Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion

High-Fat Diet Triggers Inflammation-Induced Cleavage of SIRT1 in Adipose Tissue To Promote Metabolic Dysfunction

(2012) Angeliki Chalkiadaki et al.   Cell Metabolism

Gut-liver interaction in triglyceride-rich lipoprotein metabolism

(2011) Changting Xiao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Nutrient-induced inflammation in the intestine

(2011) Yong Ji et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Lack of Interleukin-1 Receptor I (IL-1RI) Protects Mice From High-Fat Diet-Induced Adipose Tissue Inflammation Coincident With Improved Glucose Homeostasis

(2011) F. C. McGillicuddy et al.   DIABETES

Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells

(2011) Timea Csak et al.   HEPATOLOGY

More than Inflammation: Interleukin-1β Polymorphisms and the Lipid Metabolism

(2011) Mihai G. Netea et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Interleukin 1B Variant -1473G/C (rs1143623) Influences Triglyceride and Interleukin 6 Metabolism

(2011) Javier Delgado-Lista et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Inflammasome is a central player in the induction of obesity and insulin resistance

(2011) R. Stienstra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nlrp3 inflammasome: contributions to intestinal homeostasis

(2011) Md. Hasan Zaki et al.   TRENDS IN IMMUNOLOGY

The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity

(2010) Rinke Stienstra et al.   Cell Metabolism

A novel multiprotein complex is required to generate the prechylomicron transport vesicle from intestinal ER

(2010) Shahzad Siddiqi et al.   JOURNAL OF LIPID RESEARCH

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Genetic variation within IL18 is associated with insulin levels, insulin resistance and postprandial measures

(2010) M.C. Smart et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Caspase-1 recognizes extended cleavage sites in its natural substrates

(2009) Jerry Shen et al.   ATHEROSCLEROSIS

Immune Responses to the Microbiota at the Intestinal Mucosal Surface

(2009) Breck A. Duerkop et al.   IMMUNITY

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Kupffer cell products and interleukin 1? directly promote VLDL secretion and apoB mRNA up-regulation in rodent hepatocytes

(2008) Nerea Bartolomé et al.   Innate Immunity

Targeted Peptidecentric Proteomics Reveals Caspase-7 as a Substrate of the Caspase-1 Inflammasomes

(2008) Mohamed Lamkanfi et al.   MOLECULAR & CELLULAR PROTEOMICS

Caspase-mediated Degradation of PPARγ Proteins in Adipocytes

(2008) Fang He et al.   Obesity