Article
Biochemistry & Molecular Biology
Abdul Ahad, Faiyaz Shakeel, Mohammad Raish, Ajaz Ahmad, Yousef A. Bin Jardan, Fahad I. Al-Jenoobi, Abdullah M. Al-Mohizea
Summary: The solubility parameters and solution thermodynamics of temozolomide in 10 commonly used solvents were investigated, identifying dimethyl sulfoxide as the most suitable solvent for dissolving temozolomide. The findings can provide guidance for the formulation and processes involving temozolomide.
Article
Thermodynamics
Abdul Ahad, Faiyaz Shakeel, Mohammad Raish, Ajaz Ahmad, Yousef A. Bin Jardan, Fahad Al-Jenoobi, Abdullah M. Al-Mohizea
Summary: This study investigated the solubility and dissolution thermodynamic parameters of vinpocetine in different solvents, finding lower solubility in water and better solubility in non-polar solvents. The Van't Hoff equation was more precise in correlating the solubilities of vinpocetine in the investigated solvents. Enormous support was provided for vinpocetine solubilization, pre-formulation, and dosage form development in pharmaceuticals.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2022)
Article
Chemistry, Physical
Anna Garibyan, Ekaterina Delyagina, Mikhail Agafonov, Ilya Khodov, Irina Terekhova
Summary: Baricitinib's solubility was found to be pH dependent, with slight solubility at pH 4-12 and better solubility in acidic and strongly alkaline media. The use of cyclodextrins improved the physicochemical properties of baricitinib, and the formation of host-guest complexes was studied. The influence of cyclodextrin structure and baricitinib's ionization state on complex formation and the impact of cyclodextrins on solubility and membrane permeability were analyzed.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Editorial Material
Chemistry, Physical
William E. Acree, Evonne R. Huang, Kelly Kim
Summary: The author presents a polemic regarding the goodness-of-fit values of the predictive expressions used to describe the solubility data of stearic acid. By averaging relative deviations, positive and negative deviations cancel in the van't Hoff model, while the absolute values of deviations are averaged in the modified Apelblat model.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Editorial Material
Chemistry, Physical
William E. Acree, Neel Shanmugam, Pranavi Garlapati
Summary: A polemic discussion is presented on the curve-fit equation coefficients for van't Hoff and Modified Apelblat equations, as well as the apparent thermodynamic properties of rifampicin dissolution in various solvents.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Physical
Zilong Cui, Zhiruo Zhao, Liang Yao, Yonghong Hu
Summary: The study aims to provide energetics data for industrial production of brassinolide, testing solid-liquid equilibrium in different solvents and solvent mixtures. Tetrahydrofuran is found to be a better organic solvent, while n-hexane can be effective as an anti-solvent for separating brassinolides.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Thermodynamics
Mohammed Majrashi, Ahmed Salah Al-Shati, Maria Grishina, Shaheen M. Sarkar, Minh-Tri Nguyen-Le, Saeed Shirazian
Summary: Chlorothiazide, a diuretic and antihypertensive drug, has low solubility and bioavailability. Using a supercritical carbon dioxide method to reduce the particle size to micro/nano scale can enhance its bioavailability and therapeutic efficiency.
CASE STUDIES IN THERMAL ENGINEERING
(2023)
Article
Chemistry, Physical
Larissa dos Santos Silva Araujo, Giuseppe Lazzara, Leonardo Chiappisi
Summary: This study provides a comprehensive overview of the thermodynamics aspects of surfactants and CDs inclusion complexes formation in aqueous environment, emphasizing the assessment of interactions, thermodynamic driving forces, and structural aspects. It also discusses the most common analytical techniques used to gather deep insight into CDs complexes, pointing out the perspectives for the surfactant-cyclodextrin complexes.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2021)
Review
Medicine, Research & Experimental
Vasanti Suvarna, Bhunesh Bore, Chaitanya Bhawar, Rashmi Mallya
Summary: Bioactive phytochemicals from natural sources have diverse therapeutic activities, but their application is hindered by drawbacks such as poor solubility and bioavailability. However, complexation with cyclodextrins provides a solution to these issues. This article summarizes the complexation of various phytochemicals with cyclodextrins and the impact on their stability and dissolution rate, leading to enhanced bioactivity.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Chemistry, Multidisciplinary
Cecilie Hogfeldt Jessen, Jesper Bendix, Theis Brock Nannestad, Heloisa N. N. Bordallo, Martin Jaeger Pedersen, Christian Marcus Pedersen, Mikael Bols
Summary: α-cyclodextrin dissolved in water forms a 1:1 complex with methane, yielding crystals with a maximum yield of 57%. The binding constant is K-a=21 (±1.0) M-1. 3(A),6(A),3(D),6(D)-dianhydro-α-cyclodextrin, which has a smaller cavity than α-cyclodextrin, binds methane three times better with a binding constant of K-a=75 (±25) M-1.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Physical
Amy Oo, Panupong Mahalapbutr, Kuakarun Krusong, Ponsiri Liangsakul, Sariyarach Thanasansurapong, Vichai Reutrakul, Chutima Kuhakarn, Phornphimon Maitarad, Atit Silsirivanit, Peter Wolschann, Siyaporn Putthisen, Khanittha Kerdpol, Thanyada Rungrotmongkol
Summary: Encapsulation with beta-cyclodextrin (β-CD) has been explored to enhance the solubility of emodin (ED) for pharmaceutical applications. In this study, inclusion complexation of ED with β-CD and its derivatives was performed to identify the most promising drug carrier. The ED/DM-β-CD complex showed the highest stability and water solubility, followed by ED/SBE7-β-CD and ED/HP-β-CD complexes. The SEM micrographs and DSC thermograms confirmed the inclusion complex formation, and molecular docking suggested C-form insertion as the preferred binding mode. Moreover, the inclusion complexes, especially ED/DM-β-CD, showed significantly higher anti-proliferative effects on cancer cell lines compared to ED alone.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Polymer Science
Yuta Aoki, Stephen Wu, Teruki Tsurimoto, Yoshihiro Hayashi, Shunya Minami, Okubo Tadamichi, Kazuya Shiratori, Ryo Yoshida
Summary: This article presents a machine learning approach to predict phase equilibria in polymer-solvent solutions, demonstrating the model's wide applicability and high predictive power.
Article
Chemistry, Applied
Hyun-Mo Jeong, Yeontaek Lee, Yu-Jeong Shin, Seung-Hye Woo, Ji-Soo Kim, Da-Woon Jeong, Sooyong Shin, Sung Ho Jeon, Jae-Hoon Shim
Summary: A novel encapsulation process based on the cyclization activity of CGTase was developed to encapsulate resveratrol in cyclodextrins, significantly increasing its water solubility. Experimental results showed that CA-RVT in aqueous solution exhibited similar activities as an equal amount of RVT in dimethyl sulfoxide.
Review
Engineering, Chemical
Wenju Liu, Zehua Bao, Yanmin Shen, Tiantian Yao, Hongjuan Bai, Xinyu Jin
Summary: In this study, the solubility of carbamazepine (CBZ) (form III) in various solvents was determined using laser monitoring techniques. The results showed that solubility increased with temperature and experimental values were in good agreement with simulated values.
CHINESE JOURNAL OF CHEMICAL ENGINEERING
(2021)
Article
Chemistry, Analytical
Silvia Navarro-Orcajada, Irene Conesa, Adrian Matencio, Pilar Rodriguez-Bonilla, Francisco Garcia-Carmona, Jose Manuel Lopez-Nicolas
Summary: The ability of cyclodextrins to enhance water solubility of lipophilic compounds can interfere with fluorescent readings, leading to contradictory results. The encapsulation of other substrates in the reaction is the main cause of this interference.
Article
Chemistry, Medicinal
Md. Khalid Anwer, Mohammed Muqtader Ahmed, Mohammed F. Aldawsari, Muzaffar Iqbal, Vinay Kumar
Summary: In this study, DSM-loaded beta-CD-based nanosponges were prepared using DPC as a cross-linker. The optimized NSPs (D-NSP3) showed improved free radical scavenging activity and dissolution efficiency compared to pure DSM. Additionally, D-NSP3 exhibited cytotoxic activity against MCF-7 breast cancer cells. These findings suggest that DSM-loaded NSPs might be a promising therapy option for breast cancer.
Review
Biochemistry & Molecular Biology
Sukhbir Singh, Neelam Sharma, Saurabh Shukla, Tapan Behl, Sumeet Gupta, Md. Khalid Anwer, Celia Vargas-De-La-Cruz, Simona Gabriela Bungau, Cristina Brisc
Summary: This article summarizes the epidemiology of chronic liver disease, the pathogenesis and pathophysiology of liver fibrosis, the symptoms of liver fibrosis progression and regression, the clinical evaluation of liver fibrosis, and the research into nanotechnology-based synthetic and herbal treatments for liver fibrosis. The herbal remedies mentioned include epigallocathechin-3-gallate, silymarin, oxymatrine, curcumin, tetrandrine, glycyrrhetinic acid, salvianolic acid, plumbagin, Scutellaria baicalnsis Georgi, astragalosides, hawthorn extract, and andrographolides.
Article
Biochemistry & Molecular Biology
Wafa K. Fatani, Fadilah S. Aleanizy, Fulwah Y. Alqahtani, Mohammed M. Alanazi, Abdullah A. Aldossari, Faiyaz Shakeel, Nazrul Haq, Hosam Abdelhady, Hamad M. Alkahtani, Ibrahim A. Alsarra
Summary: Lung cancer is the leading cause of cancer-related deaths worldwide. Erlotinib, a tyrosine kinase inhibitor, has been explored as a potential treatment for lung cancer. Researchers have formulated two different generations of polyamidoamine (PAMAM) dendrimers and evaluated their efficacy in delivering erlotinib. The results showed that the cationic G4 dendrimer had higher selectivity and antiproliferative activity against lung cancer cells compared to the neutral G5 dendrimer and erlotinib alone, suggesting its potential as a targeted and sustained release carrier for erlotinib.
Editorial Material
Biochemistry & Molecular Biology
Faiyaz Shakeel
Review
Biochemistry & Molecular Biology
Sukhbir Singh, Sonam Grewal, Neelam Sharma, Tapan Behl, Sumeet Gupta, Md. Khalid Anwer, Celia Vargas-De-La-Cruz, Syam Mohan, Simona Gabriela Bungau, Adrian Bumbu
Summary: Herbal drugs have gained significant scientific interest, particularly in the past few decades, and research based on phytoconstituents is ongoing to explore their potential medicinal benefits. Daidzein (DAI), a natural phytoestrogen isoflavone found in leguminous plants like soybean and mung bean, has shown promising pharmacological properties for the treatment of various diseases. However, its limited aqueous solubility, low permeability, and poor bioavailability pose challenges for therapeutic applications. This review provides an overview of the physicochemical characteristics, pharmacokinetics, and pharmacological applications of DAI in oxidative stress, cancer, obesity, cardiovascular, neuroprotective, diabetes, ovariectomy, anxiety, and inflammation. Additionally, it discusses the recent advancements in nanotechnology-based formulations for DAI, including polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid carrier, and other drug delivery systems.
Article
Chemistry, Analytical
Mohit Vij, Neha Dand, Lalit Kumar, Amardeep Ankalgi, Pankaj Wadhwa, Sultan Alshehri, Faiyaz Shakeel, Mohammed M. Ghoneim, Prawez Alam, Shahid Ud Din Wani
Summary: An accurate and sensitive RP-HPLC bioanalytical approach was developed for the simultaneous estimation of cinnarizine (CIN) and domperidone (DOM) in rat plasma. The proposed method was validated according to the ICH M10 guidelines and showed good accuracy and precision. The limit of quantification was 5 ng/mL for both CIN and DOM, and the method was linear in the range of 5-200 ng/mL. The developed approach was robust, with a recovery rate greater than 95% and a relative uncertainty less than 2%.
Article
Chemistry, Analytical
Mohammed H. Alqarni, Faiyaz Shakeel, Ahmed I. Foudah, Tariq M. Aljarba, Wael A. Mahdi, Fatma M. Abdel Bar, Sultan Alshehri, Prawez Alam
Summary: This study developed and validated an eco-friendly HPTLC technique for measuring cinnarizine (CIN) in commercial formulations. The proposed approach used ethyl alcohol-water as the mobile phase and had a greenness score of 0.80. It was found to be linear, accurate, precise, robust, sensitive, specific, selective, stability-indicating, and reliable for pharmaceutical analysis of CIN in commercial dosage forms.
Article
Chemistry, Analytical
Nazrul Haq, Muzaffar Iqbal, Afzal Hussain, Faiyaz Shakeel, Ashfaq Ahmad, Ibrahim A. Alsarra, Mohamed Fahad AlAjmi, Asra Mahfooz, M. Ali Abouzadeh
Summary: The objective of this study was to investigate the potential of biodegradable agro-industrial waste materials as biosorbents in solid-phase extraction (SPE) technique for sample preparation. Waste coffee husk (CH) powder was collected, treated chemically, and used as an SPE adsorbent to extract pantoprazole from wastewater samples. The efficiency and regeneration capability of CH were comparable to a commercially available silica-based C18 SPE adsorbent. The developed biosorbent showed a recovery range of 93.0% to 102.0% with a %RSD of 3.72% to 12.7%.
Article
Chemistry, Analytical
Nazrul Haq, Faiyaz Shakeel, Mohammed M. Ghoneim, Syed Mohammed Basheeruddin Asdaq, Prawez Alam, Fahad Obaid Aloatibi, Sultan Alshehri
Summary: A rapid and sensitive HPLC method was used to quantify pterostilbene (PTT) in commercial capsule dosage form, solubility, and stability samples. The HPLC method utilized an RP C-18 column and a mobile phase of acetonitrile and water. PTT was detected at a wavelength of 254 nm. The HPLC method was found to be linear, accurate, precise, and sensitive, with a high determination coefficient. The method was successfully applied to determine PTT in commercial products, solubility, and stability samples.
Article
Biotechnology & Applied Microbiology
Sehrish Kakakhel, Abbas Ahmad, Wael A. Mahdi, Sultan Alshehri, Sara Aiman, Sara Begum, Sulaiman Shams, Mehnaz Kamal, Mohd. Imran, Faiyaz Shakeel, Asifullah Khan
Summary: This study prioritized vaccine candidate proteins of LSDV using genome-scan vaccinomics analyses and designed multi-epitope vaccine constructs. The LSDV-V2 construct was predicted to be the most promising candidate for stimulating humeral and cellular immunogenic responses. Experimental and clinical validation of these predicted vaccine models would be worthwhile.
BIOENGINEERING-BASEL
(2023)
Article
Engineering, Multidisciplinary
Saurabh Bhatia, Ahmed Al-Harrasi, Muhammad Jawad, Yasir Abbas Shah, Mohammed Said Al-Azri, Sana Ullah, Md Khalid Anwer, Mohammed F. Aldawsari, Esra Koca, Levent Yurdaer Aydemir
Summary: The addition of spearmint essential oil (SEO) to bovine and porcine gelatin films was found to affect their physicochemical properties and increase their antioxidant activity. The incorporation of SEO reduced the opacity, moisture content, water solubility, and elongation at break of the gelatin films, while increasing their thickness and water vapor permeability. SEM analysis showed changes in the film morphology after the addition of SEO. Furthermore, the antioxidant properties of the films were significantly improved with the addition of SEO. Therefore, incorporating SEO into gelatin-based edible films can effectively prepare an active food packaging material to prevent food oxidation.
Review
Biochemistry & Molecular Biology
Shahid Ud Din Wani, Mohammad Ali, Seema Mehdi, Mubashir Hussain Masoodi, Mohammed Iqbal Zargar, Faiyaz Shakeel
Summary: Natural polymers such as chitosan and alginate have the potential to be used as controlled release vehicles for medicines and biomolecules. Microcapsules, micrometer-sized particles that can store chemicals, have advantages in drug delivery systems due to their encapsulation effectiveness and wide range of applications. The use of microencapsulation technique offers sustained and controlled drug delivery, drug targeting, improved shelf life, and stabilization. Furthermore, the advancement in biomaterials allows for the development of more reliable and biocompatible pharmaceutical systems, and the designed microcapsules can protect essential components from harsh environments. Future development of advanced techniques can further enhance the formulation and applications of microcapsules in the pharmaceutical and medical industries.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Biochemistry & Molecular Biology
Vishal Mathur, Ozair Alam, Nadeem Siddiqui, Mukund Jha, Ajay Manaithiya, Sandhya Bawa, Naveen Sharma, Sultan Alshehri, Prawez Alam, Faiyaz Shakeel
Summary: This article discusses various scaffolds that can be used to develop DPP-4 inhibitors for the treatment of type 2 diabetes mellitus (T2DM). The study highlights different scaffolds with high DPP-4 inhibition activity and explains the potential enhancement by substituting certain atoms. Docking experiments were performed on existing drugs and their interaction with specific residues was studied. The article also describes the synthesis schemes for commercially available DPP-4 inhibitors. Overall, the use of halogenated scaffolds for developing DPP-4 inhibitors is an area of increasing interest.
Article
Chemistry, Multidisciplinary
Nazrul Haq, Mudassar Shahid, Ahmed L. Alaofi, Zeeshan Heera Ahmad, Yasser F. Alrayyes, Ibrahim A. Alsarra, Faiyaz Shakeel
Summary: A nanoemulsion-based polyherbal mouthwash was developed and evaluated for its antibacterial effects against oral pathogens. The results showed that the nanoemulsion-based mouthwash had significant antimicrobial properties against both Gram-positive and Gram-negative oral pathogens, even at lower concentrations. This suggests its potential as a treatment for various oral infections.
Article
Polymer Science
Md. Khalid Anwer, Mohammed F. F. Aldawsari, Muzaffar Iqbal, Bjad K. K. Almutairy, Gamal A. A. Soliman, M. Ali Aboudzadeh
Summary: A DSM-loaded nanoemulsion-based gel formulation was developed and evaluated for its wound healing and anti-inflammatory activity on rats. The optimized nanoemulsion showed small globule size, low polydispersity index, and high entrapment efficiency. The gel formulation incorporating the DSM-loaded nanoemulsion exhibited improved wound healing and anti-inflammatory activity.
Article
Chemistry, Physical
Rajalaxmi Sahoo, C. Reshma, D. S. Shankar Rao, C. V. Yelamaggad, S. Krishna Prasad
Summary: This study investigates the influence of the flexible spacer parity of a guest photoactive liquid crystalline dimer on the photonic bandgap features of the cholesteric and twist grain boundary smectic C phases of the host molecule. The results show that the parity of the photoactive dimer affects the width of the photonic bandgap and the blue-shift of the cholesteric phase. Additionally, the parity of the dimer also affects the layer spacing and two-dimensional periodicity of the liquid crystalline phases.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Sara Rozas, Alberto Gutierrez, Mert Atilhan, Alfredo Bol, Santiago Aparicio
Summary: This study presents a multiscale theoretical investigation on the use of bifunctional hydrophobic Deep Eutectic Solvent for carbon capture using tetrapropylammonium chloride, acetic acid, and ethanolamine. The characterization includes nanoscale analysis of CO2 absorption mechanisms and changes in liquid phase properties during gas capture.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Tabouli Eric Da-yang, Alhadji Malloum, Jean Jules Fifen, Mama Nsangou, Jeanet Conradie
Summary: In this study, the potential energy of different glycine tautomers and their interaction with Cu2+ cations was investigated. The results showed that the solvation medium and the presence of Cu2+ cations influenced the stability of glycine tautomers.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Xiaoliang Gou, Nan Ye, Qingqing Han, Junjie Cui, Long Yi Jin
Summary: In this study, amphiphilic rod-coil molecules with rigid DSA parts and flexible oligoether chains were designed and their assembly capacities were investigated. The morphology of the molecular aggregates was influenced by the pH of the solution and UV light, and the aggregates showed adsorption capacity for nitroaromatic compounds.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Shuang Liu, Liyan Shan, Cong Qi, Wenhui Zhang, Guannan Li, Bei Wang, Wei Wei
Summary: Optimizing the design of styrene-butadiene-styrene copolymer (SBS) is crucial for producing cost-effective SBS modifiers and improving road quality. This study examined the influence of SBS content and molecular structure on viscosity and compatibility. The results showed that the viscosity contribution of SBS is determined by its molecular structure and phase morphology.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Artem A. Petrov, Ekaterina A. Titova, Aydar A. Akhmadiyarov, Ilnaz T. Rakipov, Boris N. Solomonov
Summary: This work focuses on the thermochemistry of solvation of azeotropes. The enthalpies of dissolution of azeotropes in different mediums were determined, and the impact of the structure of the azeotropes on their properties in solution was discussed. A correlation between enthalpies of solvation and molar refraction was used to determine the vaporization enthalpies of azeotropes for the first time. The results were found to be consistent with literature data, obtained using direct and calculated methods. These findings contribute to the analysis of the structure-property relationships of azeotropes.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
L. V. Kamaeva, E. N. Tsiok, N. M. Chtchelkatchev
Summary: Understanding the correlations between liquids and solids allows us to predict the thermodynamic parameter range favorable for the formation of intriguing solid phases by studying liquids. In this study, we experimentally and theoretically investigated an Al-Cu-Co system within different composition ranges, and identified high-temperature solid phases. Our findings demonstrated the correlation between the boundaries of different solid phases and undercooling and viscosity in the concentration area.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
R. Aneesh Kumar, S. Jamelah Al-Otaibi, Y. Sheena Mary, Y. Shyma Mary, Nivedita Acharjee, Renjith Thomas, Renjith Raveendran Pillai, T. L. Leena
Summary: In this study, the interactions between doped and pristine coronenes and adenine nucleobases were investigated using Density Functional Theory. The optimal configurations, adsorption energies, charge transfer, and electrical properties of each complex were calculated. It was found that doped coronene had stronger adsorption strength and charge transfer compared to pristine coronene. The stability of the complexes was attributed to non-covalent interactions in the interactive region. The change in electrical conductivity of coronenes after adsorption suggested their sensitivity towards DNA bases. The predicted energy gap and prolonged recovery time for adenine-coronene configurations indicated the potential application of pristine/doped coronene in DNA detection.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Gang Zhou, Yongwei Liu, Biao Sun, Zengxin Liu, Cuicui Xu, Rulin Liu, Qi Zhang, Yongmei Wang
Summary: The CFD-DEM method was used to simulate the dust deposition pattern in the bronchus of anchor digging drivers, revealing the highest dust concentration in the vortex region of the working face. The study also found a positive correlation between dust particle diameter and bronchial deposition rate, and a negative correlation with alveolar deposition rate.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Yan Zhang, Yafei Luo, Lingkai Tang, Mingyan E, Jianping Hu
Summary: This study investigates the effects of different transition metal decorations on B12N12 nanocages on the adsorption properties of nitrosourea drugs using computational methods. The results reveal the presence of weak non-covalent interactions between metals and nanocages, and the interaction between drugs and nanocages plays a significant role in drug adsorption. Compared to free drugs, the adsorption of drugs on nanocages can facilitate electron transfer, reduce energy gaps and chemical hardness, indicating activity at the target site.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
C. I. Alcolado, J. Poblete, L. Garcia-Rio, E. Jimenez, F. J. Poblete
Summary: In this study, the selective oxidation of aromatic aldehydes was investigated using Ru(VI) as a catalyst and hexacyanoferrate (III) as a cooxidant in an alkaline medium. The reaction mechanism involves complex reaction orders for the oxidant and the aromatic aldehyde, while the reaction order for Ru(VI) is one. The proposed mechanism includes two catalytic cycles and the formation and decomposition of complexes. Quantitative structure-activity relationship analysis showed that deactivating groups in the para-position enhance the process.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Inez A. Barbieri, Marcos L. S. Oliveira, Franciele S. Bruckmann, Theodoro R. Salles, Leonardo Zancanaro, Luis F. O. Silva, Guilherme L. Dotto, Eder C. Lima, Mu. Naushad, Cristiano R. Bohn Rhoden
Summary: This study evaluated the adsorption of zolpidem on magnetic graphene oxide and synthesized magnetic graphene oxide adsorbents for zolpidem removal. The best magnetic nanoadsorbent was found to have a removal percentage of 87.07% at specific pH and temperature conditions. The results suggest that the removal of zolpidem is related to the surface chemistry of the adsorbent rather than the surface area of graphene oxide. The adsorbent showed excellent adsorption efficiency and magnetic behavior, making it a promising material for removing zolpidem from aqueous solutions.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Hongyan Huang, Chunquan Li, Siyuan Huang, Yuling Shang
Summary: This study examines the sensitivity of the thermal conductivity of water-based alumina nanofluids to changes in concentration, sphericity, and temperature. The results show that volume fraction and temperature have a significant impact on the thermal conductivity, while sphericity also needs to be considered. A support vector machine regression model was created to analyze the sensitivity of the thermal conductivity to different parameters. The findings indicate that temperature, sphericity, and volume fraction are the most sensitive variables.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Correction
Chemistry, Physical
V. M. Pergamenshchik, T. Bryk, A. Trokhymchuk
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Valentyn Rudenko, Anatolii Tolochko, Svitlana Bugaychuk, Dmytro Zhulai, Gertruda Klimusheva, Galina Yaremchuk, Tatyana Mirnaya, Yuriy Garbovskiy
Summary: This paper reports on the synthesis, structural characterization, spectral and nonlinear-optical properties of glass nanocomposites made of glass forming ionic liquid crystals and nanoparticles. The study reveals that by exciting the nanocomposites within their absorption band, a control over effective optical nonlinearities can be achieved, allowing the modification of the magnitude and sign of the effective nonlinear absorption coefficient. The proposed strategy using metal-alkanoates based glass-forming ionic liquid crystals and nanoparticles shows great potential for the development of nanophotonics and plasmonics technologies.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
