Synthesis of Celecoxib Analogues Possessing aN-Difluoromethyl-1,2-dihydropyrid-2-one 5-Lipoxygenase Pharmacophore: Biological Evaluation as Dual Inhibitors of Cyclooxygenases and 5-Lipoxygenase with Anti-Inflammatory Activity

Published 2009 View Full Article

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Title
Synthesis of Celecoxib Analogues Possessing aN-Difluoromethyl-1,2-dihydropyrid-2-one 5-Lipoxygenase Pharmacophore: Biological Evaluation as Dual Inhibitors of Cyclooxygenases and 5-Lipoxygenase with Anti-Inflammatory Activity
Authors
Keywords
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Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 52, Issue 6, Pages 1525-1529
Publisher
American Chemical Society (ACS)
Online
2009-02-18
DOI
10.1021/jm8015188

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