The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme

Comparative Molecular Dynamics Study of Human Islet Amyloid Polypeptide (IAPP) and Rat IAPP Oligomers

(2013) Guizhao Liang et al.   BIOCHEMISTRY

Effect of Proline Mutations on the Monomer Conformations of Amylin

(2013) Chi-cheng Chiu et al.   BIOPHYSICAL JOURNAL

The clearance of misfolded proteins in neurodegenerative diseases by zinc metalloproteases: An inorganic perspective

(2013) Gaetano Malgieri et al.   COORDINATION CHEMISTRY REVIEWS

Formation of insulin fragments by insulin-degrading enzyme: the role of zinc(II) and cystine bridges

(2013) Francesco Bellia et al.   JOURNAL OF MASS SPECTROMETRY

Copper(ii)–human amylin complex protects pancreatic cells from amylin toxicity

(2013) Elizabeth C. Lee et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Laser-Induced Liquid Bead Ion Desorption Mass Spectrometry: An Approach to Precisely Monitor the Oligomerization of the β-Amyloid Peptide

(2012) Mihaela Cernescu et al.   ANALYTICAL CHEMISTRY

Silibinin inhibits the toxic aggregation of human islet amyloid polypeptide

(2012) Biao Cheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibitory Mechanism of Pancreatic Amyloid Fibril Formation: Formation of the Complex between Tea Catechins and the Fragment of Residues 22–27

(2012) Miya Kamihira-Ishijima et al.   BIOCHEMISTRY

Analysis of the Inhibition and Remodeling of Islet Amyloid Polypeptide Amyloid Fibers by Flavanols

(2012) Ping Cao et al.   BIOCHEMISTRY

Role of Aromatic Interactions in Amyloid Formation by Islet Amyloid Polypeptide

(2012) Ling-Hsien Tu et al.   BIOCHEMISTRY

Aggregation of islet amyloid polypeptide: from physical chemistry to cell biology

(2012) Ping Cao et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Degradation of islet amyloid polypeptide by neprilysin

(2012) H. Guan et al.   DIABETOLOGIA

Investigation of the Copper Binding Site on the Human Islet Amyloid Polypeptide Hormone

(2012) Mi-Ji Kim et al.   EUROPEAN JOURNAL OF MASS SPECTROMETRY

Matrix Metalloproteinase-9 Reduces Islet Amyloid Formation by Degrading Islet Amyloid Polypeptide

(2012) Kathryn Aston-Mourney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metal ions affect insulin-degrading enzyme activity

(2012) Giuseppe Grasso et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Metallostasis and amyloid β-degrading enzymes

(2012) Giuseppe Grasso et al.   Metallomics

Copper(I) and Copper(II) Inhibit Aβ Peptides Proteolysis by Insulin-Degrading Enzyme Differently: Implications for Metallostasis Alteration in Alzheimer’s Disease

(2011) Giuseppe Grasso et al.   CHEMISTRY-A EUROPEAN JOURNAL

Copper(ii) complexes of rat amylin fragments

(2011) Csilla Kállay et al.   DALTON TRANSACTIONS

Coffee Components Inhibit Amyloid Formation of Human Islet Amyloid Polypeptide in Vitro: Possible Link between Coffee Consumption and Diabetes Mellitus

(2011) Biao Cheng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Mechanism of Amylin Fibrillization Enhancement by Heparin

(2011) Suman Jha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ion Mobility Separation Coupled with MS Detects Two Structural States of Alzheimer's Disease Aβ1–40 Peptide Oligomers

(2011) Marcin Kłoniecki et al.   JOURNAL OF MOLECULAR BIOLOGY

A Two-Site Mechanism for the Inhibition of IAPP Amyloidogenesis by Zinc

(2011) Samer Salamekh et al.   JOURNAL OF MOLECULAR BIOLOGY

The Amyloid Formation Mechanism in Human IAPP: Dimers Have β-Strand Monomer−Monomer Interfaces

(2011) Nicholas F. Dupuis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Islet Amyloid Polypeptide, Islet Amyloid, and Diabetes Mellitus

(2011) Per Westermark et al.   PHYSIOLOGICAL REVIEWS

The chaperone proteins HSP70, HSP40/DnaJ and GRP78/BiP suppress misfolding and formation of β-sheet-containing aggregates by human amylin: a potential role for defective chaperone biology in Type 2 diabetes

(2010) Vita Chien et al.   BIOCHEMICAL JOURNAL

Copper-induced cytotoxicity: reactive oxygen species or islet amyloid polypeptide oligomer formation

(2010) Ye-Ping Yu et al.   CHEMICAL COMMUNICATIONS

Neprilysin Impedes Islet Amyloid Formation by Inhibition of Fibril Formation Rather Than Peptide Degradation

(2010) Sakeneh Zraika et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human pro-islet amyloid polypeptide (ProIAPP1–48) forms amyloid fibrils and amyloid spherulites in vitro

(2010) Christopher Exley et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Ubiquitin Is a Novel Substrate for Human Insulin-Degrading Enzyme

(2010) Luis A. Ralat et al.   JOURNAL OF MOLECULAR BIOLOGY

Role of Zinc in Human Islet Amyloid Polypeptide Aggregation

(2010) Jeffrey R. Brender et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The use of mass spectrometry to study amyloid-β peptides

(2010) Giuseppe Grasso   MASS SPECTROMETRY REVIEWS

The proteolytic activity of insulin-degrading enzyme: a mass spectrometry study

(2009) Giuseppe Grasso et al.   JOURNAL OF MASS SPECTROMETRY

Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-α, and Amylin by Human Insulin-Degrading Enzyme

(2009) Qing Guo et al.   JOURNAL OF MOLECULAR BIOLOGY

Zinc and diabetes — clinical links and molecular mechanisms

(2009) Judith Jansen et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Altered metabolism of copper, zinc, and magnesium is associated with increased levels of glycated hemoglobin in patients with diabetes mellitus

(2009) Alena Viktorínová et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice

(2009) K. Lemaire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How the binding and degrading capabilities of insulin degrading enzyme are affected by ubiquitin

(2008) Giuseppe Grasso et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Somatostatin: A Novel Substrate and a Modulator of Insulin-Degrading Enzyme Activity

(2008) Chiara Ciaccio et al.   JOURNAL OF MOLECULAR BIOLOGY

Copper(II) inhibits the formation of amylin amyloid in vitro

(2007) Benjamin Ward et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Amyloid accomplices and enforcers

(2004) Andrei T. Alexandrescu   PROTEIN SCIENCE