Anaplastic lymphoma kinase in human cancer

EML4-ALK Fusion Lung Cancer: A Rare Acquired Event

(2015) Sven Perner et al.   NEOPLASIA

Enhanced Antitumorigenic Effects in Glioblastoma on Double Targeting of Pleiotrophin and Its Receptor ALK

(2015) Marius Grzelinski et al.   NEOPLASIA

Anaplastic Lymphoma Kinase as a Therapeutic Target in Anaplastic Large Cell Lymphoma, Non-Small Cell Lung Cancer and Neuroblastoma

(2012) Mangeng Cheng et al.   Anti-Cancer Agents in Medicinal Chemistry

The emerging pathogenic and therapeutic importance of the anaplastic lymphoma kinase gene

(2010) Fergal C. Kelleher et al.   EUROPEAN JOURNAL OF CANCER

ALK-positive large B-cell lymphomas with cryptic SEC31A-ALK and NPM1-ALK fusions

(2010) K. Van Roosbroeck et al.   HAEMATOLOGICA

Gene Expression Profiling Uncovers Molecular Classifiers for the Recognition of Anaplastic Large-Cell Lymphoma Within Peripheral T-Cell Neoplasms

(2010) Roberto Piva et al.   JOURNAL OF CLINICAL ONCOLOGY

Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression

(2010) Xuchao Zhang et al.   Molecular Cancer

EML4-ALK Rearrangement in Non-Small Cell Lung Cancer and Non-Tumor Lung Tissues

(2009) Maria Paola Martelli et al.   AMERICAN JOURNAL OF PATHOLOGY

Anaplastic lymphoma kinase: signalling in development and disease

(2009) Ruth H. Palmer et al.   BIOCHEMICAL JOURNAL

TheEML4-ALKfusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-typeEGFRandKRAS

(2009) Daisy Wing-Sze Wong et al.   CANCER

Mutation-Independent Anaplastic Lymphoma Kinase Overexpression in Poor Prognosis Neuroblastoma Patients

(2009) L. Passoni et al.   CANCER RESEARCH

KIF5B-ALK, a Novel Fusion Oncokinase Identified by an Immunohistochemistry-based Diagnostic System for ALK-positive Lung Cancer

(2009) K. Takeuchi et al.   CLINICAL CANCER RESEARCH

Anaplastic lymphoma kinase: role in cancer pathogenesis and small-molecule inhibitor development for therapy

(2009) Thomas R Webb et al.   Expert Review of Anticancer Therapy

The EML4-ALK transcript but not the fusion protein can be expressed in reactive and neoplastic lymphoid tissues

(2009) G. Sozzi et al.   HAEMATOLOGICA

Cutaneous presentation of ALK-positive anaplastic large cell lymphoma following insect bites: evidence for an association in five cases

(2009) L. Lamant et al.   HAEMATOLOGICA

Anaplastic large cell lymphoma: one or more entities among T-cell lymphoma?

(2009) Alessandro Fornari et al.   HEMATOLOGICAL ONCOLOGY

Exon Array Profiling Detects EML4-ALK Fusion in Breast, Colorectal, and Non-Small Cell Lung Cancers

(2009) E. Lin et al.   MOLECULAR CANCER RESEARCH

High incidence of DNA mutations and gene amplifications of theALKgene in advanced sporadic neuroblastoma tumours

(2008) Helena Carén et al.   BIOCHEMICAL JOURNAL

ALK+ histiocytosis: a novel type of systemic histiocytic proliferative disorder of early infancy

(2008) J. K. C. Chan et al.   BLOOD

ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project

(2008) K. J. Savage et al.   BLOOD

EML4–ALK fusion transcript is not found in gastrointestinal and breast cancers

(2008) Y Fukuyoshi et al.   BRITISH JOURNAL OF CANCER

Genomic Alterations of Anaplastic Lymphoma Kinase May Sensitize Tumors to Anaplastic Lymphoma Kinase Inhibitors

(2008) U. McDermott et al.   CANCER RESEARCH

The Anaplastic Lymphoma Kinase Controls Cell Shape and Growth of Anaplastic Large Cell Lymphoma through Cdc42 Activation

(2008) Chiara Ambrogio et al.   CANCER RESEARCH

Multiplex Reverse Transcription-PCR Screening for EML4-ALK Fusion Transcripts

(2008) K. Takeuchi et al.   CLINICAL CANCER RESEARCH

EML4-ALK Fusion Gene and Efficacy of an ALK Kinase Inhibitor in Lung Cancer

(2008) J. P. Koivunen et al.   CLINICAL CANCER RESEARCH

C. elegans Anaplastic Lymphoma Kinase Ortholog SCD-2 Controls Dauer Formation by Modulating TGF-β Signaling

(2008) David J. Reiner et al.   CURRENT BIOLOGY

ALK-positive diffuse large B-cell lymphoma: report of three cases

(2008) Hyoun Wook Lee et al.   HEMATOLOGICAL ONCOLOGY

Hyperactivated STAT3 in ALK–positive diffuse large B-cell lymphoma with clathrin-ALK fusion

(2008) Shuji Momose et al.   HUMAN PATHOLOGY

EML4-ALK Fusion Is Linked to Histological Characteristics in a Subset of Lung Cancers

(2008) Kentaro Inamura et al.   Journal of Thoracic Oncology

Cytomorphology and Molecular Characterization of CLTC-ALK Rearrangement in 2 Cases of ALK-Positive Diffuse Large B-cell Lymphoma with Extensive Bone Marrow Involvement

(2008) Hee-Suk Choung et al.   Korean Journal of Laboratory Medicine

EML4-ALK fusion transcripts, but no NPM-, TPM3-, CLTC-, ATIC-, or TFG-ALK fusion transcripts, in non-small cell lung carcinomas

(2008) Kazuya Shinmura et al.   LUNG CANCER

Identification of ALK as a major familial neuroblastoma predisposition gene

(2008) Yaël P. Mossé et al.   NATURE

Activating mutations in ALK provide a therapeutic target in neuroblastoma

(2008) Rani E. George et al.   NATURE

Oncogenic mutations of ALK kinase in neuroblastoma

(2008) Yuyan Chen et al.   NATURE

Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

(2008) Isabelle Janoueix-Lerosey et al.   NATURE

ALK Expression in Rhabdomyosarcomas: Correlation with Histologic Subtype and Fusion Status

(2008) Diana A. Corao et al.   PEDIATRIC AND DEVELOPMENTAL PATHOLOGY

Neuroblastoma: Biology, Prognosis, and Treatment

(2008) Julie R. Park et al.   PEDIATRIC CLINICS OF NORTH AMERICA

A mouse model for EML4-ALK-positive lung cancer

(2008) M. Soda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammatory myofibroblastic tumours: where are we now?

(2007) B C Gleason et al.   JOURNAL OF CLINICAL PATHOLOGY

Development of anaplastic lymphoma kinase (ALK) small-molecule inhibitors for cancer therapy

(2007) Rongshi Li et al.   MEDICINAL RESEARCH REVIEWS