Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation

Title
Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation
Authors
Keywords
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Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 55, Issue 21, Pages 9331-9345
Publisher
American Chemical Society (ACS)
Online
2012-09-18
DOI
10.1021/jm301039c

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