Temperature-sensitive bacterial pathogens generated by the substitution of essential genes from cold-loving bacteria: potential use as live vaccines

Genes that move the window of viability of life: Lessons from bacteria thriving at the cold extreme

(2010) Víctor de Lorenzo   BIOESSAYS

Essential genes from Arctic bacteria used to construct stable, temperature-sensitive bacterial vaccines

(2010) B. N. Duplantis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reintroduction of Two Deleted Virulence Loci Restores Full Virulence to the Live Vaccine Strain of Francisella tularensis

(2009) E. Salomonsson et al.   INFECTION AND IMMUNITY

Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge with Mycobacterium tuberculosis

(2009) Ronggai Sun et al.   VACCINE

Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates

(2009) Michelle H. Larsen et al.   VACCINE

A complete collection of single-gene deletion mutants of Acinetobacter baylyi ADP1

(2008) Véronique de Berardinis et al.   Molecular Systems Biology

Protective efficacy of recombinant BCG Tokyo (Ag85A) in rhesus monkeys (Macaca mulatta) infected intratracheally with H37Rv Mycobacterium tuberculosis

(2008) I. Sugawara et al.   TUBERCULOSIS