEDICINE

Cartilage oligomeric matrix protein induction of chronic arthritis in mice

(2008) Stefan Carlsen et al.   ARTHRITIS AND RHEUMATISM

Naïve CD8 T-cells initiate spontaneous autoimmunity to a sequestered model antigen of the central nervous system

(2008) Shin-Young Na et al.   BRAIN

Oligoclonal myelin-reactive T-cell infiltrates derived from multiple sclerosis lesions are enriched in Th17 cells

(2008) Monica Montes et al.   CLINICAL IMMUNOLOGY

T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis

(2008) Chris J. Hedegaard et al.   IMMUNOLOGY

Regulation of inflammatory responses by IL-17F

(2008) Xuexian O. Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis

(2007) John S. Tzartos et al.   AMERICAN JOURNAL OF PATHOLOGY