Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells

The mammalian ABC transporter ABCA1 induces lipid-dependent drug sensitivity in yeast

(2011) Tomasz Bocer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

(2011) Kezhong Zhang et al.   EMBO JOURNAL

Hepatic Nuclear Factor 1α (HNF1α) Dysfunction Down-regulates X-box-binding Protein 1 (XBP1) and Sensitizes β-Cells to Endoplasmic Reticulum Stress

(2011) Clare L. Kirkpatrick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sorting of GPI-anchored proteins into ER exit sites by p24 proteins is dependent on remodeled GPI

(2011) Morihisa Fujita et al.   JOURNAL OF CELL BIOLOGY

The yeast p24 complex regulates GPI-anchored protein transport and quality control by monitoring anchor remodeling

(2011) Guillaume A. Castillon et al.   MOLECULAR BIOLOGY OF THE CELL

ER Stress and Its Functional Link to Mitochondria: Role in Cell Survival and Death

(2011) J. D. Malhotra et al.   Cold Spring Harbor Perspectives in Biology

Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy

(2010) S Lépine et al.   CELL DEATH AND DIFFERENTIATION

p24 family type 1 transmembrane proteins are required for insulin biosynthesis and secretion in pancreatic β-cells

(2010) Liling Zhang et al.   FEBS LETTERS

Orm family proteins mediate sphingolipid homeostasis

(2010) David K. Breslow et al.   NATURE

Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control

(2010) S. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response

(2009) Stefka D. Spassieva et al.   BIOCHEMICAL JOURNAL

Divergent Effects of PERK and IRE1 Signaling on Cell Viability

(2009) Jonathan H. Lin et al.   PLoS One

Protection of C. elegans from Anoxia by HYL-2 Ceramide Synthase

(2009) V. Menuz et al.   SCIENCE

Comprehensive Characterization of Genes Required for Protein Folding in the Endoplasmic Reticulum

(2009) M. C. Jonikas et al.   SCIENCE

Mammalian GPI-anchored proteins require p24 proteins for their efficient transport from the ER to the plasma membrane

(2008) Satoshi Takida et al.   BIOCHEMICAL JOURNAL

The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus

(2008) Décio L. Eizirik et al.   ENDOCRINE REVIEWS

GRP78, but Not Protein-disulfide Isomerase, Partially Reverses Hyperglycemia-induced Inhibition of Insulin Synthesis and Secretion in Pancreatic β-Cells

(2008) Liling Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thematic Review Series: Sphingolipids.New insights into sphingolipid metabolism and function in budding yeast

(2008) Robert C. Dickson   JOURNAL OF LIPID RESEARCH

Involvement of chronic stresses in rat islet and INS-1 cell glucotoxicity induced by intermittent high glucose

(2008) Zhi-Qiang Hou et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Trans-Golgi Network and Endosome Dynamics Connect Ceramide Homeostasis with Regulation of the Unfolded Protein Response and TOR Signaling in Yeast

(2008) Carl J. Mousley et al.   MOLECULAR BIOLOGY OF THE CELL