Characterization of the human SLC30A8 promoter and intronic enhancer

The pancreatic islet β-cell-enriched transcription factor Pdx-1 regulatesSlc30a8gene transcription through an intronic enhancer

(2010) Lynley D. Pound et al.   BIOCHEMICAL JOURNAL

Association between rs13266634 C/T polymorphisms of solute carrier family 30 member 8 (SLC30A8) and type 2 diabetes, impaired glucose tolerance, type 1 diabetes—A meta-analysis

(2010) Kuanfeng Xu et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion

(2010) N. Wijesekara et al.   DIABETOLOGIA

Meta-analysis and functional effects of the SLC30A8 rs13266634 polymorphism on isolated human pancreatic islets

(2010) Stéphane Cauchi et al.   MOLECULAR GENETICS AND METABOLISM

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

Effects of GCK, GCKR, G6PC2 and MTNR1B Variants on Glucose Metabolism and Insulin Secretion

(2010) Cheng Hu et al.   PLoS One

Deletion of the mouseSlc30a8gene encoding zinc transporter-8 results in impaired insulin secretion

(2009) Lynley D. Pound et al.   BIOCHEMICAL JOURNAL

Association of 18 Confirmed Susceptibility Loci for Type 2 Diabetes With Indices of Insulin Release, Proinsulin Conversion, and Insulin Sensitivity in 5,327 Nondiabetic Finnish Men

(2009) A. Stancakova et al.   DIABETES

Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants

(2009) T. J. Nicolson et al.   DIABETES

Zinc, a regulator of islet function and glucose homeostasis

(2009) N. Wijesekara et al.   DIABETES OBESITY & METABOLISM

Combined effects of single-nucleotide polymorphisms in GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes risk

(2009) E. Reiling et al.   DIABETOLOGIA

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Down-Regulation of ZnT8 Expression in INS-1 Rat Pancreatic Beta Cells Reduces Insulin Content and Glucose-Inducible Insulin Secretion

(2009) Yi Fu et al.   PLoS One

SLC30A3 Responds to Glucose- and Zinc Variations in ß-Cells and Is Critical for Insulin Production and In Vivo Glucose-Metabolism During ß-Cell Stress

(2009) Kamille Smidt et al.   PLoS One

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice

(2009) K. Lemaire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Common Nonsynonymous Single Nucleotide Polymorphism in the SLC30A8 Gene Determines ZnT8 Autoantibody Specificity in Type 1 Diabetes

(2008) J. M. Wenzlau et al.   DIABETES

A genetic variant of G6PC2 is associated with type 2 diabetes and fasting plasma glucose level in the Chinese population

(2008) C. Hu et al.   DIABETOLOGIA

Investigation of Transport Mechanisms and Regulation of Intracellular Zn2+in Pancreatic α-Cells

(2008) Armen V. Gyulkhandanyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Common Type 2 Diabetes Risk Gene Variants Associate with Gestational Diabetes

(2008) Jeannet Lauenborg et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands

(2008) C. Murgia et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES