Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake

MicroRNAs in Metabolic Disease

(2013) Carlos Fernández-Hernando et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Association of germline microRNA SNPs in pre-miRNA flanking region and breast cancer risk and survival: the Carolina Breast Cancer Study

(2013) Jeannette T. Bensen et al.   CANCER CAUSES & CONTROL

MicroRNA-185 suppresses proliferation, invasion, migration, and tumorigenicity of human prostate cancer cells through targeting androgen receptor

(2013) Fajun Qu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

MicroRNAs 185, 96, and 223 Repress Selective High-Density Lipoprotein Cholesterol Uptake through Posttranscriptional Inhibition

(2013) L. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

MiR-152 and miR-185 co-contribute to ovarian cancer cells cisplatin sensitivity by targeting DNMT1 directly: a novel epigenetic therapy independent of decitabine

(2013) Y Xiang et al.   ONCOGENE

SREBP: a novel therapeutic target

(2012) X. Xiao et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals

(2012) Young-Ah Moon et al.   Cell Metabolism

Expanding Roles for SREBP in Metabolism

(2012) Wei Shao et al.   Cell Metabolism

MicroRNAs 125a and 455 Repress Lipoprotein-Supported Steroidogenesis by Targeting Scavenger Receptor Class B Type I in Steroidogenic Cells

(2012) Z. Hu et al.   MOLECULAR AND CELLULAR BIOLOGY

Deciphering the transcriptional regulation of microRNA genes in humans with ACTLocater

(2012) Zhen-Dong Xiao et al.   NUCLEIC ACIDS RESEARCH

Preventing Phosphorylation of Sterol Regulatory Element-Binding Protein 1a by MAP-Kinases Protects Mice from Fatty Liver and Visceral Obesity

(2012) Jorg Kotzka et al.   PLoS One

Discovering Dysfunction of Multiple MicroRNAs Cooperation in Disease by a Conserved MicroRNA Co-Expression Network

(2012) Yun Xiao et al.   PLoS One

The Role of MicroRNAs in Cholesterol Efflux and Hepatic Lipid Metabolism

(2011) Kathryn J. Moore et al.   Annual Review of Nutrition

MicroRNA Modulation of Cholesterol Homeostasis

(2011) Carlos Fernández-Hernando et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mechanisms regulating hepatic SR-BI expression and their impact on HDL metabolism

(2011) Andrea Leiva et al.   ATHEROSCLEROSIS

Hypocholesterolemia, foam cell accumulation, but no atherosclerosis in mice lacking ABC-transporter A1 and scavenger receptor BI

(2011) Ying Zhao et al.   ATHEROSCLEROSIS

Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques

(2011) Jing-Jie Tang et al.   Cell Metabolism

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma

(2011) Zuping Zhang et al.   Molecular Cancer

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

SREBPs: metabolic integrators in physiology and metabolism

(2011) Tae-Il Jeon et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes

(2010) Jorg Kotzka et al.   ATHEROSCLEROSIS

miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells

(2010) Ming Liu et al.   CANCER LETTERS

Insulin signaling in fatty acid and fat synthesis: a transcriptional perspective

(2010) Roger HF Wong et al.   CURRENT OPINION IN PHARMACOLOGY

Accessibility of Cholesterol in Endoplasmic Reticulum Membranes and Activation of SREBP-2 Switch Abruptly at a Common Cholesterol Threshold

(2010) Anna Sokolov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-185 suppresses tumor growth and progression by targeting the Six1 oncogene in human cancers

(2010) J S Imam et al.   ONCOGENE

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

(2010) S. H. Najafi-Shoushtari et al.   SCIENCE

microRNAs and cholesterol metabolism

(2010) Kathryn J. Moore et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A Phosphorylation Cascade Controls the Degradation of Active SREBP1

(2009) Maria T. Bengoechea-Alonso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Salt-inducible Kinase Regulates Hepatic Lipogenesis by Controlling SREBP-1c Phosphorylation

(2009) Young-Sil Yoon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells

(2008) Alexander Marson et al.   CELL

Switch-like Control of SREBP-2 Transport Triggered by Small Changes in ER Cholesterol: A Delicate Balance

(2008) Arun Radhakrishnan et al.   Cell Metabolism

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS