Discovery of Two Clinical Histamine H3Receptor Antagonists:trans-N-Ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidinylmethyl)phenyl]cyclobutanecarboxamide (PF-03654746) andtrans-3-Fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]-N-(2-methylpropyl)cyclobutanecarboxamide (PF-03654764)

Title
Discovery of Two Clinical Histamine H3Receptor Antagonists:trans-N-Ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidinylmethyl)phenyl]cyclobutanecarboxamide (PF-03654746) andtrans-3-Fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]-N-(2-methylpropyl)cyclobutanecarboxamide (PF-03654764)
Authors
Keywords
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Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 54, Issue 21, Pages 7602-7620
Publisher
American Chemical Society (ACS)
Online
2011-10-08
DOI
10.1021/jm200939b

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