Optimization of Imidazo[4,5-b]pyridine-Based Kinase Inhibitors: Identification of a Dual FLT3/Aurora Kinase Inhibitor as an Orally Bioavailable Preclinical Development Candidate for the Treatment of Acute Myeloid Leukemia

Title
Optimization of Imidazo[4,5-b]pyridine-Based Kinase Inhibitors: Identification of a Dual FLT3/Aurora Kinase Inhibitor as an Orally Bioavailable Preclinical Development Candidate for the Treatment of Acute Myeloid Leukemia
Authors
Keywords
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Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 55, Issue 20, Pages 8721-8734
Publisher
American Chemical Society (ACS)
Online
2012-10-08
DOI
10.1021/jm300952s

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