Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 52, Issue 24, Pages 7938-7941Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jm901383u
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The Synthesis and characterization of a novel polycyclic azaindole based derivative is disclosed, and its binding to JAK2 is described. The compound is further evaluated for its ability to block the EPO/JAK2 signaling cascade in vitro and in vivo.
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