The pancreatic islet β-cell-enriched transcription factor Pdx-1 regulatesSlc30a8gene transcription through an intronic enhancer

MafA and MafB Regulate Genes Critical to  -Cells in a Unique Temporal Manner

(2010) I. Artner et al.   DIABETES

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion

(2010) N. Wijesekara et al.   DIABETOLOGIA

Deletion of the mouseSlc30a8gene encoding zinc transporter-8 results in impaired insulin secretion

(2009) Lynley D. Pound et al.   BIOCHEMICAL JOURNAL

Association of 18 Confirmed Susceptibility Loci for Type 2 Diabetes With Indices of Insulin Release, Proinsulin Conversion, and Insulin Sensitivity in 5,327 Nondiabetic Finnish Men

(2009) A. Stancakova et al.   DIABETES

Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants

(2009) T. J. Nicolson et al.   DIABETES

Zinc, a regulator of islet function and glucose homeostasis

(2009) N. Wijesekara et al.   DIABETES OBESITY & METABOLISM

Stem Cells to Pancreatic β-Cells: New Sources for Diabetes Cell Therapy

(2009) Tingxia Guo et al.   ENDOCRINE REVIEWS

SLC30A3 Responds to Glucose- and Zinc Variations in ß-Cells and Is Critical for Insulin Production and In Vivo Glucose-Metabolism During ß-Cell Stress

(2009) Kamille Smidt et al.   PLoS One

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice

(2009) K. Lemaire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucose regulation of insulin gene expression in pancreatic β-cells

(2008) Sreenath S. Andrali et al.   BIOCHEMICAL JOURNAL

A Common Nonsynonymous Single Nucleotide Polymorphism in the SLC30A8 Gene Determines ZnT8 Autoantibody Specificity in Type 1 Diabetes

(2008) J. M. Wenzlau et al.   DIABETES

On the origin of the   cell

(2008) J. M. Oliver-Krasinski et al.   GENES & DEVELOPMENT

Investigation of Transport Mechanisms and Regulation of Intracellular Zn2+in Pancreatic α-Cells

(2008) Armen V. Gyulkhandanyan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Common Type 2 Diabetes Risk Gene Variants Associate with Gestational Diabetes

(2008) Jeannet Lauenborg et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

MafA is a dedicated activator of the insulin gene in vivo

(2008) Isabella Artner et al.   JOURNAL OF ENDOCRINOLOGY

Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression

(2008) Cyrus C Martin et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands

(2008) C. Murgia et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES