The nutraceutical flavonoid luteolin inhibits ADAMTS-4 and ADAMTS-5 aggrecanase activities

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Distribution and Biological Activities of the Flavonoid Luteolin

(2009) Miguel Lopez-Lazaro   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Nobiletin, a citrus polymethoxy flavonoid, suppresses gene expression and production of aggrecanases-1 and -2 in collagen-induced arthritic mice

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Luteolin inhibits proliferation and affects the function of stimulated rat synovial fibroblasts

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Elucidating the Function of Non catalytic Domains of Collagenases and Aggrecanases

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Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases

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Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1

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Drug Insight: aggrecanases as therapeutic targets for osteoarthritis

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Screening of potential a disintegrin and metalloproteinase with thrombospondin motifs-4 inhibitors using a collagen model fluorescence resonance energy transfer substrate

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