From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)

Title
From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)
Authors
Keywords
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Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 54, Issue 16, Pages 5836-5857
Publisher
American Chemical Society (ACS)
Online
2011-06-28
DOI
10.1021/jm200544q

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