Ligand Binding Stepwise Disrupts Water Network in Thrombin: Enthalpic and Entropic Changes Reveal Classical Hydrophobic Effect

Published 2012 View Full Article

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Title
Ligand Binding Stepwise Disrupts Water Network in Thrombin: Enthalpic and Entropic Changes Reveal Classical Hydrophobic Effect
Authors
Keywords
-
Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 55, Issue 13, Pages 6094-6110
Publisher
American Chemical Society (ACS)
Online
2012-05-21
DOI
10.1021/jm300337q

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